Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Ob Nixilis, the Fallen

Landfall — Whenever a land enters the battlefield under your control, you may have target player lose 3 life. If you do, put three +1/+1 counters on Ob Nixilis, the Fallen.

Erebos, God of the Dead

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
Your opponents can't gain life.
{1}{B}, Pay 2 life: Draw a card.

Sheoldred, Whispering One

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.
At the beginning of each opponent's upkeep, that player sacrifices a creature.

Crushing Disappointment

Each player loses 2 life. You draw two cards.

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Sinister Possession

Enchant creature
Whenever enchanted creature attacks or blocks, its controller loses 2 life.

Tainted Remedy

If an opponent would gain life, that player loses that much life instead.

Bottomless Vault

Bottomless Vault enters the battlefield tapped.
You may choose not to untap Bottomless Vault during your untap step.
At the beginning of your upkeep, if Bottomless Vault is tapped, put a storage counter on it.
{T}, Remove any number of storage counters from Bottomless Vault: Add {B} for each storage counter removed this way.

Withercrown

Enchant creature
Enchanted creature has base power 0 and has "At the beginning of your upkeep, you lose 1 life unless you sacrifice this creature."

Gonti, Lord of Luxury

Deathtouch
When Gonti, Lord of Luxury enters the battlefield, look at the top four cards of target opponent's library, exile one of them face down, then put the rest on the bottom of that library in a random order. You may cast that card for as long as it remains exiled, and mana of any type can be spent to cast that spell.

Cruel Reality

Enchant player
At the beginning of enchanted player's upkeep, that player sacrifices a creature or planeswalker. If the player can't, they lose 5 life.

Dogged Pursuit

At the beginning of your end step, each opponent loses 1 life and you gain 1 life.

Ob Nixilis, the Hate-Twisted

Whenever an opponent draws a card, Ob Nixilis, the Hate-Twisted deals 1 damage to that player.
−2: Destroy target creature. Its controller draws two cards.

Grim Guardian

Constellation — Whenever Grim Guardian or another enchantment enters the battlefield under your control, each opponent loses 1 life.

Ob Nixilis, Unshackled

Flying, trample
Whenever an opponent searches their library, that player sacrifices a creature and loses 10 life.
Whenever another creature dies, put a +1/+1 counter on Ob Nixilis, Unshackled.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Tetzimoc, Primal Death

Deathtouch
{B}, Reveal Tetzimoc, Primal Death from your hand: Put a prey counter on target creature. Activate only during your turn.
When Tetzimoc enters the battlefield, destroy each creature your opponents control with a prey counter on it.

Skymarch Bloodletter

Flying
When Skymarch Bloodletter enters the battlefield, target opponent loses 1 life and you gain 1 life.

Ill-Gotten Inheritance

At the beginning of your upkeep, Ill-Gotten Inheritance deals 1 damage to each opponent and you gain 1 life.
{5}{B}, Sacrifice Ill-Gotten Inheritance: It deals 4 damage to target opponent and you gain 4 life.

Hissing Miasma

Whenever a creature attacks you, its controller loses 1 life.

Eternal Thirst

Enchant creature
Enchanted creature has lifelink and "Whenever a creature an opponent controls dies, put a +1/+1 counter on this creature." (Damage dealt by a creature with lifelink also causes its controller to gain that much life.)

Ayara, First of Locthwain

Whenever Ayara, First of Locthwain or another black creature enters the battlefield under your control, each opponent loses 1 life and you gain 1 life.
{T}, Sacrifice another black creature: Draw a card.

Soul Bleed

Enchant creature
At the beginning of the upkeep of enchanted creature's controller, that player loses 1 life.

Blood Reckoning

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life.

Tymaret, Chosen from Death

Tymaret's toughness is equal to your devotion to black. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
{1}{B}: Exile up to two target cards from graveyards. You gain 1 life for each creature card exiled this way.

Indulgent Tormentor

Flying
At the beginning of your upkeep, draw a card unless target opponent sacrifices a creature or pays 3 life.

Ihsan's Shade

Curse of Fool's Wisdom

Enchant player
Whenever enchanted player draws a card, they lose 2 life and you gain 2 life.
Madness {3}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Feed the Serpent

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Kokusho, the Evening Star

Flying
When Kokusho, the Evening Star dies, each opponent loses 5 life. You gain life equal to the life lost this way.

Torment of Scarabs

Enchant player
At the beginning of enchanted player's upkeep, that player loses 3 life unless they sacrifice a nonland permanent or discard a card.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Aspect of Lamprey

Enchant creature you control
When Aspect of Lamprey enters the battlefield, target opponent discards two cards.
Enchanted creature has lifelink.

Polluted Bonds

Whenever a land enters the battlefield under an opponent's control, that player loses 2 life and you gain 2 life.

Ashling, the Extinguisher

Whenever Ashling, the Extinguisher deals combat damage to a player, choose target creature that player controls. The player sacrifices that creature.

Kiku, Night's Flower

{2}{B}{B}, {T}: Target creature deals damage to itself equal to its power.

Stab Wound

Enchant creature
Enchanted creature gets -2/-2.
At the beginning of the upkeep of enchanted creature's controller, that player loses 2 life.

Annihilate

Destroy target nonblack creature. It can't be regenerated.
Draw a card.

Subversion

At the beginning of your upkeep, each opponent loses 1 life. You gain life equal to the life lost this way.

Josu Vess, Lich Knight

Kicker {5}{B} (You may pay an additional {5}{B} as you cast this spell.)
Menace
When Josu Vess, Lich Knight enters the battlefield, if it was kicked, create eight 2/2 black Zombie Knight creature tokens with menace.

Whip of Erebos

Creatures you control have lifelink.
{2}{B}{B}, {T}: Return target creature card from your graveyard to the battlefield. It gains haste. Exile it at the beginning of the next end step. If it would leave the battlefield, exile it instead of putting it anywhere else. Activate only as a sorcery.

Cao Cao, Lord of Wei

{T}: Target opponent discards two cards. Activate only during your turn, before attackers are declared.

Korlash, Heir to Blackblade

Korlash, Heir to Blackblade's power and toughness are each equal to the number of Swamps you control.
{1}{B}: Regenerate Korlash.
Grandeur — Discard another card named Korlash, Heir to Blackblade: Search your library for up to two Swamp cards, put them onto the battlefield tapped, then shuffle.

Tergrid's Lantern

{T}: Target player loses 3 life unless they sacrifice a nonland permanent or discard a card.
{3}{B}: Untap Tergrid's Lantern.

Tergrid, God of Fright

Menace
Whenever an opponent sacrifices a nontoken permanent or discards a permanent card, you may put that card from a graveyard onto the battlefield under your control.

Tergrid, God of Fright // Tergrid's Lantern

Baneful Omen

At the beginning of your end step, you may reveal the top card of your library. If you do, each opponent loses life equal to that card's mana value.

Geth, Lord of the Vault

Intimidate (This creature can't be blocked except by artifact creatures and/or creatures that share a color with it.)
{X}{B}: Put target artifact or creature card with mana value X from an opponent's graveyard onto the battlefield under your control tapped. Then that player mills X cards.

Trespasser's Curse

Enchant player
Whenever a creature enters the battlefield under enchanted player's control, that player loses 1 life and you gain 1 life.

God-Eternal Bontu

Menace
When God-Eternal Bontu enters the battlefield, sacrifice any number of other permanents, then draw that many cards.
When God-Eternal Bontu dies or is put into exile from the battlefield, you may put it into its owner's library third from the top.

Phyrexian Rager

When Phyrexian Rager enters the battlefield, you draw a card and you lose 1 life.

Unwilling Ingredient

Menace (This creature can't be blocked except by two or more creatures.)
{2}{B}, Exile Unwilling Ingredient from your graveyard: You draw a card and you lose 1 life.

The Haunt of Hightower

Flying, lifelink
Whenever The Haunt of Hightower attacks, defending player discards a card.
Whenever a card is put into an opponent's graveyard from anywhere, put a +1/+1 counter on The Haunt of Hightower.

Urgoros, the Empty One

Flying
Whenever Urgoros, the Empty One deals combat damage to a player, that player discards a card at random. If the player can't, you draw a card.

Dread Presence

Whenever a Swamp enters the battlefield under your control, choose one —
• You draw a card and you lose 1 life.
• Dread Presence deals 2 damage to any target and you gain 2 life.

Palace Siege

As Palace Siege enters the battlefield, choose Khans or Dragons.
• Khans — At the beginning of your upkeep, return target creature card from your graveyard to your hand.
• Dragons — At the beginning of your upkeep, each opponent loses 2 life and you gain 2 life.

Dying Wish

Enchant creature you control
When enchanted creature dies, target player loses X life and you gain X life, where X is its power.

Yahenni, Undying Partisan

Haste
Whenever a creature an opponent controls dies, put a +1/+1 counter on Yahenni, Undying Partisan.
Sacrifice another creature: Yahenni gains indestructible until end of turn.

Pooling Venom

Enchant land
Whenever enchanted land becomes tapped, its controller loses 2 life.
{3}{B}: Destroy enchanted land.

Swamp

Liliana of the Dark Realms

+1: Search your library for a Swamp card, reveal it, put it into your hand, then shuffle.
−3: Target creature gets +X/+X or -X/-X until end of turn, where X is the number of Swamps you control.
−6: You get an emblem with "Swamps you control have '{T}: Add {B}{B}{B}{B}.'"