Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Sire of Insanity

At the beginning of each end step, each player discards their hand.

Rain of Gore

If a spell or ability would cause its controller to gain life, that player loses that much life instead.

Words of Waste

{1}: The next time you would draw a card this turn, each opponent discards a card instead.

Curse of the Forsaken

Enchant player
Whenever a creature attacks enchanted player, its controller gains 1 life.

Curse of the Bloody Tome

Enchant player
At the beginning of enchanted player's upkeep, that player mills two cards.

Infectious Curse

Enchant player
Spells you cast that target enchanted player cost {1} less to cast.
At the beginning of enchanted player's upkeep, that player loses 1 life and you gain 1 life.

Accursed Witch

Spells your opponents cast that target Accursed Witch cost {1} less to cast.
When Accursed Witch dies, return it to the battlefield transformed under your control attached to target opponent.

Accursed Witch // Infectious Curse

Liliana's Caress

Whenever an opponent discards a card, that player loses 2 life.

Curse of Vengeance

Enchant player
Whenever enchanted player casts a spell, put a spite counter on Curse of Vengeance.
When enchanted player loses the game, you gain X life and draw X cards, where X is the number of spite counters on Curse of Vengeance.

Curse of Shallow Graves

Enchant player
Whenever a player attacks enchanted player with one or more creatures, that attacking player may create a tapped 2/2 black Zombie creature token.

Tymna the Weaver

Lifelink
At the beginning of each of your postcombat main phases, you may pay X life, where X is the number of opponents that were dealt combat damage this turn. If you do, draw X cards.
Partner (You can have two commanders if both have partner.)

Ludevic, Necro-Alchemist

At the beginning of each player's end step, that player may draw a card if a player other than you lost life this turn.
Partner (You can have two commanders if both have partner.)

Curse of Bloodletting

Enchant player
If a source would deal damage to enchanted player, it deals double that damage to that player instead.

Library of Leng

You have no maximum hand size.
If an effect causes you to discard a card, discard it, but you may put it on top of your library instead of into your graveyard.

Curse of Thirst

Enchant player
At the beginning of enchanted player's upkeep, Curse of Thirst deals damage to that player equal to the number of Curses attached to them.

Curse of Vitality

Enchant player
Whenever enchanted player is attacked, you gain 2 life. Each opponent attacking that player does the same.

Curse of Opulence

Enchant player
Whenever enchanted player is attacked, create a Gold token. Each opponent attacking that player does the same. (A Gold token is an artifact with "Sacrifice this artifact: Add one mana of any color.")

Cursed Land

Enchant land
At the beginning of the upkeep of enchanted land's controller, Cursed Land deals 1 damage to that player.

Curse of Echoes

Enchant player
Whenever enchanted player casts an instant or sorcery spell, each other player may copy that spell and may choose new targets for the copy they control.

Geth's Grimoire

Whenever an opponent discards a card, you may draw a card.

Magus of the Wheel

{1}{R}, {T}, Sacrifice Magus of the Wheel: Each player discards their hand, then draws seven cards.

Trespasser's Curse

Enchant player
Whenever a creature enchanted player controls enters, that player loses 1 life and you gain 1 life.

Curse of Inertia

Enchant player
Whenever a player attacks enchanted player with one or more creatures, that attacking player may tap or untap target permanent of their choice.

Captive Audience

Captive Audience enters under the control of an opponent of your choice.
At the beginning of your upkeep, choose one that hasn't been chosen —
• Your life total becomes 4.
• Discard your hand.
• Each opponent creates five 2/2 black Zombie creature tokens.

Curse of Disturbance

Enchant player
Whenever enchanted player is attacked, create a 2/2 black Zombie creature token. Each opponent attacking that player does the same.

Mortal Combat

At the beginning of your upkeep, if twenty or more creature cards are in your graveyard, you win the game.

Bottomless Pit

At the beginning of each player's upkeep, that player discards a card at random.

Curse of Chaos

Enchant player
Whenever a player attacks enchanted player with one or more creatures, that attacking player may discard a card. If the player does, they draw a card.

Citadel of Pain

At the beginning of each player's end step, Citadel of Pain deals X damage to that player, where X is the number of untapped lands they control.

Curse of Wizardry

As Curse of Wizardry enters, choose a color.
Whenever a player casts a spell of the chosen color, that player loses 1 life.

Last One Standing

Choose a creature at random, then destroy the rest.

Curse of the Nightly Hunt

Enchant player
Creatures enchanted player controls attack each combat if able.

Curse of Misfortunes

Enchant player
At the beginning of your upkeep, you may search your library for a Curse card that doesn't have the same name as a Curse attached to enchanted player, put it onto the battlefield attached to that player, then shuffle.

Solemn Simulacrum

When Solemn Simulacrum enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When Solemn Simulacrum dies, you may draw a card.

Curse of Verbosity

Enchant player
Whenever enchanted player is attacked, you draw a card. Each opponent attacking that player does the same.