Kjeldoran Dead

When Kjeldoran Dead enters, sacrifice a creature.
{B}: Regenerate Kjeldoran Dead.

Blood Seeker

Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Demon of Death's Gate

You may pay 6 life and sacrifice three black creatures rather than pay this spell's mana cost.
Flying, trample

Dogged Pursuit

At the beginning of your end step, each opponent loses 1 life and you gain 1 life.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Poisonbelly Ogre

Whenever another creature enters, its controller loses 1 life.

Nightshade Harvester

Whenever a land an opponent controls enters, that player loses 1 life. Put a +1/+1 counter on Nightshade Harvester.

Insectile Aberration

Delver of Secrets

At the beginning of your upkeep, look at the top card of your library. You may reveal that card. If an instant or sorcery card is revealed this way, transform Delver of Secrets.

Delver of Secrets // Insectile Aberration

Civic Saber

Equipped creature gets +1/+0 for each of its colors.
Equip {1}

Island

Hissing Miasma

Whenever a creature attacks you, its controller loses 1 life.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Loyal Subordinate

Menace (This creature can't be blocked except by two or more creatures.)
Lieutenant — At the beginning of combat on your turn, if you control your commander, each opponent loses 3 life.

Memnite

Morsel Theft

Prowl {1}{B} (You may cast this for its prowl cost if you dealt combat damage to a player this turn with a Rogue.)
Target player loses 3 life and you gain 3 life. If this spell's prowl cost was paid, draw a card.

Epicure of Blood

Whenever you gain life, each opponent loses 1 life.

Glaring Spotlight

Creatures your opponents control with hexproof can be the targets of spells and abilities you control as though they didn't have hexproof.
{3}, Sacrifice Glaring Spotlight: Creatures you control gain hexproof until end of turn and can't be blocked this turn.

Marchesa's Decree

When Marchesa's Decree enters, you become the monarch.
Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life.

Sygg, River Cutthroat

At the beginning of each end step, if an opponent lost 3 or more life this turn, you may draw a card. (Damage causes loss of life.)

Molting Snakeskin

Enchant creature
Enchanted creature gets +2/+0 and has "{2}{B}: Regenerate this creature."

Dread Rider

{1}{B}, {T}, Exile a creature card from your graveyard: Target opponent loses 3 life.

Baneful Omen

At the beginning of your end step, you may reveal the top card of your library. If you do, each opponent loses life equal to that card's mana value.

Netherborn Phalanx

When Netherborn Phalanx enters, each opponent loses 1 life for each creature they control.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then then shuffle. Transmute only as a sorcery.)

Killing Wave

For each creature, its controller sacrifices it unless they pay X life.

Swamp

Pongify

Destroy target creature. It can't be regenerated. Its controller creates a 3/3 green Ape creature token.

Feast on the Fallen

At the beginning of each upkeep, if an opponent lost life last turn, put a +1/+1 counter on target creature you control.

Mana Chains

Enchant creature
Enchanted creature has "Cumulative upkeep {1}." (At the beginning of its controller's upkeep, that player puts an age counter on it, then sacrifices it unless they pay its upkeep cost for each age counter on it.)

Curse of Disturbance

Enchant player
Whenever enchanted player is attacked, create a 2/2 black Zombie creature token. Each opponent attacking that player does the same.

Chalice of Death

Chalice of Life

{T}: You gain 1 life. Then if you have at least 10 life more than your starting life total, transform Chalice of Life.

Chalice of Life // Chalice of Death

Malakir Mire

Malakir Mire enters tapped.
{T}: Add {B}.

Malakir Rebirth

Choose target creature. You lose 2 life. Until end of turn, that creature gains "When this creature dies, return it to the battlefield tapped under its owner's control."

Malakir Rebirth // Malakir Mire

Chainer's Torment

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I, II — Chainer's Torment deals 2 damage to each opponent and you gain 2 life.
III — Create an X/X black Nightmare Horror creature token, where X is half your life total, rounded up. It deals X damage to you.

Duskmantle Guildmage

{1}{U}{B}: Whenever a card is put into an opponent's graveyard from anywhere this turn, that player loses 1 life.
{2}{U}{B}: Target player mills two cards.

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Manifold Key

{1}, {T}: Untap another target artifact.
{3}, {T}: Target creature can't be blocked this turn.

Access Tunnel

{T}: Add {C}.
{3}, {T}: Target creature with power 3 or less can't be blocked this turn.

Laquatus's Champion

When Laquatus's Champion enters, target player loses 6 life.
When Laquatus's Champion leaves the battlefield, that player gains 6 life.
{B}: Regenerate Laquatus's Champion.

Contaminated Bond

Enchant creature (Target a creature as you cast this. This card enters attached to that creature.)
Whenever enchanted creature attacks or blocks, its controller loses 3 life.

Paradise Mantle

Equipped creature has "{T}: Add one mana of any color."
Equip {1}

Retreat to Hagra

Landfall — Whenever a land you control enters, choose one —
• Target creature gets +1/+0 and gains deathtouch until end of turn.
• Each opponent loses 1 life and you gain 1 life.

Changeling Outcast

Changeling (This card is every creature type.)
Changeling Outcast can't block and can't be blocked.

Cruel Reality

Enchant player
At the beginning of enchanted player's upkeep, that player sacrifices a creature or planeswalker of their choice. If the player can't, they lose 5 life.

Opposition Agent

Flash
You control your opponents while they're searching their libraries.
While an opponent is searching their library, they exile each card they find. You may play those cards for as long as they remain exiled, and you may spend mana as though it were mana of any color to cast them.

Curse of Fool's Wisdom

Enchant player
Whenever enchanted player draws a card, they lose 2 life and you gain 2 life.
Madness {3}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Ceremonious Rejection

Phthisis

Destroy target creature. Its controller loses life equal to its power plus its toughness.
Suspend 5—{1}{B} (Rather than cast this card from your hand, you may pay {1}{B} and exile it with five time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)

Demonic Appetite

Enchant creature you control
Enchanted creature gets +3/+3.
At the beginning of your upkeep, sacrifice a creature.

Leechridden Swamp

({T}: Add {B}.)
Leechridden Swamp enters tapped.
{B}, {T}: Each opponent loses 1 life. Activate only if you control two or more black permanents.

Perilous Predicament

Each opponent sacrifices an artifact creature and a nonartifact creature of their choice.

Archfiend of Spite

Flying
Whenever a source an opponent controls deals damage to Archfiend of Spite, that source's controller loses that much life unless they sacrifice that many permanents of their choice.
Madness {3}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Mage Hunter

Whenever an opponent casts or copies an instant or sorcery spell, they lose 1 life.

Jace's Archivist

{U}, {T}: Each player discards their hand, then draws cards equal to the greatest number of cards a player discarded this way.

Calculating Lich

Menace
Whenever a creature attacks one of your opponents, that player loses 1 life.

Shadow Slice

Target opponent loses 3 life.
Cipher (Then you may exile this spell card encoded on a creature you control. Whenever that creature deals combat damage to a player, its controller may cast a copy of the encoded card without paying its mana cost.)

Kheru Bloodsucker

Whenever a creature you control with toughness 4 or greater dies, each opponent loses 2 life and you gain 2 life.
{2}{B}, Sacrifice another creature: Put a +1/+1 counter on Kheru Bloodsucker.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Mardu Shadowspear

Whenever Mardu Shadowspear attacks, each opponent loses 1 life.
Dash {1}{B} (You may cast this spell for its dash cost. If you do, it gains haste, and it's returned from the battlefield to its owner's hand at the beginning of the next end step.)

Blood Reckoning

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life.

Invisible Stalker

Hexproof (This creature can't be the target of spells or abilities your opponents control.)
Invisible Stalker can't be blocked.

Indulgent Tormentor

Flying
At the beginning of your upkeep, draw a card unless target opponent sacrifices a creature of their choice or pays 3 life.

Profane Transfusion

Two target players exchange life totals. You create an X/X colorless Horror artifact creature token, where X is the difference between those players' life totals.

Alms of the Vein

Target opponent loses 3 life and you gain 3 life.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

True-Name Nemesis

As True-Name Nemesis enters, choose a player.
True-Name Nemesis has protection from the chosen player.

Marauding Blight-Priest

Detection Tower

{T}: Add {C}.
{1}, {T}: Until end of turn, your opponents and creatures your opponents control with hexproof can be the targets of spells and abilities you control as though they didn't have hexproof.

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Isolation Cell

Whenever an opponent casts a creature spell, that player loses 2 life unless they pay {2}.

Blood Clock

At the beginning of each player's upkeep, that player returns a permanent they control to its owner's hand unless they pay 2 life.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Keen Duelist

At the beginning of your upkeep, you and target opponent each reveal the top card of your library. You each lose life equal to the mana value of the card revealed by the other player. You each put the card you revealed into your hand.

Breathstealer's Crypt

If a player would draw a card, instead they draw a card and reveal it. If it's a creature card, that player discards it unless they pay 3 life.

Dash Hopes

When you cast this spell, any player may pay 5 life. If a player does, counter Dash Hopes.
Counter target spell.

Caged Zombie

{1}{B}, {T}: Each opponent loses 2 life. Activate only if a creature died this turn.

Undermine

Counter target spell. Its controller loses 3 life.

Piranha Marsh

Piranha Marsh enters tapped.
When Piranha Marsh enters, target player loses 1 life.
{T}: Add {B}.

Death Pits of Rath

Whenever a creature is dealt damage, destroy it. It can't be regenerated.

Massacre Wurm

When this creature enters, creatures your opponents control get -2/-2 until end of turn.
Whenever a creature an opponent controls dies, that player loses 2 life.

Innocent Blood

Each player sacrifices a creature of their choice.

Fate Unraveler

Whenever an opponent draws a card, Fate Unraveler deals 1 damage to that player.

Maggot Carrier

When Maggot Carrier enters, each player loses 1 life.

Dread Presence

Whenever a Swamp you control enters, choose one —
• You draw a card and you lose 1 life.
• Dread Presence deals 2 damage to any target and you gain 2 life.

Night Market Lookout

Whenever Night Market Lookout becomes tapped, each opponent loses 1 life and you gain 1 life.

Prying Blade

Equipped creature gets +1/+0.
Whenever equipped creature deals combat damage to a player, create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Stinkdrinker Bandit

Prowl {1}{B} (You may cast this for its prowl cost if you dealt combat damage to a player this turn with a Goblin or Rogue.)
Whenever a Rogue you control attacks and isn't blocked, it gets +2/+1 until end of turn.

Bontu the Glorified

Menace, indestructible
Bontu the Glorified can't attack or block unless a creature died under your control this turn.
{1}{B}, Sacrifice another creature: Scry 1. Each opponent loses 1 life and you gain 1 life.

Blessing of Belzenlok

Target creature gets +2/+1 until end of turn. If it's legendary, it also gains lifelink until end of turn.