Tainted Remedy

If an opponent would gain life, that player loses that much life instead.

Spectator Seating

Spectator Seating enters tapped unless you have two or more opponents.
{T}: Add {R} or {W}.

Devour Flesh

Target player sacrifices a creature of their choice, then gains life equal to that creature's toughness.

Energy Bolt

Choose one —
• Energy Bolt deals X damage to target player or planeswalker.
• Target player gains X life.

Illumination

Counter target artifact or enchantment spell. Its controller gains life equal to its mana value.

Wall of Shards

Defender, flying
Cumulative upkeep—An opponent gains 1 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Negate

Mana Drain

Counter target spell. At the beginning of your next main phase, add an amount of {C} equal to that spell's mana value.

Exquisite Archangel

Flying
If you would lose the game, instead exile Exquisite Archangel and your life total becomes equal to your starting life total.

Wild Ricochet

You may choose new targets for target instant or sorcery spell. Then copy that spell. You may choose new targets for the copy.

Reverberate

Copy target instant or sorcery spell. You may choose new targets for the copy.

Chromatic Lantern

Lands you control have "{T}: Add one mana of any color."
{T}: Add one mana of any color.

Idyllic Tutor

Search your library for an enchantment card, reveal it, put it into your hand, then shuffle.

Protective Sphere

{1}, Pay 1 life: Prevent all damage that would be dealt to you this turn by a source of your choice that shares a color with the mana spent on this activation cost. (Colorless mana prevents no damage.)

Scourge of the Skyclaves

Kicker {4}{B}
When you cast this spell, if it was kicked, each player loses half their life, rounded up.
Scourge of the Skyclaves's power and toughness are each equal to 20 minus the highest life total among players.

Ghostly Prison

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Arid Mesa

{T}, Pay 1 life, Sacrifice Arid Mesa: Search your library for a Mountain or Plains card, put it onto the battlefield, then shuffle.

Cyclonic Rift

Return target nonland permanent you don't control to its owner's hand.
Overload {6}{U} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Chromatic Orrery

You may spend mana as though it were mana of any color.
{T}: Add {C}{C}{C}{C}{C}.
{5}, {T}: Draw a card for each color among permanents you control.

Scrubland

City of Brass

Whenever City of Brass becomes tapped, it deals 1 damage to you.
{T}: Add one mana of any color.

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Congregate

Target player gains 2 life for each creature on the battlefield.

Reflecting Pool

{T}: Add one mana of any type that a land you control could produce.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Lich's Mirror

If you would lose the game, instead shuffle your hand, your graveyard, and all permanents you own into your library, then draw seven cards and your life total becomes 20.

Torgaar, Famine Incarnate

As an additional cost to cast this spell, you may sacrifice any number of creatures. This spell costs {2} less to cast for each creature sacrificed this way.
When Torgaar, Famine Incarnate enters, up to one target player's life total becomes half their starting life total, rounded down.

Sorin Markov

+2: Sorin Markov deals 2 damage to any target and you gain 2 life.
−3: Target opponent's life total becomes 10.
−7: You control target player during that player's next turn.

Sol Ring

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

False Cure

Until end of turn, whenever a player gains life, that player loses 2 life for each 1 life they gained.

Bloodchief Ascension

At the beginning of each end step, if an opponent lost 2 or more life this turn, you may put a quest counter on Bloodchief Ascension. (Damage causes loss of life.)
Whenever a card is put into an opponent's graveyard from anywhere, if Bloodchief Ascension has three or more quest counters on it, you may have that player lose 2 life. If you do, you gain 2 life.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Rhystic Study

Whenever an opponent casts a spell, you may draw a card unless that player pays {1}.

Heliod's Intervention

Choose one —
• Destroy X target artifacts and/or enchantments.
• Target player gains twice X life.

Mystical Tutor

Search your library for an instant or sorcery card, reveal it, then shuffle and put that card on top.

Bloodstained Mire

{T}, Pay 1 life, Sacrifice Bloodstained Mire: Search your library for a Swamp or Mountain card, put it onto the battlefield, then shuffle.

Maze of Ith

{T}: Untap target attacking creature. Prevent all combat damage that would be dealt to and dealt by that creature this turn.

Hallowed Fountain

({T}: Add {W} or {U}.)
As Hallowed Fountain enters, you may pay 2 life. If you don't, it enters tapped.

Revenge

Double your life total. Target opponent loses half their life, rounded up.

Revival

Return target creature card with mana value 3 or less from your graveyard to the battlefield.

Revival // Revenge

Polluted Delta

{T}, Pay 1 life, Sacrifice Polluted Delta: Search your library for an Island or Swamp card, put it onto the battlefield, then shuffle.

Cryptborn Horror

Trample
Cryptborn Horror enters with X +1/+1 counters on it, where X is the total life lost by your opponents this turn.

Rakdos Signet

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Grim Tutor

Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.

Xantcha, Sleeper Agent

Xantcha, Sleeper Agent enters under the control of an opponent of your choice.
Xantcha attacks each combat if able and can't attack its owner or planeswalkers its owner controls.
{3}: Xantcha's controller loses 2 life and you draw a card. Any player may activate this ability.

Temporal Extortion

When you cast this spell, any player may pay half their life, rounded up. If a player does, counter Temporal Extortion.
Take an extra turn after this one.

Vault of Champions

Vault of Champions enters tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Zirda, the Dawnwaker

Companion — Each permanent card in your starting deck has an activated ability. (If this card is your chosen companion, you may put it into your hand from outside the game for {3} as a sorcery.)
Abilities you activate that aren't mana abilities cost {2} less to activate. This effect can't reduce the mana in that cost to less than one mana.
{1}, {T}: Target creature can't block this turn.

Condemn

Put target attacking creature on the bottom of its owner's library. Its controller gains life equal to its toughness.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Ali from Cairo

Damage that would reduce your life total to less than 1 reduces it to 1 instead.

Cruel Tutor

Seek

Search target opponent's library for a card and exile it. You gain life equal to its mana value. Then that player shuffles.

Hide

Put target artifact or enchantment on the bottom of its owner's library.

Hide // Seek

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Angel's Grace

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
You can't lose the game this turn and your opponents can't win the game this turn. Until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Valkmira, Protector's Shield

If a source an opponent controls would deal damage to you or a permanent you control, prevent 1 of that damage.
Whenever you or another permanent you control becomes the target of a spell or ability an opponent controls, counter that spell or ability unless its controller pays {1}.

Reidane, God of the Worthy

Flying, vigilance
Snow lands your opponents control enter tapped.
Noncreature spells your opponents cast with mana value 4 or greater cost {2} more to cast.

Reidane, God of the Worthy // Valkmira, Protector's Shield

Dimir Signet

Stunning Reversal

The next time you would lose the game this turn, instead draw seven cards and your life total becomes 1.
Exile Stunning Reversal.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Flooded Strand

{T}, Pay 1 life, Sacrifice Flooded Strand: Search your library for a Plains or Island card, put it onto the battlefield, then shuffle.

God-Pharaoh's Statue

Spells your opponents cast cost {2} more to cast.
At the beginning of your end step, each opponent loses 1 life.

Luxury Suite

Luxury Suite enters tapped unless you have two or more opponents.
{T}: Add {B} or {R}.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Plateau

Tundra

Magister Sphinx

Flying
When Magister Sphinx enters, target player's life total becomes 10.

Angel of Grace

Flash
Flying
When Angel of Grace enters, until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.
{4}{W}{W}, Exile Angel of Grace from your graveyard: Your life total becomes 10.

Children of Korlis

Sacrifice Children of Korlis: You gain life equal to the life you've lost this turn. (Damage causes loss of life.)

Marsh Flats

{T}, Pay 1 life, Sacrifice Marsh Flats: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Temple of Enlightenment

This land enters tapped.
When this land enters, scry 1. (Look at the top card of your library. You may put that card on the bottom.)
{T}: Add {W} or {U}.

Sacred Foundry

({T}: Add {R} or {W}.)
As Sacred Foundry enters, you may pay 2 life. If you don't, it enters tapped.

Enlightened Tutor

Search your library for an artifact or enchantment card, reveal it, then shuffle and put that card on top.

Arbiter of Knollridge

Vigilance
When Arbiter of Knollridge enters, each player's life total becomes the highest life total among all players.

Mathas, Fiend Seeker

Menace
At the beginning of your end step, put a bounty counter on target creature an opponent controls. For as long as that creature has a bounty counter on it, it has "When this creature dies, each opponent draws a card and gains 2 life."

Blood Crypt

({T}: Add {B} or {R}.)
As Blood Crypt enters, you may pay 2 life. If you don't, it enters tapped.

Forbidden Orchard

{T}: Add one mana of any color.
Whenever you tap Forbidden Orchard for mana, target opponent creates a 1/1 colorless Spirit creature token.

Rain of Gore

If a spell or ability would cause its controller to gain life, that player loses that much life instead.

Archfiend of Despair

Flying
Your opponents can't gain life.
At the beginning of each end step, each opponent loses life equal to the life that player lost this turn. (Damage causes loss of life.)

Leyline of Anticipation

If Leyline of Anticipation is in your opening hand, you may begin the game with it on the battlefield.
You may cast spells as though they had flash.

Heartless Hidetsugu

{T}: Heartless Hidetsugu deals damage to each player equal to half that player's life total, rounded down.

Aria of Flame

When Aria of Flame enters, each opponent gains 10 life.
Whenever you cast an instant or sorcery spell, put a verse counter on Aria of Flame, then it deals damage equal to the number of verse counters on it to target player or planeswalker.

Reverse the Sands

Redistribute any number of players' life totals. (Each of those players gets one life total back.)

Arcane Signet

Tainted Sigil

{T}, Sacrifice Tainted Sigil: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Malignus

Malignus's power and toughness are each equal to half the highest life total among your opponents, rounded up.
Damage that would be dealt by Malignus can't be prevented.

Drain Power

Target player activates a mana ability of each land they control. Then that player loses all unspent mana and you add the mana lost this way.

Erebos, God of the Dead

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
Your opponents can't gain life.
{1}{B}, Pay 2 life: Draw a card.

Fortune Thief

Damage that would reduce your life total to less than 1 reduces it to 1 instead.
Morph {R}{R} (You may cast this card face down as a 2/2 creature for {3}. Turn it face up any time for its morph cost.)

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Mana Confluence

{T}, Pay 1 life: Add one mana of any color.

Kor Haven

{T}: Add {C}.
{1}{W}, {T}: Prevent all combat damage that would be dealt by target attacking creature this turn.

Underground Sea

Counterspell

Raugrin Triome

({T}: Add {U}, {R}, or {W}.)
Raugrin Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Twilight Prophet

Flying
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your upkeep, if you have the city's blessing, reveal the top card of your library and put it into your hand. Each opponent loses X life and you gain X life, where X is that card's mana value.