Orzhov Signet

Fellwar Stone

{T}: Add one mana of any color that a land an opponent controls could produce.

Rush of Dread

Spree (Choose one or more additional costs.)
+ {1} — Target opponent sacrifices half the creatures they control of their choice, rounded up.
+ {2} — Target opponent discards half the cards in their hand, rounded up.
+ {2} — Target opponent loses half their life, rounded up.

Conjurer's Closet

At the beginning of your end step, you may exile target creature you control, then return that card to the battlefield under your control.

Flickerwisp

Flying
When this creature enters, exile another target permanent. Return that card to the battlefield under its owner's control at the beginning of the next end step.

Doom Whisperer

Flying, trample
Pay 2 life: Surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Soul Warden

Whenever another creature enters, you gain 1 life.

Pact Weapon

As long as this Equipment is attached to a creature, you don't lose the game for having 0 or less life.
Whenever equipped creature attacks, draw a card and reveal it. The creature gets +X/+X until end of turn and you lose X life, where X is that card's mana value.
Equip—Discard a card.

Night's Whisper

Mister Negative

Vigilance, lifelink
Darkforce Inversion — When Mister Negative enters, you may exchange life totals with target opponent. If you lost life this way, draw that many cards.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Godless Shrine

({T}: Add {W} or {B}.)
As this land enters, you may pay 2 life. If you don't, it enters tapped.

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Command Beacon

{T}: Add {C}.
{T}, Sacrifice this land: Put your commander into your hand from the command zone.

City of Brass

Whenever this land becomes tapped, it deals 1 damage to you.
{T}: Add one mana of any color.

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Mana Confluence

{T}, Pay 1 life: Add one mana of any color.

Damn

Destroy target creature. A creature destroyed this way can't be regenerated.
Overload {2}{W}{W} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Plains

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Dark Ritual

Ephemerate

Exile target creature you control, then return it to the battlefield under its owner's control.
Rebound (If you cast this spell from your hand, exile it as it resolves. At the beginning of your next upkeep, you may cast this card from exile without paying its mana cost.)

Vault of the Archangel

{T}: Add {C}.
{2}{W}{B}, {T}: Creatures you control gain deathtouch and lifelink until end of turn.

Land Tax

At the beginning of your upkeep, if an opponent controls more lands than you, you may search your library for up to three basic land cards, reveal them, put them into your hand, then shuffle.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Caves of Koilos

{T}: Add {C}.
{T}: Add {W} or {B}. This land deals 1 damage to you.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Talisman of Hierarchy

{T}: Add {C}.
{T}: Add {W} or {B}. This artifact deals 1 damage to you.

Arid Mesa

{T}, Pay 1 life, Sacrifice this land: Search your library for a Mountain or Plains card, put it onto the battlefield, then shuffle.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Eerie Interlude

Exile any number of target creatures you control. Return those cards to the battlefield under their owner's control at the beginning of the next end step.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Lotho, Corrupt Shirriff

Whenever a player casts their second spell each turn, you lose 1 life and create a Treasure token. (It's an artifact with "{T}, Sacrifice this token: Add one mana of any color.")

Shard of the Nightbringer

Flying
Drain Life — When this creature enters, if you cast it, target opponent loses half their life, rounded up. You gain life equal to the life lost this way.

Black Market Connections

At the beginning of your first main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It is every creature type.)

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Thran Dynamo

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Polluted Delta

{T}, Pay 1 life, Sacrifice this land: Search your library for an Island or Swamp card, put it onto the battlefield, then shuffle.

Vault of Champions

This land enters tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Dark Confidant

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Ad Nauseam

Reveal the top card of your library and put that card into your hand. You lose life equal to its mana value. You may repeat this process any number of times.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Bleachbone Verge

{T}: Add {B}.
{T}: Add {W}. Activate only if you control a Plains or a Swamp.

Gray Merchant of Asphodel

When this creature enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Greed

Prismatic Vista

{T}, Pay 1 life, Sacrifice this land: Search your library for a basic land card, put it onto the battlefield, then shuffle.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Pearl Medallion

White spells you cast cost {1} less to cast.

Marsh Flats

{T}, Pay 1 life, Sacrifice this land: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Plague Drone

Flying
Rot Fly — If an opponent would gain life, that player loses that much life instead.

Cloudshift

Exile target creature you control, then return that card to the battlefield under your control.

Tainted Remedy

If an opponent would gain life, that player loses that much life instead.

Swamp

Decanter of Endless Water

You have no maximum hand size.
{T}: Add one mana of any color.

War Room

{T}: Add {C}.
{3}, {T}, Pay life equal to the number of colors in your commanders' color identity: Draw a card.

Castle Locthwain

This land enters tapped unless you control a Swamp.
{T}: Add {B}.
{1}{B}{B}, {T}: Draw a card, then you lose life equal to the number of cards in your hand.

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to that card's mana value.

Flare of Fortitude

You may sacrifice a nontoken white creature rather than pay this spell's mana cost.
Until end of turn, your life total can't change, and permanents you control gain hexproof and indestructible.

Sol Ring

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Isolated Chapel

This land enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Mind Stone

{T}: Add {C}.
{1}, {T}, Sacrifice this artifact: Draw a card.

Sign in Blood

Target player draws two cards and loses 2 life.

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Fetid Heath

{T}: Add {C}.
{W/B}, {T}: Add {W}{W}, {W}{B}, or {B}{B}.

Takenuma, Abandoned Mire

{T}: Add {B}.
Channel — {3}{B}, Discard this card: Mill three cards, then return a creature or planeswalker card from your graveyard to your hand. This ability costs {1} less to activate for each legendary creature you control.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Enduring Tenacity

Whenever you gain life, target opponent loses that much life.
When Enduring Tenacity dies, if it was a creature, return it to the battlefield under its owner's control. It's an enchantment. (It's not a creature.)

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Thought Vessel

Ancient Tomb

{T}: Add {C}{C}. This land deals 2 damage to you.

Bloodthirsty Conqueror

Flying, deathtouch
Whenever an opponent loses life, you gain that much life. (Damage causes loss of life.)

Arcane Signet

Scrubland

Cliffhaven Vampire

Flying
Whenever you gain life, each opponent loses 1 life.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Knight of the White Orchid

First strike
When this creature enters, if an opponent controls more lands than you, you may search your library for a Plains card, put it onto the battlefield, then shuffle.

Jet Medallion

Black spells you cast cost {1} less to cast.

Starscape Cleric

Offspring {2}{B} (You may pay an additional {2}{B} as you cast this spell. If you do, when this creature enters, create a 1/1 token copy of it.)
Flying
This creature can't block.
Whenever you gain life, each opponent loses 1 life.