Unstable Experiment

Target player draws a card, then up to one target creature you control connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on that creature.)

Getting

Doctor Octopus, Master Planner

Other Villains you control get +2/+2.
Your maximum hand size is eight.
At the beginning of your end step, if you have fewer than eight cards in hand, draw cards equal to the difference.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Ominous Asylum

This land enters tapped.
{T}: Add {B} or {R}.
{4}, {T}: Surveil 1. (Look at the top card of your library. You may put it into your graveyard.)

Inner Demons Gangsters

Discard a card: This creature gets +1/+0 and gains menace until end of turn. Activate only as a sorcery. (It can't be blocked except by two or more creatures.)

Molten Man, Inferno Incarnate

When Molten Man enters, search your library for a basic Mountain card, put it onto the battlefield tapped, then shuffle.
Molten Man gets +1/+1 for each Mountain you control.
When Molten Man leaves the battlefield, sacrifice a land.

Venom, Evil Unleashed

Deathtouch
{2}{B}, Exile this card from your graveyard: Put two +1/+1 counters on target creature. It gains deathtouch until end of turn. Activate only as a sorcery.

Rotting Regisaur

At the beginning of your upkeep, discard a card.

The Death of Gwen Stacy

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Destroy target creature.
II — Each player may discard a card. Each player who doesn't loses 3 life.
III — Exile any number of target players' graveyards.

Mountain

Scorpion's Sting

Target creature gets -3/-3 until end of turn.

Common Crook

When this creature dies, create a Treasure token. (It's an artifact with "{T}, Sacrifice this token: Add one mana of any color.")

Green Goblin

Flying, menace
Spells you cast from your graveyard cost {2} less to cast.
Goblin Formula — Each nonland card in your graveyard has mayhem. The mayhem cost is equal to its mana cost. (You may cast a card from your graveyard for its mayhem cost if you discarded it this turn. Timing rules still apply.)

Norman Osborn

Norman Osborn can't be blocked.
Whenever Norman Osborn deals combat damage to a player, he connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on this creature.)
{1}{U}{B}{R}: Transform Norman Osborn. Activate only as a sorcery.

Norman Osborn // Green Goblin

Mechanical Mobster

When this creature enters, exile up to one target card from a graveyard. Target creature you control connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on that creature.)

Negate

Swamp

Bloodfell Caves

This land enters tapped.
When this land enters, you gain 1 life.
{T}: Add {B} or {R}.

Highland Lake

This land enters tapped.
{T}: Add {U} or {R}.

Faithless Looting

Draw two cards, then discard two cards.
Flashback {2}{R} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Spider-Sense

Web-slinging {U} (You may cast this spell for {U} if you also return a tapped creature you control to its owner's hand.)
Counter target instant spell, sorcery spell, or triggered ability.

Secret Identity

Choose one —
• Conceal — Until end of turn, target creature you control becomes a Citizen with base power and toughness 1/1 and gains hexproof.
• Reveal — Until end of turn, target creature you control becomes a Hero with base power and toughness 3/4 and gains flying and vigilance.

Tormenting Voice

As an additional cost to cast this spell, discard a card.
Draw two cards.

Dismal Backwater

This land enters tapped.
When this land enters, you gain 1 life.
{T}: Add {U} or {B}.

Hydro-Man, Fluid Felon

Whenever you cast a blue spell, if Hydro-Man is a creature, he gets +1/+1 until end of turn.
At the beginning of your end step, untap Hydro-Man. Until your next turn, he becomes a land and gains "{T}: Add {U}." (He's not a creature during that time.)

Electro's Bolt

Electro's Bolt deals 4 damage to target creature.
Mayhem {1}{R} (You may cast this card from your graveyard for {1}{R} if you discarded it this turn. Timing rules still apply.)

Hobgoblin, Mantled Marauder

Flying, haste
Whenever you discard a card, Hobgoblin gets +2/+0 until end of turn.

Prowler, Clawed Thief

Menace (This creature can't be blocked except by two or more creatures.)
Whenever another Villain you control enters, Prowler connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on this creature.)

Vulture, Scheming Scavenger

Flying
Whenever Vulture attacks, other Villains you control gain flying until end of turn.

Shadow of the Goblin

Unreliable Visions — At the beginning of your first main phase, discard a card. If you do, draw a card.
Undying Vengeance — Whenever you play a land or cast a spell from anywhere other than your hand, this enchantment deals 1 damage to each opponent.

Amazing Acrobatics

Choose one or both —
• Counter target spell.
• Tap one or two target creatures.

Mysterio, Master of Illusion

When Mysterio enters, create a 3/3 blue Illusion Villain creature token for each nontoken Villain you control. Exile those tokens when Mysterio leaves the battlefield.

Oscorp Industries

This land enters tapped.
When this land enters from a graveyard, you lose 2 life.
{T}: Add {U}, {B}, or {R}.
Mayhem (You may play this card from your graveyard if you discarded it this turn. Timing rules still apply.)

Pumpkin Bombardment

As an additional cost to cast this spell, discard a card or pay {2}.
Pumpkin Bombardment deals 3 damage to target creature.

Ultimate Green Goblin

At the beginning of your upkeep, discard a card, then create a Treasure token.
Mayhem {2}{B/R} (You may cast this card from your graveyard for {2}{B/R} if you discarded it this turn. Timing rules still apply.)

Armillary Sphere

{2}, {T}, Sacrifice this artifact: Search your library for up to two basic land cards, reveal them, put them into your hand, then shuffle.

Black Cat, Cunning Thief

When Black Cat enters, look at the top nine cards of target opponent's library, exile two of them face down, then put the rest on the bottom of their library in a random order. You may play the exiled cards for as long as they remain exiled. Mana of any type can be spent to cast spells this way.

Sandman's Quicksand

Mayhem {3}{B} (You may cast this card from your graveyard for {3}{B} if you discarded it this turn. Timing rules still apply.)
All creatures get -2/-2 until end of turn. If this spell's mayhem cost was paid, creatures your opponents control get -2/-2 until end of turn instead.

Scorpion, Seething Striker

Deathtouch
At the beginning of your end step, if a creature died this turn, target creature you control connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on that creature.)

Sol Ring

Mob Lookout

When this creature enters, target creature you control connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on that creature.)

Shriek, Treblemaker

At the beginning of your first main phase, you may discard a card. When you do, target creature can't block this turn.
Sonic Blast — Whenever a creature an opponent controls dies, Shriek deals 1 damage to that player.

Merciless Enforcers

Lifelink
{3}{B}: This creature deals 1 damage to each opponent.

Doc Ock's Henchmen

Flash
Whenever this creature attacks, it connives. (Draw a card, then discard a card. If you discarded a nonland card, put a +1/+1 counter on this creature.)

Carnage, Crimson Chaos

Trample
When Carnage enters, return target creature card with mana value 3 or less from your graveyard to the battlefield. It gains "This creature attacks each combat if able" and "When this creature deals combat damage to a player, sacrifice it."
Mayhem {B}{R}

Flying Octobot

Flying
Whenever another Villain you control enters, put a +1/+1 counter on this creature. This ability triggers only once each turn.

Island

Chameleon, Master of Disguise

You may have Chameleon enter as a copy of a creature you control, except his name is Chameleon, Master of Disguise.
Mayhem {2}{U} (You may cast this card from your graveyard for {2}{U} if you discarded it this turn. Timing rules still apply.)

Symbiote Spider-Man

Whenever this creature deals combat damage to a player, look at that many cards from the top of your library. Put one of them into your hand and the rest into your graveyard.
Find New Host — {2}{U/B}, Exile this card from your graveyard: Put a +1/+1 counter on target creature you control. It gains this card's other abilities. Activate only as a sorcery.

Evolving Wilds

{T}, Sacrifice this land: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.

Vibrant Cityscape

Venomized Cat

Deathtouch
When this creature enters, mill two cards. (Put the top two cards of your library into your graveyard.)

Behold the Sinister Six!

Return up to six target creature cards with different names from your graveyard to the battlefield.

Superior Spider-Man

Mind Swap — You may have Superior Spider-Man enter as a copy of any creature card in a graveyard, except his name is Superior Spider-Man and he's a 4/4 Spider Human Hero in addition to his other types. When you do, exile that card.

Sinister Hideout

This land enters tapped.
{T}: Add {U} or {B}.
{4}, {T}: Surveil 1. (Look at the top card of your library. You may put it into your graveyard.)

Tombstone, Career Criminal

When Tombstone enters, return target Villain card from your graveyard to your hand.
Villain spells you cast cost {1} less to cast.

Unsummon

Return target creature to its owner's hand.

Swarm, Being of Bees

Flash
Flying
Mayhem {B} (You may cast this card from your graveyard for {B} if you discarded it this turn. Timing rules still apply.)

Raging Goblinoids

Haste
Mayhem {2}{R} (You may cast this card from your graveyard for {2}{R} if you discarded it this turn. Timing rules still apply.)

Spider-Man No More

Enchant creature
Enchanted creature is a Citizen with base power and toughness 1/1. It has defender and loses all other abilities. (It also loses all other creature types.)

Gwenom, Remorseless

Deathtouch, lifelink
Whenever Gwenom attacks, until end of turn, you may look at the top card of your library any time and you may play cards from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.

Spider-Man Noir

Menace
Whenever a creature you control attacks alone, put a +1/+1 counter on it. Then surveil X, where X is the number of counters on it. (Look at the top X cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Rite of Replication

Kicker {5} (You may pay an additional {5} as you cast this spell.)
Create a token that's a copy of target creature. If this spell was kicked, create five of those tokens instead.

The Spot's Portal

Put target creature on the bottom of its owner's library. You lose 2 life unless you control a Villain.

Rocket-Powered Goblin Glider

When this Equipment enters, if it was cast from your graveyard, attach it to target creature you control.
Equipped creature gets +2/+0 and has flying and haste.
Equip {2}
Mayhem {2}

Mysterio's Phantasm

Flying, vigilance
Whenever this creature attacks, mill a card. (Put the top card of your library into your graveyard.)

Arcane Signet

Whoosh!

Kicker {1}{U} (You may pay an additional {1}{U} as you cast this spell.)
Return target nonland permanent to its owner's hand. If this spell was kicked, draw a card.

Green Goblin, Revenant

Flying, deathtouch
Whenever Green Goblin attacks, discard a card. Then draw a card for each card you've discarded this turn.

Frantic Search

Draw two cards, then discard two cards. Untap up to three lands.

Cathartic Pyre

Choose one —
• Cathartic Pyre deals 3 damage to target creature or planeswalker.
• Discard up to two cards, then draw that many cards.

Scarlet Spider, Kaine

Menace (This creature can't be blocked except by two or more creatures.)
When Scarlet Spider enters, you may discard a card. If you do, put a +1/+1 counter on him.
Mayhem {B/R} (You may cast this card from your graveyard for {B/R} if you discarded it this turn. Timing rules still apply.)

School Daze

Choose one —
• Do Homework — Draw three cards.
• Fight Crime — Counter target spell. Draw a card.

Venom's Hunger

This spell costs {2} less to cast if you control a Villain.
Destroy target creature. You gain 2 life.

Doc Ock, Sinister Scientist

As long as there are eight or more cards in your graveyard, Doc Ock has base power and toughness 8/8.
As long as you control another Villain, Doc Ock has hexproof. (He can't be the target of spells or abilities your opponents control.)