Cosmos Elixir

At the beginning of your end step, draw a card if your life total is greater than your starting life total. Otherwise, you gain 2 life.

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, Serra Ascendant gets +5/+5 and has flying.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Mountain

Crested Sunmare

Other Horses you control have indestructible.
At the beginning of each end step, if you gained life this turn, create a 5/5 white Horse creature token.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Enlightened Tutor

Search your library for an artifact or enchantment card, reveal it, then shuffle and put that card on top.

Boseiju, Who Shelters All

Boseiju, Who Shelters All enters tapped.
{T}, Pay 2 life: Add {C}. If that mana is spent on an instant or sorcery spell, that spell can't be countered.

Rogue's Passage

{T}: Add {C}.
{4}, {T}: Target creature can't be blocked this turn.

Utter End

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature and you return up to one target creature card from your graveyard to your hand.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Crackling Doom

Crackling Doom deals 2 damage to each opponent. Each opponent sacrifices a creature with the greatest power among creatures that player controls.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Indulging Patrician

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your end step, if you gained 3 or more life this turn, each opponent loses 3 life.

Sunhome, Fortress of the Legion

{T}: Add {C}.
{2}{R}{W}, {T}: Target creature gains double strike until end of turn.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Darksteel Mutation

Enchant creature
Enchanted creature is an Insect artifact creature with base power and toughness 0/1 and has indestructible, and it loses all other abilities, card types, and creature types.

Licia, Sanguine Tribune

This spell costs {1} less to cast for each 1 life you gained this turn.
First strike, lifelink
Pay 5 life: Put three +1/+1 counters on Licia, Sanguine Tribune. Activate only during your turn and only once each turn.

Plains

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters, you may pay 2 life. If you don't, it enters tapped.

Isolated Chapel

Isolated Chapel enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Solemn Simulacrum

When Solemn Simulacrum enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When Solemn Simulacrum dies, you may draw a card.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Rakdos Signet

Mother of Runes

{T}: Target creature you control gains protection from the color of your choice until end of turn.

Path of Ancestry

Path of Ancestry enters tapped.
{T}: Add one mana of any color in your commander's color identity. When that mana is spent to cast a creature spell that shares a creature type with your commander, scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Spectator Seating

Spectator Seating enters tapped unless you have two or more opponents.
{T}: Add {R} or {W}.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Orzhov Signet

Luxury Suite

Luxury Suite enters tapped unless you have two or more opponents.
{T}: Add {B} or {R}.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Marsh Flats

{T}, Pay 1 life, Sacrifice Marsh Flats: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Trailblazer's Boots

Equipped creature has nonbasic landwalk. (It can't be blocked as long as defending player controls a nonbasic land.)
Equip {2}

Savai Triome

({T}: Add {R}, {W}, or {B}.)
Savai Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Smoldering Marsh

({T}: Add {B} or {R}.)
Smoldering Marsh enters tapped unless you control two or more basic lands.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Sacred Foundry

({T}: Add {R} or {W}.)
As Sacred Foundry enters, you may pay 2 life. If you don't, it enters tapped.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Light of Promise

Enchant creature
Enchanted creature has "Whenever you gain life, put that many +1/+1 counters on this creature."

Sol Ring

Bloodstained Mire

{T}, Pay 1 life, Sacrifice Bloodstained Mire: Search your library for a Swamp or Mountain card, put it onto the battlefield, then shuffle.

Canyon Slough

({T}: Add {B} or {R}.)
Canyon Slough enters tapped.
Cycling {2} ({2}, Discard this card: Draw a card.)

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Silent Clearing

{T}, Pay 1 life: Add {W} or {B}.
{1}, {T}, Sacrifice Silent Clearing: Draw a card.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Sword of the Animist

Equipped creature gets +1/+1.
Whenever equipped creature attacks, you may search your library for a basic land card, put it onto the battlefield tapped, then shuffle.
Equip {2}

Haunted Cloak

Equipped creature has vigilance, trample, and haste.
Equip {1} ({1}: Attach to target creature you control. Equip only as a sorcery.)

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik, Son of Yawgmoth.

Boros Signet

Deflecting Palm

The next time a source of your choice would deal damage to you this turn, prevent that damage. If damage is prevented this way, Deflecting Palm deals that much damage to that source's controller.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Black Market

Whenever a creature dies, put a charge counter on Black Market.
At the beginning of your first main phase, add {B} for each charge counter on Black Market.

Rune-Tail's Essence

Prevent all damage that would be dealt to creatures you control.

Rune-Tail, Kitsune Ascendant

When you have 30 or more life, flip Rune-Tail, Kitsune Ascendant.

Rune-Tail, Kitsune Ascendant // Rune-Tail's Essence

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Weathered Wayfarer

{W}, {T}: Search your library for a land card, reveal it, put it into your hand, then shuffle. Activate only if an opponent controls more lands than you.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Darksteel Plate

Indestructible
Equipped creature has indestructible.
Equip {2}

Chandra's Ignition

Target creature you control deals damage equal to its power to each other creature and each opponent.

Shizo, Death's Storehouse

{T}: Add {B}.
{B}, {T}: Target legendary creature gains fear until end of turn. (It can't be blocked except by artifact creatures and/or black creatures.)

Favor of the Mighty

Each creature with the highest mana value has protection from each color.

Clifftop Retreat

Clifftop Retreat enters tapped unless you control a Mountain or a Plains.
{T}: Add {R} or {W}.

Tymna the Weaver

Lifelink
At the beginning of each of your postcombat main phases, you may pay X life, where X is the number of opponents that were dealt combat damage this turn. If you do, draw X cards.
Partner (You can have two commanders if both have partner.)

Venser's Journal

You have no maximum hand size.
At the beginning of your upkeep, you gain 1 life for each card in your hand.

Mana Confluence

{T}, Pay 1 life: Add one mana of any color.

Mana Tithe

Counter target spell unless its controller pays {1}.

Kediss, Emberclaw Familiar

Whenever a commander you control deals combat damage to an opponent, it deals that much damage to each other opponent.
Partner (You can have two commanders if both have partner.)

Swamp

Spirit Link

Enchant creature (Target a creature as you cast this. This card enters attached to that creature.)
Whenever enchanted creature deals damage, you gain that much life.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Blessed Sanctuary

Prevent all noncombat damage that would be dealt to you and creatures you control.
Whenever a nontoken creature you control enters, create a 2/2 white Unicorn creature token.

Hammer of Nazahn

Whenever Hammer of Nazahn or another Equipment you control enters, you may attach that Equipment to target creature you control.
Equipped creature gets +2/+0 and has indestructible.
Equip {4}

Vault of Champions

Vault of Champions enters tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Revenge

Double your life total. Target opponent loses half their life, rounded up.

Revival

Return target creature card with mana value 3 or less from your graveyard to the battlefield.

Revival // Revenge

Ghen, Arcanum Weaver

{R}{W}{B}, {T}, Sacrifice an enchantment: Return target enchantment card from your graveyard to the battlefield.

Illicit Auction

Each player may bid life for control of target creature. You start the bidding with a bid of 0. In turn order, each player may top the high bid. The bidding ends if the high bid stands. The high bidder loses life equal to the high bid and gains control of the creature. (This effect lasts indefinitely.)

Command the Dreadhorde

Choose any number of target creature and/or planeswalker cards in graveyards. Command the Dreadhorde deals damage to you equal to the total mana value of those cards. Put them onto the battlefield under your control.

Burnished Hart

{3}, Sacrifice Burnished Hart: Search your library for up to two basic land cards, put them onto the battlefield tapped, then shuffle.

Stunning Reversal

The next time you would lose the game this turn, instead draw seven cards and your life total becomes 1.
Exile Stunning Reversal.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent or discards a card.

Vampiric Link

Enchant creature
Whenever enchanted creature deals damage, you gain that much life.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Divinity of Pride

Flying, lifelink
Divinity of Pride gets +4/+4 as long as you have 25 or more life.

Cradle of Vitality

Whenever you gain life, you may pay {1}{W}. If you do, put a +1/+1 counter on target creature for each 1 life you gained.