Read the Bones

Scry 2, then draw two cards. You lose 2 life.

Triskaidekaphobia

At the beginning of your upkeep, choose one —
• Each player with exactly 13 life loses the game, then each player gains 1 life.
• Each player with exactly 13 life loses the game, then each player loses 1 life.

Greed

Pestilence

At the beginning of the end step, if no creatures are on the battlefield, sacrifice Pestilence.
{B}: Pestilence deals 1 damage to each creature and each player.

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters, you may pay 2 life. If you don't, it enters tapped.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Promise of Power

Choose one —
• You draw five cards and you lose 5 life.
• Create an X/X black Demon creature token with flying, where X is the number of cards in your hand.
Entwine {4} (Choose both if you pay the entwine cost.)

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Necrologia

Cast this spell only during your end step.
As an additional cost to cast this spell, pay X life.
Draw X cards.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with Tree of Perdition's toughness.

Underworld Connections

Enchant land
Enchanted land has "{T}, Pay 1 life: Draw a card."

Orzhov Signet

Children of Korlis

Sacrifice Children of Korlis: You gain life equal to the life you've lost this turn. (Damage causes loss of life.)

Angel's Grace

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
You can't lose the game this turn and your opponents can't win the game this turn. Until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.

Sol Ring

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Erebos, God of the Dead

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
Your opponents can't gain life.
{1}{B}, Pay 2 life: Draw a card.

Increasing Ambition

Search your library for a card and put that card into your hand. If this spell was cast from a graveyard, instead search your library for two cards and put those cards into your hand. Then shuffle.
Flashback {7}{B} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Vindicate

Blind Obedience

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Artifacts and creatures your opponents control enter tapped.

Hex Parasite

{X}{B/P}: Remove up to X counters from target permanent. For each counter removed this way, Hex Parasite gets +1/+0 until end of turn. ({B/P} can be paid with either {B} or 2 life.)

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Orzhov Basilica

Orzhov Basilica enters tapped.
When Orzhov Basilica enters, return a land you control to its owner's hand.
{T}: Add {W}{B}.

Swamp

Night's Whisper

Magus of the Mirror

{T}, Sacrifice Magus of the Mirror: Exchange life totals with target opponent. Activate only during your upkeep.

Isolated Chapel

Isolated Chapel enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Phyrexian Unlife

You don't lose the game for having 0 or less life.
As long as you have 0 or less life, all damage is dealt to you as though its source had infect. (Damage is dealt to you in the form of poison counters.)

Gilded Lotus

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Tainted Sigil

{T}, Sacrifice Tainted Sigil: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Vona, Butcher of Magan

Vigilance, lifelink
{T}, Pay 7 life: Destroy target nonland permanent. Activate only during your turn.

Austere Command

Choose two —
• Destroy all artifacts.
• Destroy all enchantments.
• Destroy all creatures with mana value 3 or less.
• Destroy all creatures with mana value 4 or greater.

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Mortify

Utter End

Snuff Out

If you control a Swamp, you may pay 4 life rather than pay this spell's mana cost.
Destroy target nonblack creature. It can't be regenerated.

Solemnity

Players can't get counters.
Counters can't be put on artifacts, creatures, enchantments, or lands.

Reverse the Sands

Redistribute any number of players' life totals. (Each of those players gets one life total back.)

Vedalken Orrery

You may cast spells as though they had flash.

Temple of Silence

Temple of Silence enters tapped.
When Temple of Silence enters, scry 1.
{T}: Add {W} or {B}.

Sign in Blood

Target player draws two cards and loses 2 life.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Ancient Craving

You draw three cards and you lose 3 life.

Hatred

As an additional cost to cast this spell, pay X life.
Target creature gets +X/+0 until end of turn.

Exquisite Archangel

Flying
If you would lose the game, instead exile Exquisite Archangel and your life total becomes equal to your starting life total.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Caves of Koilos

{T}: Add {C}.
{T}: Add {W} or {B}. Caves of Koilos deals 1 damage to you.

Tainted Field

{T}: Add {C}.
{T}: Add {W} or {B}. Activate only if you control a Swamp.

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: Wall of Blood gets +1/+1 until end of turn.

Oketra's Last Mercy

Your life total becomes equal to your starting life total. Lands you control don't untap during your next untap step.

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Solemn Simulacrum

When Solemn Simulacrum enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When Solemn Simulacrum dies, you may draw a card.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Burnished Hart

{3}, Sacrifice Burnished Hart: Search your library for up to two basic land cards, put them onto the battlefield tapped, then shuffle.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Anguished Unmaking

Exile target nonland permanent. You lose 3 life.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Plains

Platinum Angel

Flying
You can't lose the game and your opponents can't win the game.

Myriad Landscape

Myriad Landscape enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Merciless Eviction

Choose one —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all planeswalkers.

Phyrexian Processor

As Phyrexian Processor enters, pay any amount of life.
{4}, {T}: Create an X/X black Phyrexian Minion creature token, where X is the life paid as Phyrexian Processor entered.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Ancient Tomb

{T}: Add {C}{C}. Ancient Tomb deals 2 damage to you.

Near-Death Experience

At the beginning of your upkeep, if you have exactly 1 life, you win the game.

Evra, Halcyon Witness

Lifelink
{4}: Exchange your life total with Evra, Halcyon Witness's power.

Grand Abolisher

During your turn, your opponents can't cast spells or activate abilities of artifacts, creatures, or enchantments.

Kambal, Consul of Allocation

Whenever an opponent casts a noncreature spell, that player loses 2 life and you gain 2 life.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Hall of the Bandit Lord

Hall of the Bandit Lord enters tapped.
{T}, Pay 3 life: Add {C}. If that mana is spent on a creature spell, it gains haste.

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Ambition's Cost

Selenia, Dark Angel

Flying
Pay 2 life: Return Selenia, Dark Angel to its owner's hand.

Temple of Aclazotz

(Transforms from Arguel's Blood Fast.)
{T}: Add {B}.
{T}, Sacrifice a creature: You gain life equal to the sacrificed creature's toughness.

Arguel's Blood Fast

{1}{B}, Pay 2 life: Draw a card.
At the beginning of your upkeep, if you have 5 or less life, you may transform Arguel's Blood Fast.

Arguel's Blood Fast // Temple of Aclazotz

Boseiju, Who Shelters All

Boseiju, Who Shelters All enters tapped.
{T}, Pay 2 life: Add {C}. If that mana is spent on an instant or sorcery spell, that spell can't be countered.

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Phyrexian Reclamation

{1}{B}, Pay 2 life: Return target creature card from your graveyard to your hand.

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.