Contaminated Bond

Enchant creature (Target a creature as you cast this. This card enters attached to that creature.)
Whenever enchanted creature attacks or blocks, its controller loses 3 life.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)

Bile Urchin

Sacrifice this creature: Target player loses 1 life.

Essence Harvest

Target player loses X life and you gain X life, where X is the greatest power among creatures you control.

Changeling Outcast

Changeling (This card is every creature type.)
This creature can't block and can't be blocked.

Universal Automaton

Changeling (This card is every creature type.)

Call for Blood

As an additional cost to cast this spell, sacrifice a creature.
Target creature gets -X/-X until end of turn, where X is the sacrificed creature's power.

Syphon Life

Target player loses 2 life and you gain 2 life.
Retrace (You may cast this card from your graveyard by discarding a land card in addition to paying its other costs.)

Soul Reap

Destroy target nongreen creature. Its controller loses 3 life if you've cast another black spell this turn.

Horobi's Whisper

If you control a Swamp, destroy target nonblack creature.
Splice onto Arcane—Exile four cards from your graveyard. (As you cast an Arcane spell, you may reveal this card from your hand and pay its splice cost. If you do, add this card's effects to that spell.)

Fruit of Tizerus

Target player loses 2 life.
Escape—{3}{B}, Exile three other cards from your graveyard. (You may cast this card from your graveyard for its escape cost.)

Gray Merchant of Asphodel

When this creature enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Spirit of Malevolence

When this creature dies, each opponent loses 1 life and you gain 1 life.

Piranha Marsh

This land enters tapped.
When this land enters, target player loses 1 life.
{T}: Add {B}.

Waking Nightmare

Falkenrath Noble

Flying
Whenever this creature or another creature dies, target player loses 1 life and you gain 1 life.

Sovereign's Bite

Target player loses 3 life and you gain 3 life.

Blood Tithe

Each opponent loses 3 life. You gain life equal to the life lost this way.

Gruesome Fate

Each opponent loses 1 life for each creature you control.

Kami of the Waning Moon

Flying
Whenever you cast a Spirit or Arcane spell, target creature gains fear until end of turn. (It can't be blocked except by artifact creatures and/or black creatures.)

Dogged Pursuit

At the beginning of your end step, each opponent loses 1 life and you gain 1 life.

Vampire's Kiss

Target player loses 2 life and you gain 2 life. Create two Blood tokens. (They're artifacts with "{1}, {T}, Discard a card, Sacrifice this token: Draw a card.")

Death of a Thousand Stings

Target player loses 1 life and you gain 1 life.
At the beginning of your upkeep, if you have more cards in hand than each opponent, you may return this card from your graveyard to your hand.

Crushing Disappointment

Each player loses 2 life. You draw two cards.

Trespasser's Curse

Enchant player
Whenever a creature enchanted player controls enters, that player loses 1 life and you gain 1 life.

Stab Wound

Enchant creature
Enchanted creature gets -2/-2.
At the beginning of the upkeep of enchanted creature's controller, that player loses 2 life.

Kami of Empty Graves

Soulshift 3 (When this creature dies, you may return target Spirit card with mana value 3 or less from your graveyard to your hand.)

Withercrown

Enchant creature
Enchanted creature has base power 0 and has "At the beginning of your upkeep, you lose 1 life unless you sacrifice this creature."

Geth's Verdict

Target player sacrifices a creature of their choice and loses 1 life.

Scion of Ugin

Thief of Hope

Whenever you cast a Spirit or Arcane spell, target opponent loses 1 life and you gain 1 life.
Soulshift 2 (When this creature dies, you may return target Spirit card with mana value 2 or less from your graveyard to your hand.)

Accursed Spirit

Intimidate (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)

Barkform Harvester

Changeling (This card is every creature type.)
Reach
{2}: Put target card from your graveyard on the bottom of your library.

Ashen-Skin Zubera

When this creature dies, target opponent discards a card for each Zubera that died this turn.

Deathknell Kami

Flying
{2}: This creature gets +1/+1 until end of turn. Sacrifice it at the beginning of the next end step.
Soulshift 1 (When this creature dies, you may return target Spirit card with mana value 1 or less from your graveyard to your hand.)

Hideous End

Destroy target nonblack creature. Its controller loses 2 life.

Urborg Syphon-Mage

{2}{B}, {T}, Discard a card: Each other player loses 2 life. You gain life equal to the life lost this way.

Scuttling Death

Sacrifice this creature: Target creature gets -1/-1 until end of turn.
Soulshift 4 (When this creature dies, you may return target Spirit card with mana value 4 or less from your graveyard to your hand.)

Plagued Rusalka

{B}, Sacrifice a creature: Target creature gets -1/-1 until end of turn.

Soulless Revival

Return target creature card from your graveyard to your hand.
Splice onto Arcane {1}{B} (As you cast an Arcane spell, you may reveal this card from your hand and pay its splice cost. If you do, add this card's effects to that spell.)

Consuming Sepulcher

At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Tithing Blade

When this artifact enters, each opponent sacrifices a creature of their choice.
Craft with creature {4}{B} ({4}{B}, Exile this artifact, Exile a creature you control or a creature card from your graveyard: Return this card transformed under its owner's control. Craft only as a sorcery.)

Tithing Blade // Consuming Sepulcher

Banewasp Affliction

Enchant creature
When enchanted creature dies, that creature's controller loses life equal to its toughness.

Sign in Blood

Target player draws two cards and loses 2 life.

Vermin Gorger

{T}, Sacrifice another creature: Each opponent loses 2 life and you gain 2 life.

Essence Feed

Target player loses 3 life. You gain 3 life and create three 0/1 colorless Eldrazi Spawn creature tokens. They have "Sacrifice this token: Add {C}."

Wicked Akuba

{B}: Target player dealt damage by this creature this turn loses 1 life.

Tattered Mummy

When this creature dies, each opponent loses 2 life.

Vendetta

Destroy target nonblack creature. It can't be regenerated. You lose life equal to that creature's toughness.

Succumb to Temptation

Risky Shortcut

Draw two cards. Each player loses 2 life.

Devouring Greed

As an additional cost to cast this spell, you may sacrifice any number of Spirits.
Target player loses 2 life plus 2 life for each Spirit sacrificed this way. You gain that much life.

Disowned Ancestor

Outlast {1}{B} ({1}{B}, {T}: Put a +1/+1 counter on this creature. Outlast only as a sorcery.)

Gibbering Kami

Flying
Soulshift 3 (When this creature dies, you may return target Spirit card with mana value 3 or less from your graveyard to your hand.)

Contaminated Ground

Enchant land
Enchanted land is a Swamp.
Whenever enchanted land becomes tapped, its controller loses 2 life.

Rend Flesh

Dread Rider

{1}{B}, {T}, Exile a creature card from your graveyard: Target opponent loses 3 life.

Stronghold Discipline

Each player loses 1 life for each creature they control.

Nameless Inversion

Changeling (This card is every creature type.)
Target creature gets +3/-3 and loses all creature types until end of turn.

Death Denied

Return X target creature cards from your graveyard to your hand.

Tormented Soul

This creature can't block and can't be blocked.

Echo of Dusk

Descend 4 — As long as there are four or more permanent cards in your graveyard, this creature gets +1/+1 and has lifelink.

Venomous Changeling

Changeling (This card is every creature type.)
Deathtouch

Blood Pact

Blood Seeker

Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Kami of Jealous Thirst

Deathtouch
{4}{B}: Each opponent loses 2 life and you gain 2 life. This ability costs {4}{B} less to activate if you've drawn three or more cards this turn. Activate only once each turn.

Shadow Slice

Target opponent loses 3 life.
Cipher (Then you may exile this spell card encoded on a creature you control. Whenever that creature deals combat damage to a player, its controller may cast a copy of the encoded card without paying its mana cost.)

Crawling Filth

Fear (This creature can't be blocked except by artifact creatures and/or black creatures.)
Soulshift 5 (When this creature dies, you may return target Spirit card with mana value 5 or less from your graveyard to your hand.)