Acid Rain

Damnation

Destroy all creatures. They can't be regenerated.

Deathbringer Regent

Flying
When Deathbringer Regent enters, if you cast it from your hand and there are five or more other creatures on the battlefield, destroy all other creatures.

Sulfur Falls

Sulfur Falls enters tapped unless you control an Island or a Mountain.
{T}: Add {U} or {R}.

Sunpetal Grove

Sunpetal Grove enters tapped unless you control a Forest or a Plains.
{T}: Add {G} or {W}.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Nevinyrral's Disk

Nevinyrral's Disk enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Necromantic Selection

Destroy all creatures, then return a creature card put into a graveyard this way to the battlefield under your control. It's a black Zombie in addition to its other colors and types. Exile Necromantic Selection.

Anarchy

Azorius Signet

Doomskar

Destroy all creatures.
Foretell {1}{W}{W} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Paraselene

Destroy all enchantments. You gain 1 life for each enchantment destroyed this way.

Rakdos Signet

Cleansing Nova

Choose one —
• Destroy all creatures.
• Destroy all artifacts and enchantments.

Magus of the Disk

Magus of the Disk enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Bearer of the Heavens

When Bearer of the Heavens dies, destroy all permanents at the beginning of the next end step.

Back to Nature

Scrubland

Obliterate

This spell can't be countered.
Destroy all artifacts, creatures, and lands. They can't be regenerated.

Boompile

{T}: Flip a coin. If you win the flip, destroy all nonland permanents.

Supreme Verdict

This spell can't be countered.
Destroy all creatures.

Dragonskull Summit

Dragonskull Summit enters tapped unless you control a Swamp or a Mountain.
{T}: Add {B} or {R}.

Underground Sea

Tundra

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Raugrin Triome

({T}: Add {U}, {R}, or {W}.)
Raugrin Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Spectator Seating

Spectator Seating enters tapped unless you have two or more opponents.
{T}: Add {R} or {W}.

Akroma's Vengeance

Destroy all artifacts, creatures, and enchantments.
Cycling {3} ({3}, Discard this card: Draw a card.)

Dimir Signet

Boil

Ketria Triome

({T}: Add {G}, {U}, or {R}.)
Ketria Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Bountiful Promenade

Bountiful Promenade enters tapped unless you have two or more opponents.
{T}: Add {G} or {W}.

Savai Triome

({T}: Add {R}, {W}, or {B}.)
Savai Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Bust

Boom

Destroy target land you control and target land you don't control.

Boom // Bust

Rootbound Crag

Rootbound Crag enters tapped unless you control a Mountain or a Forest.
{T}: Add {R} or {G}.

Decree of Pain

Destroy all creatures. They can't be regenerated. Draw a card for each creature destroyed this way.
Cycling {3}{B}{B} ({3}{B}{B}, Discard this card: Draw a card.)
When you cycle Decree of Pain, all creatures get -2/-2 until end of turn.

Fight to the Death

Destroy all blocking creatures and all blocked creatures.

End Hostilities

Destroy all creatures and all permanents attached to creatures.

Planar Outburst

Destroy all nonland creatures.
Awaken 4—{5}{W}{W}{W} (If you cast this spell for {5}{W}{W}{W}, also put four +1/+1 counters on target land you control and it becomes a 0/0 Elemental creature with haste. It's still a land.)

Selesnya Signet

Izzet Signet

Blood on the Snow

Choose one —
• Destroy all creatures.
• Destroy all planeswalkers.
Then return a creature or planeswalker card with mana value X or less from your graveyard to the battlefield, where X is the amount of {S} spent to cast this spell. ({S} is mana from a snow source.)

Taiga

Bayou

Jodah, Archmage Eternal

Flying
You may pay {W}{U}{B}{R}{G} rather than pay the mana cost for spells you cast.

Whirlwind

Badlands

Bane of Progress

When Bane of Progress enters, destroy all artifacts and enchantments. Put a +1/+1 counter on Bane of Progress for each permanent destroyed this way.

Dawn

Aftermath (Cast this spell only from your graveyard. Then exile it.)
Return all creature cards with power 2 or less from your graveyard to your hand.

Dusk

Destroy all creatures with power 3 or greater.

Dusk // Dawn

Dread Cacodemon

When Dread Cacodemon enters, if you cast it from your hand, destroy all creatures your opponents control, then tap all other creatures you control.

Phyrexian Rebirth

Destroy all creatures, then create an X/X colorless Phyrexian Horror artifact creature token, where X is the number of creatures destroyed this way.

Glacial Fortress

Glacial Fortress enters tapped unless you control a Plains or an Island.
{T}: Add {W} or {U}.

Plateau

Nature's Ruin

Woodland Cemetery

Woodland Cemetery enters tapped unless you control a Swamp or a Forest.
{T}: Add {B} or {G}.

Bend or Break

Each player separates all nontoken lands they control into two piles. For each player, one of their piles is chosen by one of their opponents of their choice. Destroy all lands in the chosen piles. Tap all lands in the other piles.

Spire Garden

Spire Garden enters tapped unless you have two or more opponents.
{T}: Add {R} or {G}.

Command Tower

Catastrophe

Destroy all lands or all creatures. Creatures destroyed this way can't be regenerated.

Desolation Angel

Kicker {W}{W} (You may pay an additional {W}{W} as you cast this spell.)
Flying
When Desolation Angel enters, destroy all lands you control. If it was kicked, destroy all lands instead.

Tropical Island

Orzhov Signet

In Garruk's Wake

Destroy all creatures you don't control and all planeswalkers you don't control.

Calming Verse

Destroy all enchantments you don't control. Then if you control an untapped land, destroy all enchantments you control.

Bontu's Last Reckoning

Destroy all creatures. Lands you control don't untap during your next untap step.

Wakening Sun's Avatar

When Wakening Sun's Avatar enters, if you cast it from your hand, destroy all non-Dinosaur creatures.

Desolation Giant

Kicker {W}{W} (You may pay an additional {W}{W} as you cast this spell.)
When Desolation Giant enters, destroy all other creatures you control. If it was kicked, destroy all other creatures instead.

Clifftop Retreat

Clifftop Retreat enters tapped unless you control a Mountain or a Plains.
{T}: Add {R} or {W}.

Cleansing Meditation

Destroy all enchantments.
Threshold — If seven or more cards are in your graveyard, instead destroy all enchantments, then return all cards in your graveyard destroyed this way to the battlefield.

Vault of Champions

Vault of Champions enters tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Boros Signet

Myojin of Infinite Rage

Myojin of Infinite Rage enters with a divinity counter on it if you cast it from your hand.
Myojin of Infinite Rage has indestructible as long as it has a divinity counter on it.
Remove a divinity counter from Myojin of Infinite Rage: Destroy all lands.

Zagoth Triome

({T}: Add {B}, {G}, or {U}.)
Zagoth Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Decree of Annihilation

Exile all artifacts, creatures, and lands from the battlefield, all cards from all graveyards, and all cards from all hands.
Cycling {5}{R}{R} ({5}{R}{R}, Discard this card: Draw a card.)
When you cycle Decree of Annihilation, destroy all lands.

Golgari Signet

Kaya's Wrath

Destroy all creatures. You gain life equal to the number of creatures you controlled that were destroyed this way.

Indatha Triome

({T}: Add {W}, {B}, or {G}.)
Indatha Triome enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Jokulhaups

Destroy all artifacts, creatures, and lands. They can't be regenerated.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Myojin of Cleansing Fire

Myojin of Cleansing Fire enters with a divinity counter on it if you cast it from your hand.
Myojin of Cleansing Fire has indestructible as long as it has a divinity counter on it.
Remove a divinity counter from Myojin of Cleansing Fire: Destroy all other creatures.

Gruul Signet

Isolated Chapel

Isolated Chapel enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Hinterland Harbor

Hinterland Harbor enters tapped unless you control a Forest or an Island.
{T}: Add {G} or {U}.

Fall of the Thran

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Destroy all lands.
II, III — Each player returns two land cards from their graveyard to the battlefield.

Savannah

Devastation

Crucible of Worlds

Day of Judgment

Inspiring Vantage

Inspiring Vantage enters tapped unless you control two or fewer other lands.
{T}: Add {R} or {W}.

Hour of Revelation

This spell costs {3} less to cast if there are ten or more nonland permanents on the battlefield.
Destroy all nonland permanents.

Drowned Catacomb

Drowned Catacomb enters tapped unless you control an Island or a Swamp.
{T}: Add {U} or {B}.

Flashfires

Training Center

Training Center enters tapped unless you have two or more opponents.
{T}: Add {U} or {R}.

Simic Signet

Armageddon

Creeping Corrosion

Virtue's Ruin

Luxury Suite

Luxury Suite enters tapped unless you have two or more opponents.
{T}: Add {B} or {R}.

Crux of Fate

Choose one —
• Destroy all Dragon creatures.
• Destroy all non-Dragon creatures.

Multani's Decree

Destroy all enchantments. You gain 2 life for each enchantment destroyed this way.