One Thousand Lashes

Enchant creature
Enchanted creature can't attack or block, and its activated abilities can't be activated.
At the beginning of the upkeep of enchanted creature's controller, that player loses 1 life.

Forsaken Wastes

Players can't gain life.
At the beginning of each player's upkeep, that player loses 1 life.
Whenever this enchantment becomes the target of a spell, that spell's controller loses 5 life.

Incendiary

Enchant creature
At the beginning of your upkeep, you may put a fuse counter on this Aura.
When enchanted creature dies, this Aura deals X damage to any target, where X is the number of fuse counters on this Aura.

Unnatural Hunger

Enchant creature
At the beginning of the upkeep of enchanted creature's controller, this Aura deals damage equal to that creature's power to that player unless they sacrifice another creature of their choice.

Withercrown

Enchant creature
Enchanted creature has base power 0 and has "At the beginning of your upkeep, you lose 1 life unless you sacrifice this creature."

Aurora of Emrakul

Flying, deathtouch
Whenever this creature attacks, each opponent loses 3 life.

Cryptolith Fragment

This artifact enters tapped.
{T}: Add one mana of any color. Each player loses 1 life.
At the beginning of your upkeep, if each player has 10 or less life, transform this artifact.

Cryptolith Fragment // Aurora of Emrakul

Duskmantle Seer

Flying
At the beginning of your upkeep, each player reveals the top card of their library, loses life equal to that card's mana value, then puts it into their hand.

Creeping Dread

At the beginning of your upkeep, each player discards a card. Each opponent who discarded a card that shares a card type with the card you discarded loses 3 life. (Players reveal the discarded cards simultaneously.)

Persistent Constrictor

At the beginning of each opponent's upkeep, they lose 1 life and you put a -1/-1 counter on up to one target creature they control.
Persist (When this creature dies, if it had no -1/-1 counters on it, return it to the battlefield under its owner's control with a -1/-1 counter on it.)

Clawing Torment

Enchant artifact or creature
As long as enchanted permanent is a creature, it gets -1/-1 and can't block.
Enchanted permanent has "At the beginning of your upkeep, you lose 1 life."

Numbing Dose

Enchant artifact or creature
Enchanted permanent doesn't untap during its controller's untap step.
At the beginning of the upkeep of enchanted permanent's controller, that player loses 1 life.

Curse of the Pierced Heart

Enchant player
At the beginning of enchanted player's upkeep, this Aura deals 1 damage to that player or a planeswalker that player controls.

Gibbering Descent

At the beginning of each player's upkeep, that player loses 1 life and discards a card.
Hellbent — Skip your upkeep step if you have no cards in hand.
Madness {2}{B}{B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Relic Bane

Enchant artifact
Enchanted artifact has "At the beginning of your upkeep, you lose 2 life."

Seizan, Perverter of Truth

At the beginning of each player's upkeep, that player loses 2 life and draws two cards.

Warp Artifact

Enchant artifact
At the beginning of the upkeep of enchanted artifact's controller, this Aura deals 1 damage to that player.

Mind Whip

Enchant creature
At the beginning of the upkeep of enchanted creature's controller, that player may pay {3}. If they don't, this Aura deals 2 damage to that player and you tap that creature.

Shrieking Affliction

At the beginning of each opponent's upkeep, if that player has one or fewer cards in hand, they lose 3 life.

Hollowborn Barghest

At the beginning of your upkeep, if you have no cards in hand, each opponent loses 2 life.
At the beginning of each opponent's upkeep, if that player has no cards in hand, they lose 2 life.

Cursed Land

Enchant land
At the beginning of the upkeep of enchanted land's controller, this Aura deals 1 damage to that player.

Grievous Wound

Enchant player
Enchanted player can't gain life.
Whenever enchanted player is dealt damage, they lose half their life, rounded up.

Leeching Lurker

Lifelink
Nightbound (If a player casts at least two spells during their own turn, it becomes day next turn.)

Curse of Leeches

Enchant player
As this permanent transforms into Curse of Leeches, attach it to a player.
At the beginning of enchanted player's upkeep, they lose 1 life and you gain 1 life.
Daybound (If a player casts no spells during their own turn, it becomes night next turn.)

Curse of Leeches // Leeching Lurker

Titan Hunter

At the beginning of each player's end step, if no creatures died this turn, this creature deals 4 damage to that player.
{1}{B}, Sacrifice a creature: You gain 4 life.

Errant Minion

Enchant creature
At the beginning of the upkeep of enchanted creature's controller, that player may pay any amount of mana. This Aura deals 2 damage to that player. Prevent X of that damage, where X is the amount of mana that player paid this way.

Power Taint

Enchant enchantment
At the beginning of the upkeep of enchanted enchantment's controller, that player loses 2 life unless they pay {2}.
Cycling {2} ({2}, Discard this card: Draw a card.)

Etherwrought Page

At the beginning of your upkeep, choose one —
• You gain 2 life.
• Surveil 1. (Look at the top card of your library. You may put that card into your graveyard.)
• Each opponent loses 1 life.

Archfiend of Despair

Flying
Your opponents can't gain life.
At the beginning of each end step, each opponent loses life equal to the life that player lost this turn. (Damage causes loss of life.)

Parasitic Bond

Enchant creature
At the beginning of the upkeep of enchanted creature's controller, this Aura deals 2 damage to that player.

Feedback

Enchant enchantment
At the beginning of the upkeep of enchanted enchantment's controller, this Aura deals 1 damage to that player.

Cruel Reality

Enchant player
At the beginning of enchanted player's upkeep, that player sacrifices a creature or planeswalker of their choice. If the player can't, they lose 5 life.

Torment of Scarabs

Enchant player
At the beginning of enchanted player's upkeep, that player loses 3 life unless they sacrifice a nonland permanent of their choice or discard a card.

Festering Wound

Enchant creature
At the beginning of your upkeep, you may put an infection counter on this Aura.
At the beginning of the upkeep of enchanted creature's controller, this Aura deals X damage to that player, where X is the number of infection counters on this Aura.

Power Leak

Enchant enchantment
At the beginning of the upkeep of enchanted enchantment's controller, that player may pay any amount of mana. This Aura deals 2 damage to that player. Prevent X of that damage, where X is the amount of mana that player paid this way.

Curse Artifact

Enchant artifact
At the beginning of the upkeep of enchanted artifact's controller, this Aura deals 2 damage to that player unless they sacrifice that artifact.

Blood Tyrant

Flying, trample
At the beginning of your upkeep, each player loses 1 life. Put a +1/+1 counter on this creature for each 1 life lost this way.
Whenever a player loses the game, put five +1/+1 counters on this creature.

Deadpool, Trading Card

As Deadpool enters, you may exchange his text box and another creature's.
At the beginning of your upkeep, you lose 3 life.
{3}, Sacrifice this creature: Each other player draws a card.

Soul Bleed

Enchant creature
At the beginning of the upkeep of enchanted creature's controller, that player loses 1 life.

Pillory of the Sleepless

Enchant creature
Enchanted creature can't attack or block.
Enchanted creature has "At the beginning of your upkeep, you lose 1 life."

Drana's Emissary

Flying
At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Stab Wound

Enchant creature
Enchanted creature gets -2/-2.
At the beginning of the upkeep of enchanted creature's controller, that player loses 2 life.

Lingering Death

Enchant creature
At the beginning of the end step of enchanted creature's controller, that player sacrifices that creature.

Smoldering Tar

At the beginning of your upkeep, target player loses 1 life.
Sacrifice this enchantment: It deals 4 damage to target creature. Activate only as a sorcery.

Pillar Tombs of Aku

At the beginning of each player's upkeep, that player may sacrifice a creature of their choice. If that player doesn't, they lose 5 life and you sacrifice this enchantment.

Doom Foretold

At the beginning of each player's upkeep, that player sacrifices a nonland, nontoken permanent of their choice. If that player can't, they discard a card, they lose 2 life, you draw a card, you gain 2 life, you create a 2/2 white Knight creature token with vigilance, then you sacrifice this enchantment.

Infectious Curse

Enchant player
Spells you cast that target enchanted player cost {1} less to cast.
At the beginning of enchanted player's upkeep, that player loses 1 life and you gain 1 life.

Accursed Witch

Spells your opponents cast that target this creature cost {1} less to cast.
When this creature dies, return it to the battlefield transformed under your control attached to target opponent.

Accursed Witch // Infectious Curse

Takklemaggot

Enchant creature
At the beginning of the upkeep of enchanted creature's controller, put a -0/-1 counter on that creature.
When enchanted creature dies, that creature's controller chooses a creature that this card could enchant. If the player does, return this card to the battlefield under your control attached to that creature. If they don't, return this card to the battlefield under your control as a non-Aura enchantment. It loses "enchant creature" and gains "At the beginning of that player's upkeep, this enchantment deals 1 damage to that player."

Dark Suspicions

At the beginning of each opponent's upkeep, that player loses X life, where X is the number of cards in that player's hand minus the number of cards in your hand.

Havoc Festival

Players can't gain life.
At the beginning of each player's upkeep, that player loses half their life, rounded up.

Leeching Licid

{B}, {T}: This creature loses this ability and becomes an Aura enchantment with enchant creature. Attach it to target creature. You may pay {B} to end this effect.
At the beginning of the upkeep of enchanted creature's controller, this creature deals 1 damage to that player.

Strangling Grasp

Enchant creature or planeswalker an opponent controls
At the beginning of your upkeep, enchanted permanent's controller sacrifices a nonland permanent of their choice, then that player loses 1 life.

Vengeful Strangler

This creature can't block.
When this creature dies, return it to the battlefield transformed under your control attached to target creature or planeswalker an opponent controls.

Vengeful Strangler // Strangling Grasp

Curse of Thirst

Enchant player
At the beginning of enchanted player's upkeep, this Aura deals damage to that player equal to the number of Curses attached to them.

Court of Ambition

When this enchantment enters, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.