Aunt May

Whenever another creature you control enters, you gain 1 life. If it's a Spider, put a +1/+1 counter on it.

Silk, Web Weaver

Web-slinging {1}{G}{W} (You may cast this spell for {1}{G}{W} if you also return a tapped creature you control to its owner's hand.)
Whenever you cast a creature spell, create a 1/1 green and white Human Citizen creature token.
{3}{G}{W}: Creatures you control get +2/+2 and gain vigilance until end of turn.

Spider-Man, Web-Slinger

Web-slinging {W} (You may cast this spell for {W} if you also return a tapped creature you control to its owner's hand.)

Mary Jane Watson

Whenever a Spider you control enters, draw a card. This ability triggers only once each turn.

Spider-Girl, Legacy Hero

During your turn, Spider-Girl has flying.
When Spider-Girl leaves the battlefield, create a 1/1 green and white Human Citizen creature token.