Quest for the Nihil Stone

Whenever an opponent discards a card, you may put a quest counter on Quest for the Nihil Stone.
At the beginning of each opponent's upkeep, if that player has no cards in hand and Quest for the Nihil Stone has two or more quest counters on it, you may have that player lose 5 life.

Nihilistic Glee

{2}{B}, Discard a card: Target opponent loses 1 life and you gain 1 life.
Hellbent — {1}, Pay 2 life: Draw a card. Activate only if you have no cards in hand.

Malevolent Whispers

Gain control of target creature until end of turn. Untap that creature. It gets +2/+0 and gains haste until end of turn.
Madness {3}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Shattered Perception

Discard all the cards in your hand, then draw that many cards.
Flashback {5}{R} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Bloodmad Vampire

Whenever Bloodmad Vampire deals combat damage to a player, put a +1/+1 counter on it.
Madness {1}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Tortured Existence

{B}, Discard a creature card: Return target creature card from your graveyard to your hand.

Gibbering Descent

At the beginning of each player's upkeep, that player loses 1 life and discards a card.
Hellbent — Skip your upkeep step if you have no cards in hand.
Madness {2}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Markov Dreadknight

Flying
{2}{B}, Discard a card: Put two +1/+1 counters on Markov Dreadknight.

Insatiable Gorgers

Insatiable Gorgers attacks each combat if able.
Madness {3}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Ichor Slick

Target creature gets -3/-3 until end of turn.
Cycling {2} ({2}, Discard this card: Draw a card.)
Madness {3}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Collective Brutality

Escalate—Discard a card. (Pay this cost for each mode chosen beyond the first.)
Choose one or more —
• Target opponent reveals their hand. You choose an instant or sorcery card from it. That player discards that card.
• Target creature gets -2/-2 until end of turn.
• Target opponent loses 2 life and you gain 2 life.

Gisa's Bidding

Create two 2/2 black Zombie creature tokens.
Madness {2}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Ravenous Bloodseeker

Discard a card: Ravenous Bloodseeker gets +2/-2 until end of turn.

Falkenrath Gorger

Each Vampire creature card you own that isn't on the battlefield has madness. The madness cost is equal to its mana cost. (If you discard a card with madness, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Markov Blademaster

Double strike (This creature deals both first-strike and regular combat damage.)
Whenever Markov Blademaster deals combat damage to a player, put a +1/+1 counter on it.

Faithless Looting

Draw two cards, then discard two cards.
Flashback {2}{R} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Sire of Insanity

At the beginning of each end step, each player discards their hand.

Reckless Wurm

Trample
Madness {2}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Gamble

Search your library for a card, put that card into your hand, discard a card at random, then shuffle.

Squee, Goblin Nabob

At the beginning of your upkeep, you may return Squee, Goblin Nabob from your graveyard to your hand.

Cathartic Reunion

As an additional cost to cast this spell, discard two cards.
Draw three cards.

Bloodhusk Ritualist

Multikicker {B} (You may pay an additional {B} any number of times as you cast this spell.)
When Bloodhusk Ritualist enters, target opponent discards a card for each time it was kicked.

Nahiri's Wrath

As an additional cost to cast this spell, discard X cards.
Nahiri's Wrath deals damage equal to the total mana value of the discarded cards to each of up to X target creatures and/or planeswalkers.

Stromkirk Occultist

Trample
Whenever Stromkirk Occultist deals combat damage to a player, exile the top card of your library. Until end of turn, you may play that card.
Madness {1}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Necrogen Mists

At the beginning of each player's upkeep, that player discards a card.

Mindstorm Crown

At the beginning of your upkeep, draw a card if you had no cards in hand at the beginning of this turn. If you had a card in hand, Mindstorm Crown deals 1 damage to you.

Runehorn Hellkite

Flying
{5}{R}, Exile Runehorn Hellkite from your graveyard: Each player discards their hand, then draws seven cards.

Incorrigible Youths

Haste (This creature can attack and {T} as soon as it comes under your control.)
Madness {2}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Avacyn's Judgment

Madness {X}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)
Avacyn's Judgment deals 2 damage divided as you choose among any number of targets. If this spell's madness cost was paid, it deals X damage divided as you choose among those permanents and/or players instead.

Faith of the Devoted

Whenever you cycle or discard a card, you may pay {1}. If you do, each opponent loses 2 life and you gain 2 life.

Stensia Masquerade

Attacking creatures you control have first strike.
Whenever a Vampire you control deals combat damage to a player, put a +1/+1 counter on it.
Madness {2}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Tormenting Voice

As an additional cost to cast this spell, discard a card.
Draw two cards.

Haakon, Stromgald Scourge

You may cast Haakon, Stromgald Scourge from your graveyard, but not from anywhere else.
As long as Haakon is on the battlefield, you may cast Knight spells from your graveyard.
When Haakon dies, you lose 2 life.

Glint-Horn Buccaneer

Haste
Whenever you discard a card, Glint-Horn Buccaneer deals 1 damage to each opponent.
{1}{R}, Discard a card: Draw a card. Activate only if Glint-Horn Buccaneer is attacking.

Geier Reach Sanitarium

{T}: Add {C}.
{2}, {T}: Each player draws a card, then discards a card.

Grave Scrabbler

Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)
When Grave Scrabbler enters, if its madness cost was paid, you may return target creature card from a graveyard to its owner's hand.

Chandra Ablaze

+1: Discard a card. If a red card is discarded this way, Chandra Ablaze deals 4 damage to any target.
−2: Each player discards their hand, then draws three cards.
−7: Cast any number of red instant and/or sorcery cards from your graveyard without paying their mana costs.

Gate to the Afterlife

Whenever a nontoken creature you control dies, you gain 1 life. Then you may draw a card. If you do, discard a card.
{2}, {T}, Sacrifice Gate to the Afterlife: Search your graveyard, hand, and/or library for a card named God-Pharaoh's Gift and put it onto the battlefield. If you search your library this way, shuffle. Activate only if there are six or more creature cards in your graveyard.

Chain of Smog

Target player discards two cards. That player may copy this spell and may choose a new target for that copy.

Heir to the Night

Heir of Falkenrath

Discard a card: Transform Heir of Falkenrath. Activate only once each turn.

Heir of Falkenrath // Heir to the Night

Call the Bloodline

{1}, Discard a card: Create a 1/1 black Vampire Knight creature token with lifelink. Activate only once each turn.

Muck Drubb

Flash
When Muck Drubb enters, change the target of target spell that targets only a single creature to Muck Drubb.
Madness {2}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Nightshade Assassin

First strike
When Nightshade Assassin enters, you may reveal X black cards in your hand. If you do, target creature gets -X/-X until end of turn.
Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Mind Rake

Target player discards two cards.
Overload {1}{B} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Throes of Chaos

Cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)
Retrace (You may cast this card from your graveyard by discarding a land card in addition to paying its other costs.)

Twins of Maurer Estate

Madness {2}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Archfiend of Ifnir

Flying
Whenever you cycle or discard another card, put a -1/-1 counter on each creature your opponents control.
Cycling {2} ({2}, Discard this card: Draw a card.)

Stromkirk Condemned

Discard a card: Vampires you control get +1/+1 until end of turn. Activate only once each turn.

Key to the City

{T}, Discard a card: Up to one target creature can't be blocked this turn.
Whenever Key to the City becomes untapped, you may pay {2}. If you do, draw a card.

Weirded Vampire

Hazoret's Monument

Red creature spells you cast cost {1} less to cast.
Whenever you cast a creature spell, you may discard a card. If you do, draw a card.

Creeping Dread

At the beginning of your upkeep, each player discards a card. Each opponent who discarded a card that shares a card type with the card you discarded loses 3 life. (Players reveal the discarded cards simultaneously.)

Insolent Neonate

Menace (This creature can't be blocked except by two or more creatures.)
Discard a card, Sacrifice Insolent Neonate: Draw a card.

Asylum Visitor

At the beginning of each player's upkeep, if that player has no cards in hand, you draw a card and you lose 1 life.
Madness {1}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Anger

Haste
As long as Anger is in your graveyard and you control a Mountain, creatures you control have haste.

Bloodhall Priest

Whenever Bloodhall Priest enters or attacks, if you have no cards in hand, Bloodhall Priest deals 2 damage to any target.
Madness {1}{B}{R} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Olivia, Mobilized for War

Flying
Whenever another creature you control enters, you may discard a card. If you do, put a +1/+1 counter on that creature, it gains haste until end of turn, and it becomes a Vampire in addition to its other types.

Syphon Mind

Each other player discards a card. You draw a card for each card discarded this way.

Abolisher of Bloodlines

Flying
When this creature transforms into Abolisher of Bloodlines, target opponent sacrifices three creatures of their choice.

Voldaren Pariah

Flying
Sacrifice three other creatures: Transform Voldaren Pariah.
Madness {B}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Voldaren Pariah // Abolisher of Bloodlines

Decaying Soil

At the beginning of your upkeep, exile a card from your graveyard.
Threshold — As long as seven or more cards are in your graveyard, Decaying Soil has "Whenever a nontoken creature is put into your graveyard from the battlefield, you may pay {1}. If you do, return that card to your hand."

Blood Scrivener

If you would draw a card while you have no cards in hand, instead you draw two cards and you lose 1 life.

Rix Maadi, Dungeon Palace

{T}: Add {C}.
{1}{B}{R}, {T}: Each player discards a card. Activate only as a sorcery.

Furyblade Vampire

Trample
At the beginning of combat on your turn, you may discard a card. If you do, Furyblade Vampire gets +3/+0 until end of turn.

Indulgent Aristocrat

Lifelink
{2}, Sacrifice a creature: Put a +1/+1 counter on each Vampire you control.

Hollowborn Barghest

At the beginning of your upkeep, if you have no cards in hand, each opponent loses 2 life.
At the beginning of each opponent's upkeep, if that player has no cards in hand, they lose 2 life.

Cunning Lethemancer

At the beginning of your upkeep, each player discards a card.

Waste Not

Whenever an opponent discards a creature card, create a 2/2 black Zombie creature token.
Whenever an opponent discards a land card, add {B}{B}.
Whenever an opponent discards a noncreature, nonland card, draw a card.

The Haunt of Hightower

Flying, lifelink
Whenever The Haunt of Hightower attacks, defending player discards a card.
Whenever a card is put into an opponent's graveyard from anywhere, put a +1/+1 counter on The Haunt of Hightower.

Shred Memory

Exile up to four target cards from a single graveyard.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Dark Withering

Destroy target nonblack creature.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Geth's Grimoire

Whenever an opponent discards a card, you may draw a card.

Cavalier of Flame

{1}{R}: Creatures you control get +1/+0 and gain haste until end of turn.
When Cavalier of Flame enters, discard any number of cards, then draw that many cards.
When Cavalier of Flame dies, it deals X damage to each opponent and each planeswalker they control, where X is the number of land cards in your graveyard.

Hazoret the Fervent

Indestructible, haste
Hazoret the Fervent can't attack or block unless you have one or fewer cards in hand.
{2}{R}, Discard a card: Hazoret deals 2 damage to each opponent.

Bottomless Pit

At the beginning of each player's upkeep, that player discards a card at random.

Azra Oddsmaker

At the beginning of combat on your turn, you may discard a card. If you do, choose a creature. Whenever that creature deals combat damage to a player this turn, you draw two cards.

Big Game Hunter

When Big Game Hunter enters, destroy target creature with power 4 or greater. It can't be regenerated.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)