Akroma's Will

Choose one. If you control a commander as you cast this spell, you may choose both instead.
• Creatures you control gain flying, vigilance, and double strike until end of turn.
• Creatures you control gain lifelink, indestructible, and protection from each color until end of turn.

Boromir, Warden of the Tower

Vigilance
Whenever an opponent casts a spell, if no mana was spent to cast it, counter that spell.
Sacrifice Boromir: Creatures you control gain indestructible until end of turn. The Ring tempts you.

Gideon, Battle-Forged

+2: Up to one target creature an opponent controls attacks Gideon during its controller's next turn if able.
+1: Until your next turn, target creature gains indestructible. Untap that creature.
0: Until end of turn, Gideon becomes a 4/4 Human Soldier creature with indestructible that's still a planeswalker. Prevent all damage that would be dealt to him this turn.

Kytheon, Hero of Akros

At end of combat, if Kytheon and at least two other creatures attacked this combat, exile Kytheon, then return him to the battlefield transformed under his owner's control.
{2}{W}: Kytheon gains indestructible until end of turn.

Kytheon, Hero of Akros // Gideon, Battle-Forged

Final Showdown

Spree (Choose one or more additional costs.)
+ {1} — All creatures lose all abilities until end of turn.
+ {1} — Choose a creature you control. It gains indestructible until end of turn.
+ {3}{W}{W} — Destroy all creatures.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Day of Judgment

Farewell

Choose one or more —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all graveyards.

Unbreakable Formation

Creatures you control gain indestructible until end of turn.
Addendum — If you cast this spell during your main phase, put a +1/+1 counter on each of those creatures and they gain vigilance until end of turn.

Your Temple Is Under Attack

Choose one —
• Pray for Protection — Creatures you control gain indestructible until end of turn.
• Strike a Deal — You and target opponent each draw two cards.

Make a Stand

Creatures you control get +1/+0 and gain indestructible until end of turn. (Damage and effects that say "destroy" don't destroy them.)

Avacyn, Angel of Hope

Flying, vigilance, indestructible
Other permanents you control have indestructible.

Selfless Savior

Sacrifice this creature: Another target creature you control gains indestructible until end of turn. (Damage and effects that say "destroy" don't destroy it.)

Darksteel Mutation

Enchant creature
Enchanted creature is an Insect artifact creature with base power and toughness 0/1 and has indestructible, and it loses all other abilities, card types, and creature types.

The Walls of Ba Sing Se

Defender
Other permanents you control have indestructible.

Dawn's Truce

Gift a card (You may promise an opponent a gift as you cast this spell. If you do, they draw a card before its other effects.)
You and permanents you control gain hexproof until end of turn. If the gift was promised, permanents you control also gain indestructible until end of turn.

Restoration Magic

Tiered (Choose one additional cost.)
• Cure — {0} — Target permanent gains hexproof and indestructible until end of turn.
• Cura — {1} — Target permanent gains hexproof and indestructible until end of turn. You gain 3 life.
• Curaga — {3}{W} — Permanents you control gain hexproof and indestructible until end of turn. You gain 6 life.

Armageddon

Myojin of Cleansing Fire

Myojin of Cleansing Fire enters with a divinity counter on it if you cast it from your hand.
Myojin of Cleansing Fire has indestructible as long as it has a divinity counter on it.
Remove a divinity counter from Myojin of Cleansing Fire: Destroy all other creatures.

Flare of Fortitude

You may sacrifice a nontoken white creature rather than pay this spell's mana cost.
Until end of turn, your life total can't change, and permanents you control gain hexproof and indestructible.

Mondrak, Glory Dominus

If one or more tokens would be created under your control, twice that many of those tokens are created instead.
{1}{W/P}{W/P}, Sacrifice two other artifacts and/or creatures: Put an indestructible counter on Mondrak. ({W/P} can be paid with either {W} or 2 life.)

Mageta the Lion

{2}{W}{W}, {T}, Discard two cards: Destroy all creatures except for Mageta. Those creatures can't be regenerated.