Sorin, Grim Nemesis

+1: Reveal the top card of your library and put that card into your hand. Each opponent loses life equal to its mana value.
−X: Sorin, Grim Nemesis deals X damage to target creature or planeswalker and you gain X life.
−9: Create a number of 1/1 black Vampire Knight creature tokens with lifelink equal to the highest life total among all players.

Windborn Muse

Flying
Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Authority of the Consuls

Creatures your opponents control enter the battlefield tapped.
Whenever a creature enters the battlefield under an opponent's control, you gain 1 life.

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Sol Ring

Sphere of Safety

Creatures can't attack you or planeswalkers you control unless their controller pays {X} for each of those creatures, where X is the number of enchantments you control.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Deadly Vanity

Choose a creature or planeswalker, then destroy all other creatures and planeswalkers.

Selfless Glyphweaver

Exile Selfless Glyphweaver: Creatures you control gain indestructible until end of turn.

Selfless Glyphweaver // Deadly Vanity

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter the battlefield tapped.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Inkshield

Prevent all combat damage that would be dealt to you this turn. For each 1 damage prevented this way, create a 2/1 white and black Inkling creature token with flying.

Selfless Squire

Flash
When Selfless Squire enters the battlefield, prevent all damage that would be dealt to you this turn.
Whenever damage that would be dealt to you is prevented, put that many +1/+1 counters on Selfless Squire.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Strict Proctor

Flying
Whenever a permanent entering the battlefield causes a triggered ability to trigger, counter that ability unless its controller pays {2}.

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Speaker of the Heavens

Vigilance, lifelink
{T}: Create a 4/4 white Angel creature token with flying. Activate only if you have at least 7 life more than your starting life total and only as a sorcery.

Bloodthirsty Aerialist

Flying
Whenever you gain life, put a +1/+1 counter on Bloodthirsty Aerialist.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Sign in Blood

Target player draws two cards and loses 2 life.

Cleaving Reaper

Flying, trample
Pay 3 life: Return Cleaving Reaper from your graveyard to your hand. Activate only if you had an Angel or Berserker enter the battlefield under your control this turn.

Gift of Immortality

Enchant creature
When enchanted creature dies, return that card to the battlefield under its owner's control. Return Gift of Immortality to the battlefield attached to that creature at the beginning of the next end step.

Selenia, Dark Angel

Flying
Pay 2 life: Return Selenia, Dark Angel to its owner's hand.

Suture Priest

Whenever another creature enters the battlefield under your control, you may gain 1 life.
Whenever a creature enters the battlefield under an opponent's control, you may have that player lose 1 life.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Cosmos Elixir

At the beginning of your end step, draw a card if your life total is greater than your starting life total. Otherwise, you gain 2 life.

Deathpact Angel

Flying
When Deathpact Angel dies, create a 1/1 white and black Cleric creature token. It has "{3}{W}{B}{B}, {T}, Sacrifice this creature: Return a card named Deathpact Angel from your graveyard to the battlefield."

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Venser's Journal

You have no maximum hand size.
At the beginning of your upkeep, you gain 1 life for each card in your hand.

Liesa, Shroud of Dusk

Rather than pay {2} for each previous time you've cast this spell from the command zone this game, pay 2 life that many times.
Flying, lifelink
Whenever a player casts a spell, they lose 2 life.

Fracture

Destroy target artifact, enchantment, or planeswalker.

Felidar Sovereign

Vigilance, lifelink
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Children of Korlis

Sacrifice Children of Korlis: You gain life equal to the life you've lost this turn. (Damage causes loss of life.)

Approach of the Second Sun

If this spell was cast from your hand and you've cast another spell named Approach of the Second Sun this game, you win the game. Otherwise, put Approach of the Second Sun into its owner's library seventh from the top and you gain 7 life.

Marshland Bloodcaster

Flying
{1}{B}, {T}: Rather than pay the mana cost of the next spell you cast this turn, you may pay life equal to that spell's mana value.

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature and you return up to one target creature card from your graveyard to your hand.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Martyr of Sands

{1}, Reveal X white cards from your hand, Sacrifice Martyr of Sands: You gain three times X life.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Brave the Sands

Creatures you control have vigilance.
Each creature you control can block an additional creature each combat.

Righteous Valkyrie

Flying
Whenever another Angel or Cleric enters the battlefield under your control, you gain life equal to that creature's toughness.
As long as you have at least 7 life more than your starting life total, creatures you control get +2/+2.

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, Serra Ascendant gets +5/+5 and has flying.

Rampage of the Valkyries

When Rampage of the Valkyries enters the battlefield, create a 4/4 white Angel creature token with flying and vigilance.
Whenever an Angel you control dies, each other player sacrifices a creature.

Sangromancer

Flying
Whenever a creature an opponent controls dies, you may gain 3 life.
Whenever an opponent discards a card, you may gain 3 life.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with Tree of Perdition's toughness.