Mindsparker

First strike (This creature deals combat damage before creatures without first strike.)
Whenever an opponent casts a white or blue instant or sorcery spell, Mindsparker deals 2 damage to that player.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Mystic Remora

Cumulative upkeep {1} (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
Whenever an opponent casts a noncreature spell, you may draw a card unless that player pays {4}.

Predatory Hunger

Enchant creature
Whenever an opponent casts a creature spell, put a +1/+1 counter on enchanted creature.

Pain Magnification

Whenever an opponent is dealt 3 or more damage by a single source, that player discards a card.

Rhystic Study

Whenever an opponent casts a spell, you may draw a card unless that player pays {1}.

Mind's Dilation

Whenever an opponent casts their first spell each turn, that player exiles the top card of their library. If it's a nonland card, you may cast it without paying its mana cost.

Rest in Peace

When Rest in Peace enters, exile all graveyards.
If a card or token would be put into a graveyard from anywhere, exile it instead.

Kaervek the Merciless

Whenever an opponent casts a spell, Kaervek the Merciless deals damage equal to that spell's mana value to any target.

Immolation Shaman

Whenever an opponent activates an ability of an artifact, creature, or land that isn't a mana ability, Immolation Shaman deals 1 damage to that player.
{3}{R}{R}: Immolation Shaman gets +3/+3 and gains menace until end of turn.

Lavinia, Azorius Renegade

Each opponent can't cast noncreature spells with mana value greater than the number of lands that player controls.
Whenever an opponent casts a spell, if no mana was spent to cast it, counter that spell.

Emberwilde Captain

When Emberwilde Captain enters, you become the monarch.
Whenever an opponent attacks you while you're the monarch, Emberwilde Captain deals damage to that player equal to the number of cards in their hand.

Lone Wolf of the Natterknolls

Whenever an opponent casts a spell during your turn, draw two cards.
At the beginning of each upkeep, if a player cast two or more spells last turn, transform Lone Wolf of the Natterknolls.

Hermit of the Natterknolls

Whenever an opponent casts a spell during your turn, draw a card.
At the beginning of each upkeep, if no spells were cast last turn, transform Hermit of the Natterknolls.

Hermit of the Natterknolls // Lone Wolf of the Natterknolls

Arasta of the Endless Web

Reach
Whenever an opponent casts an instant or sorcery spell, create a 1/2 green Spider creature token with reach.

Kavu Predator

Trample
Whenever an opponent gains life, put that many +1/+1 counters on Kavu Predator.

Nezahal, Primal Tide

This spell can't be countered.
You have no maximum hand size.
Whenever an opponent casts a noncreature spell, draw a card.
Discard three cards: Exile Nezahal, Primal Tide. Return it to the battlefield tapped under its owner's control at the beginning of the next end step.

Mage Hunter

Whenever an opponent casts or copies an instant or sorcery spell, they lose 1 life.

Monologue Tax

Whenever an opponent casts their second spell each turn, you create a Treasure token.

Eyes of the Wisent

Whenever an opponent casts a blue spell during your turn, you may create a 4/4 green Elemental creature token.

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Insight

Whenever an opponent casts a green spell, you draw a card.

Tempting Contract

At the beginning of your upkeep, each opponent may create a Treasure token. For each opponent who does, you create a Treasure token.

Ever-Watching Threshold

Whenever an opponent attacks, if they attacked you and/or a planeswalker you control, draw a card.

Mangara, the Diplomat

Lifelink
Whenever an opponent attacks with creatures, if two or more of those creatures are attacking you and/or planeswalkers you control, draw a card.
Whenever an opponent casts their second spell each turn, draw a card.

Dirtcowl Wurm

Whenever an opponent plays a land, put a +1/+1 counter on Dirtcowl Wurm.

Isolation Cell

Whenever an opponent casts a creature spell, that player loses 2 life unless they pay {2}.

Dragonlair Spider

Reach
Whenever an opponent casts a spell, create a 1/1 green Insect creature token.

Rewards of Diversity

Whenever an opponent casts a multicolored spell, you gain 4 life.

Psychic Surgery

Whenever an opponent shuffles their library, you may look at the top two cards of that library. You may exile one of those cards. Then put the rest on top of that library in any order.

Lurking Predators

Whenever an opponent casts a spell, reveal the top card of your library. If it's a creature card, put it onto the battlefield. Otherwise, you may put that card on the bottom of your library.

Ichneumon Druid

Whenever an opponent casts an instant spell other than the first instant spell that player casts each turn, Ichneumon Druid deals 4 damage to that player.

Raiders' Wake

Whenever an opponent discards a card, that player loses 2 life.
Raid — At the beginning of your end step, if you attacked this turn, target opponent discards a card.

Ruric Thar, the Unbowed

Vigilance, reach
Ruric Thar, the Unbowed attacks each combat if able.
Whenever a player casts a noncreature spell, Ruric Thar deals 6 damage to that player.

Mindcrank

Whenever an opponent loses life, that player mills that many cards. (Damage causes loss of life.)

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Esper Sentinel

Whenever an opponent casts their first noncreature spell each turn, draw a card unless that player pays {X}, where X is Esper Sentinel's power.

Burgeoning

Whenever an opponent plays a land, you may put a land card from your hand onto the battlefield.

Sol Ring

Harsh Mentor

Whenever an opponent activates an ability of an artifact, creature, or land on the battlefield, if it isn't a mana ability, Harsh Mentor deals 2 damage to that player.

Cindervines

Whenever an opponent casts a noncreature spell, Cindervines deals 1 damage to that player.
{1}, Sacrifice Cindervines: Destroy target artifact or enchantment. Cindervines deals 2 damage to that permanent's controller.

Reparations

Whenever an opponent casts a spell that targets you or a creature you control, you may draw a card.

Runic Armasaur

Whenever an opponent activates an ability of a creature or land that isn't a mana ability, you may draw a card.