Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Blinding Souleater

{W/P}, {T}: Tap target creature. ({W/P} can be paid with either {W} or 2 life.)

Norn's Annex

({W/P} can be paid with either {W} or 2 life.)
Creatures can't attack you or planeswalkers you control unless their controller pays {W/P} for each of those creatures.

Nykthos, Shrine to Nyx

{T}: Add {C}.
{2}, {T}: Choose a color. Add an amount of mana of that color equal to your devotion to that color. (Your devotion to a color is the number of mana symbols of that color in the mana costs of permanents you control.)

Counterspell

Godless Shrine

({T}: Add {W} or {B}.)
As this land enters, you may pay 2 life. If you don't, it enters tapped.

Mana Drain

Counter target spell. At the beginning of your next main phase, add an amount of {C} equal to that spell's mana value.

Marrow Shards

({W/P} can be paid with either {W} or 2 life.)
Marrow Shards deals 1 damage to each attacking creature.

Skrelv, Defector Mite

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
Skrelv can't block.
{W/P}, {T}: Choose a color. Another target creature you control gains toxic 1 and hexproof from that color until end of turn. It can't be blocked by creatures of that color this turn. ({W/P} can be paid with either {W} or 2 life.)

Sorin, Ravenous Neonate

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
+2: Create a Food token.
−1: Sorin deals damage equal to the amount of life you gained this turn to any target.
−6: Gain control of target creature. It becomes a Vampire in addition to its other types. Put a lifelink counter on it if you control a white permanent other than that creature or Sorin.

Sorin of House Markov

Lifelink
Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
At the beginning of each of your postcombat main phases, if you gained 3 or more life this turn, exile Sorin, then return him to the battlefield transformed under his owner's control.

Sorin of House Markov // Sorin, Ravenous Neonate

Karlov of the Ghost Council

Whenever you gain life, put two +1/+1 counters on Karlov.
{W}{B}, Remove six +1/+1 counters from Karlov: Exile target creature.

Blood Artist

Whenever this creature or another creature dies, target player loses 1 life and you gain 1 life.

Soul's Attendant

Whenever another creature enters, you may gain 1 life.

Epicure of Blood

Whenever you gain life, each opponent loses 1 life.

Island

Cathedral Membrane

({W/P} can be paid with either {W} or 2 life.)
Defender
When this creature dies during combat, it deals 6 damage to each creature it blocked this combat.

Bloodthirsty Conqueror

Flying, deathtouch
Whenever an opponent loses life, you gain that much life. (Damage causes loss of life.)

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Shipwreck Marsh

This land enters tapped unless you control two or more other lands.
{T}: Add {U} or {B}.

Caves of Koilos

{T}: Add {C}.
{T}: Add {W} or {B}. This land deals 1 damage to you.

Hex Parasite

{X}{B/P}: Remove up to X counters from target permanent. For each counter removed this way, this creature gets +1/+0 until end of turn. ({B/P} can be paid with either {B} or 2 life.)

Indulging Patrician

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your end step, if you gained 3 or more life this turn, each opponent loses 3 life.

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Tezzeret's Gambit

({U/P} can be paid with either {U} or 2 life.)
Draw two cards, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

False Cure

Until end of turn, whenever a player gains life, that player loses 2 life for each 1 life they gained.

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, this creature gets +5/+5 and has flying.

Flooded Strand

{T}, Pay 1 life, Sacrifice this land: Search your library for a Plains or Island card, put it onto the battlefield, then shuffle.

Thalia, Guardian of Thraben

First strike
Noncreature spells cost {1} more to cast.

Tainted Remedy

If an opponent would gain life, that player loses that much life instead.

Underground River

{T}: Add {C}.
{T}: Add {U} or {B}. This land deals 1 damage to you.

Raffine's Tower

({T}: Add {W}, {U}, or {B}.)
This land enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Hallowed Fountain

({T}: Add {W} or {U}.)
As this land enters, you may pay 2 life. If you don't, it enters tapped.

Negate

Gitaxian Probe

({U/P} can be paid with either {U} or 2 life.)
Look at target player's hand.
Draw a card.

Sensei's Divining Top

{1}: Look at the top three cards of your library, then put them back in any order.
{T}: Draw a card, then put this artifact on top of its owner's library.

Dispatch

Tap target creature.
Metalcraft — If you control three or more artifacts, exile that creature.

Vault Skirge

({B/P} can be paid with either {B} or 2 life.)
Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)

Azorius Signet

Porcelain Legionnaire

({W/P} can be paid with either {W} or 2 life.)
First strike

Dovin's Veto

This spell can't be countered.
Counter target noncreature spell.

Shattered Sanctum

This land enters tapped unless you control two or more other lands.
{T}: Add {W} or {B}.

Aura of Silence

Artifact and enchantment spells your opponents cast cost {2} more to cast.
Sacrifice this enchantment: Destroy target artifact or enchantment.

Drana and Linvala

Flying, vigilance
Activated abilities of creatures your opponents control can't be activated.
Drana and Linvala has all activated abilities of all creatures your opponents control. You may spend mana as though it were mana of any color to activate those abilities.

Sol Ring

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with this creature's toughness.

Swamp

Grand Arbiter Augustin IV

White spells you cast cost {1} less to cast.
Blue spells you cast cost {1} less to cast.
Spells your opponents cast cost {1} more to cast.

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Thalia, Heretic Cathar

First strike
Creatures and nonbasic lands your opponents control enter tapped.

Oloro, Ageless Ascetic

At the beginning of your upkeep, you gain 2 life.
Whenever you gain life, you may pay {1}. If you do, draw a card and each opponent loses 1 life.
At the beginning of your upkeep, if Oloro is in the command zone, you gain 2 life.

Orzhov Signet

Seachrome Coast

This land enters tapped unless you control two or fewer other lands.
{T}: Add {W} or {U}.

Grand Abolisher

During your turn, your opponents can't cast spells or activate abilities of artifacts, creatures, or enchantments.

Mana Leak

Counter target spell unless its controller pays {3}.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Watery Grave

({T}: Add {U} or {B}.)
As this land enters, you may pay 2 life. If you don't, it enters tapped.

Deserted Beach

This land enters tapped unless you control two or more other lands.
{T}: Add {W} or {U}.

Dimir Signet

Spellskite

{U/P}: Change a target of target spell or ability to this creature. ({U/P} can be paid with either {U} or 2 life.)

Ancient Tomb

{T}: Add {C}{C}. This land deals 2 damage to you.

Dismember

({B/P} can be paid with either {B} or 2 life.)
Target creature gets -5/-5 until end of turn.

Creeping Bloodsucker

At the beginning of your upkeep, this creature deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Condemn

Put target attacking creature on the bottom of its owner's library. Its controller gains life equal to its toughness.

Soul Warden

Whenever another creature enters, you gain 1 life.

Adarkar Wastes

{T}: Add {C}.
{T}: Add {W} or {U}. This land deals 1 damage to you.

Marsh Flats

{T}, Pay 1 life, Sacrifice this land: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Spined Thopter

({U/P} can be paid with either {U} or 2 life.)
Flying

Polluted Bonds

Whenever a land an opponent controls enters, that player loses 2 life and you gain 2 life.

Rona, Tolarian Obliterator

Trample
Whenever a source deals damage to Rona, that source's controller exiles a card from their hand at random. If it's a land card, you may put it onto the battlefield under your control. Otherwise, you may cast it without paying its mana cost.

Rona, Herald of Invasion

Whenever you cast a legendary spell, untap Rona.
{T}: Draw a card, then discard a card.
{5}{B/P}: Transform Rona. Activate only as a sorcery. ({B/P} can be paid with either {B} or 2 life.)

Rona, Herald of Invasion // Rona, Tolarian Obliterator

The Meathook Massacre

When The Meathook Massacre enters, each creature gets -X/-X until end of turn.
Whenever a creature you control dies, each opponent loses 1 life.
Whenever a creature an opponent controls dies, you gain 1 life.

Plains

Polluted Delta

{T}, Pay 1 life, Sacrifice this land: Search your library for an Island or Swamp card, put it onto the battlefield, then shuffle.

Gitaxian Mindstinger

Deathtouch
Whenever this creature deals combat damage to a player or battle, draw a card.

Aetherblade Agent

Deathtouch
{4}{U/P}: Transform this creature. Activate only as a sorcery. ({U/P} can be paid with either {U} or 2 life.)

Aetherblade Agent // Gitaxian Mindstinger

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Swan Song

Counter target enchantment, instant, or sorcery spell. Its controller creates a 2/2 blue Bird creature token with flying.

Marauding Blight-Priest

Phyrexian Metamorph

({U/P} can be paid with either {U} or 2 life.)
You may have this creature enter as a copy of any artifact or creature on the battlefield, except it's an artifact in addition to its other types.

Mental Misstep

({U/P} can be paid with either {U} or 2 life.)
Counter target spell with mana value 1.

Concealed Courtyard

This land enters tapped unless you control two or fewer other lands.
{T}: Add {W} or {B}.

Lavinia, Azorius Renegade

Each opponent can't cast noncreature spells with mana value greater than the number of lands that player controls.
Whenever an opponent casts a spell, if no mana was spent to cast it, counter that spell.

Apostle's Blessing

({W/P} can be paid with either {W} or 2 life.)
Target artifact or creature you control gains protection from artifacts or from the color of your choice until end of turn.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Darkslick Shores

This land enters tapped unless you control two or fewer other lands.
{T}: Add {U} or {B}.