Plague Drone

Flying
Rot Fly — If an opponent would gain life, that player loses that much life instead.

Great Unclean One

Reverberating Summons — At the beginning of your end step, each opponent loses 2 life. Then for each opponent who has less life than you, create a 1/3 black Demon creature token named Plaguebearer of Nurgle.

Rakdos, Patron of Chaos

Flying, trample
At the beginning of your end step, target opponent may sacrifice two nonland, nontoken permanents of their choice. If they don't, you draw two cards.

Herald of Slaanesh

Locus of Slaanesh — Demon spells you cast cost {2} less to cast.
Other Demons you control have haste.

Valgavoth, Harrower of Souls

Flying
Ward—Pay 2 life.
Whenever an opponent loses life for the first time during each of their turns, put a +1/+1 counter on Valgavoth and draw a card.

Bloodthirster

Flying, trample
Whenever this creature deals combat damage to a player, untap it. After this phase, there is an additional combat phase.
This creature can't attack a player it has already attacked this turn.

Lord of Change

Flying, ward {3}
Architect of Deception — When this creature enters, draw three cards.

Starfield Vocalist

If a permanent entering the battlefield causes a triggered ability of a permanent you control to trigger, that ability triggers an additional time.
Warp {1}{U} (You may cast this card from your hand for its warp cost. Exile this creature at the beginning of the next end step, then you may cast it from exile on a later turn.)

Be'lakor, the Dark Master

Flying
Prince of Chaos — When Be'lakor, the Dark Master enters, you draw X cards and you lose X life, where X is the number of Demons you control.
Lord of Torment — Whenever another Demon you control enters, it deals damage equal to its power to any target.

Karlach, Fury of Avernus

Whenever you attack, if it's the first combat phase of the turn, untap all attacking creatures. They gain first strike until end of turn. After this phase, there is an additional combat phase.
Choose a Background (You can have a Background as a second commander.)