Bladegriff Prototype

Flying
Whenever Bladegriff Prototype deals combat damage to a player, destroy target nonland permanent of that player's choice that one of your opponents controls.

Lurking Deadeye

Flash
When Lurking Deadeye enters the battlefield, destroy target creature that was dealt damage this turn.

Finishing Blow

In Garruk's Wake

Destroy all creatures you don't control and all planeswalkers you don't control.

Irreverent Revelers

When Irreverent Revelers enters the battlefield, choose one —
• Destroy target artifact.
• Irreverent Revelers gains haste until end of turn.

Silumgar Assassin

Creatures with power greater than Silumgar Assassin's power can't block it.
Megamorph {2}{B} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its megamorph cost and put a +1/+1 counter on it.)
When Silumgar Assassin is turned face up, destroy target creature with power 3 or less an opponent controls.

Encroaching Wastes

{T}: Add {C}.
{4}, {T}, Sacrifice Encroaching Wastes: Destroy target nonbasic land.

Overseer of the Damned

Flying
When Overseer of the Damned enters the battlefield, you may destroy target creature.
Whenever a nontoken creature an opponent controls dies, create a tapped 2/2 black Zombie creature token.

Annihilate

Destroy target nonblack creature. It can't be regenerated.
Draw a card.

Bedazzle

Destroy target nonbasic land. Bedazzle deals 2 damage to target opponent or planeswalker.

Bedeck

Target creature gets +3/-3 until end of turn.

Bedeck // Bedazzle

Gilt-Leaf Winnower

Menace (This creature can't be blocked except by two or more creatures.)
When Gilt-Leaf Winnower enters the battlefield, you may destroy target non-Elf creature whose power and toughness aren't equal.

Cast Down

Dark Hatchling

Flying
When Dark Hatchling enters the battlefield, destroy target nonblack creature. It can't be regenerated.

Drag to the Underworld

This spell costs {X} less to cast, where X is your devotion to black. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
Destroy target creature.

Keepsake Gorgon

Deathtouch
{5}{B}{B}: Monstrosity 1. (If this creature isn't monstrous, put a +1/+1 counter on it and it becomes monstrous.)
When Keepsake Gorgon becomes monstrous, destroy target non-Gorgon creature an opponent controls.

Deadly Visit

Destroy target creature.
Surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Demon-Possessed Witch

When this creature transforms into Demon-Possessed Witch, you may destroy target creature.

Kindly Stranger

Delirium — {2}{B}: Transform Kindly Stranger. Activate only if there are four or more card types among cards in your graveyard.

Kindly Stranger // Demon-Possessed Witch

Human Frailty

Swamp

Kroxa, Titan of Death's Hunger

When Kroxa enters the battlefield, sacrifice it unless it escaped.
Whenever Kroxa enters the battlefield or attacks, each opponent discards a card, then each opponent who didn't discard a nonland card this way loses 3 life.
Escape—{B}{B}{R}{R}, Exile five other cards from your graveyard. (You may cast this card from your graveyard for its escape cost.)

Eviscerate

Bone Splinters

As an additional cost to cast this spell, sacrifice a creature.
Destroy target creature.

Bust

Boom

Destroy target land you control and target land you don't control.

Boom // Bust

Bone Shredder

Flying
Echo {2}{B} (At the beginning of your upkeep, if this came under your control since the beginning of your last upkeep, sacrifice it unless you pay its echo cost.)
When Bone Shredder enters the battlefield, destroy target nonartifact, nonblack creature.

Noxious Dragon

Flying
When Noxious Dragon dies, you may destroy target creature with mana value 3 or less.

Elspeth's Nightmare

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Destroy target creature an opponent controls with power 2 or less.
II — Target opponent reveals their hand. You choose a noncreature, nonland card from it. That player discards that card.
III — Exile target opponent's graveyard.

Mage Hunters' Onslaught

Destroy target creature or planeswalker.
Whenever a creature blocks this turn, its controller loses 1 life.

Ogre Siegebreaker

{2}{B}{R}: Destroy target creature that was dealt damage this turn.

Memorial to War

Memorial to War enters the battlefield tapped.
{T}: Add {R}.
{4}{R}, {T}, Sacrifice Memorial to War: Destroy target land.

Blood Curdle

Destroy target creature. Put a menace counter on a creature you control. (It can't be blocked except by two or more creatures.)

Doom Blade

Magus of the Abyss

At the beginning of each player's upkeep, destroy target nonartifact creature that player controls of their choice. It can't be regenerated.

Fathom Fleet Cutthroat

When Fathom Fleet Cutthroat enters the battlefield, destroy target creature an opponent controls that was dealt damage this turn.

Corpsehatch

Destroy target nonblack creature. Create two 0/1 colorless Eldrazi Spawn creature tokens. They have "Sacrifice this creature: Add {C}."

Mountain

Tectonic Edge

{T}: Add {C}.
{1}, {T}, Sacrifice Tectonic Edge: Destroy target nonbasic land. Activate only if an opponent controls four or more lands.

Assassinate

Get the Point

Easy Prey

Destroy target creature with mana value 2 or less.
Cycling {2} ({2}, Discard this card: Draw a card.)

Assassin's Strike

Destroy target creature. Its controller discards a card.

Dark Banishing

Destroy target nonblack creature. It can't be regenerated.

Ghastly Demise

Destroy target nonblack creature if its toughness is less than or equal to the number of cards in your graveyard.

Dark Withering

Destroy target nonblack creature.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Sol Ring

Vengeant Vampire

Lifelink
When Vengeant Vampire dies, destroy target creature an opponent controls and you gain 4 life.

Deathmark

Murder

Lich's Caress

Destroy target creature. You gain 3 life.

Eater of Hope

Flying
{B}, Sacrifice another creature: Regenerate Eater of Hope.
{2}{B}, Sacrifice two other creatures: Destroy target creature.

Jaya Ballard, Task Mage

{R}, {T}, Discard a card: Destroy target blue permanent.
{1}{R}, {T}, Discard a card: Jaya Ballard, Task Mage deals 3 damage to any target. A creature dealt damage this way can't be regenerated this turn.
{5}{R}{R}, {T}, Discard a card: Jaya Ballard deals 6 damage to each creature and each player.

Daring Demolition

Jarl of the Forsaken

Flash
When Jarl of the Forsaken enters the battlefield, destroy target creature or planeswalker an opponent controls that was dealt damage this turn.
Foretell {1}{B} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Demolish

Consign to the Pit

Destroy target creature. Consign to the Pit deals 2 damage to that creature's controller.

Deface

Choose one —
• Destroy target artifact.
• Destroy target creature with defender.

Grisly Spectacle

Destroy target nonartifact creature. Its controller mills cards equal to that creature's power.

Certain Death

Destroy target creature. Its controller loses 2 life and you gain 2 life.

Meteor Golem

When Meteor Golem enters the battlefield, destroy target nonland permanent an opponent controls.

Nekrataal

First strike
When Nekrataal enters the battlefield, destroy target nonartifact, nonblack creature. That creature can't be regenerated.

Ravenous Chupacabra

When Ravenous Chupacabra enters the battlefield, destroy target creature an opponent controls.

Goblin Cratermaker

{1}, Sacrifice Goblin Cratermaker: Choose one —
• Goblin Cratermaker deals 2 damage to target creature.
• Destroy target colorless nonland permanent.

Contract Killing

Destroy target creature. Create two Treasure tokens. (They're artifacts with "{T}, Sacrifice this artifact: Add one mana of any color.")

Bake into a Pie

Destroy target creature. Create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")

Loathsome Curator

Exploit (When this creature enters the battlefield, you may sacrifice a creature.)
Menace
When Loathsome Curator exploits a creature, destroy target creature you don't control with mana value 3 or less.

Throat Slitter

Ninjutsu {2}{B} ({2}{B}, Return an unblocked attacker you control to hand: Put this card onto the battlefield from your hand tapped and attacking.)
Whenever Throat Slitter deals combat damage to a player, destroy target nonblack creature that player controls.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Big Game Hunter

When Big Game Hunter enters the battlefield, destroy target creature with power 4 or greater. It can't be regenerated.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Destructive Tampering

Choose one —
• Destroy target artifact.
• Creatures without flying can't block this turn.