Tainted Remedy

If an opponent would gain life, that player loses that much life instead.

Thermo-Alchemist

Defender
{T}: Thermo-Alchemist deals 1 damage to each opponent.
Whenever you cast an instant or sorcery spell, untap Thermo-Alchemist.

Horizon Stone

If you would lose unspent mana, that mana becomes colorless instead.

Seizan, Perverter of Truth

At the beginning of each player's upkeep, that player loses 2 life and draws two cards.

Firebrand Archer

Whenever you cast a noncreature spell, this creature deals 1 damage to each opponent.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with Tree of Perdition's toughness.

Acidic Soil

Acidic Soil deals damage to each player equal to the number of lands they control.

Sword of the Paruns

As long as equipped creature is tapped, tapped creatures you control get +2/+0.
As long as equipped creature is untapped, untapped creatures you control get +0/+2.
{3}: You may tap or untap equipped creature.
Equip {3}

Havoc Festival

Players can't gain life.
At the beginning of each player's upkeep, that player loses half their life, rounded up.

Kaervek the Merciless

Whenever an opponent casts a spell, Kaervek the Merciless deals damage equal to that spell's mana value to any target.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Mogis, God of Slaughter

Indestructible
As long as your devotion to black and red is less than seven, Mogis isn't a creature.
At the beginning of each opponent's upkeep, Mogis deals 2 damage to that player unless they sacrifice a creature of their choice.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Electrodominance

Electrodominance deals X damage to any target. You may cast a spell with mana value X or less from your hand without paying its mana cost.

Netherborn Phalanx

When Netherborn Phalanx enters, each opponent loses 1 life for each creature they control.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then then shuffle. Transmute only as a sorcery.)

Angrath's Marauders

If a source you control would deal damage to a permanent or player, it deals double that damage to that permanent or player instead.

Inferno

Inferno deals 6 damage to each creature and each player.

Manabarbs

Whenever a player taps a land for mana, Manabarbs deals 1 damage to that player.

Snow-Covered Mountain

Smallpox

Each player loses 1 life, discards a card, sacrifices a creature of their choice, then sacrifices a land of their choice.

Spiteful Visions

At the beginning of each player's draw step, that player draws an additional card.
Whenever a player draws a card, Spiteful Visions deals 1 damage to that player.

Each player loses a third of their life, then discards a third of the cards in their hand, then sacrifices a third of the creatures they control of their choice, then sacrifices a third of the lands they control of their choice. Round up each time.

Skull Rend

Skull Rend deals 2 damage to each opponent. Those players each discard two cards at random.

Tyrant's Choice

Will of the council — Starting with you, each player votes for death or torture. If death gets more votes, each opponent sacrifices a creature of their choice. If torture gets more votes or the vote is tied, each opponent loses 4 life.

Furnace of Rath

If a source would deal damage to a permanent or player, it deals double that damage to that permanent or player instead.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Tectonic Giant

Whenever Tectonic Giant attacks or becomes the target of a spell an opponent controls, choose one —
• Tectonic Giant deals 3 damage to each opponent.
• Exile the top two cards of your library. Choose one of them. Until the end of your next turn, you may play that card.

Archfiend of Despair

Flying
Your opponents can't gain life.
At the beginning of each end step, each opponent loses life equal to the life that player lost this turn. (Damage causes loss of life.)

Lightning Reaver

Haste; fear (This creature can't be blocked except by artifact creatures and/or black creatures.)
Whenever Lightning Reaver deals combat damage to a player, put a charge counter on it.
At the beginning of your end step, Lightning Reaver deals damage equal to the number of charge counters on it to each opponent.

Temple of the False God

{T}: Add {C}{C}. Activate only if you control five or more lands.

Guttersnipe

Whenever you cast an instant or sorcery spell, this creature deals 2 damage to each opponent.

Stormfist Crusader

Menace
At the beginning of your upkeep, each player draws a card and loses 1 life.

Rolling Earthquake

Rolling Earthquake deals X damage to each creature without horsemanship and each player.

Fiery Emancipation

If a source you control would deal damage to a permanent or player, it deals triple that damage to that permanent or player instead.

Forsaken Wastes

Players can't gain life.
At the beginning of each player's upkeep, that player loses 1 life.
Whenever Forsaken Wastes becomes the target of a spell, that spell's controller loses 5 life.

Molten Disaster

Kicker {R} (You may pay an additional {R} as you cast this spell.)
If this spell was kicked, it has split second. (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
Molten Disaster deals X damage to each creature without flying and each player.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Umbral Mantle

Equipped creature has "{3}, {Q}: This creature gets +2/+2 until end of turn." ({Q} is the untap symbol.)
Equip {0}

War's Toll

Whenever an opponent taps a land for mana, tap all lands that player controls.
If a creature an opponent controls attacks, all creatures that opponent controls attack if able.

Plague Spitter

At the beginning of your upkeep, Plague Spitter deals 1 damage to each creature and each player.
When Plague Spitter dies, it deals 1 damage to each creature and each player.

Subversion

At the beginning of your upkeep, each opponent loses 1 life. You gain life equal to the life lost this way.

Snow-Covered Forest

Twilight Prophet

Flying
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your upkeep, if you have the city's blessing, reveal the top card of your library and put it into your hand. Each opponent loses X life and you gain X life, where X is that card's mana value.

Zo-Zu the Punisher

Whenever a land enters, Zo-Zu the Punisher deals 2 damage to that land's controller.

Dictate of the Twin Gods

Flash
If a source would deal damage to a permanent or player, it deals double that damage to that permanent or player instead.

Spellshock

Whenever a player casts a spell, Spellshock deals 2 damage to that player.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Yurlok of Scorch Thrash

Vigilance
A player losing unspent mana causes that player to lose that much life.
{1}, {T}: Each player adds {B}{R}{G}.

Palace Siege

As Palace Siege enters, choose Khans or Dragons.
• Khans — At the beginning of your upkeep, return target creature card from your graveyard to your hand.
• Dragons — At the beginning of your upkeep, each opponent loses 2 life and you gain 2 life.

Leyline Tyrant

Flying
You don't lose unspent red mana as steps and phases end.
When Leyline Tyrant dies, you may pay any amount of {R}. When you do, it deals that much damage to any target.

Heartless Hidetsugu

{T}: Heartless Hidetsugu deals damage to each player equal to half that player's life total, rounded down.

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Snow-Covered Swamp

Slagstorm

Choose one —
• Slagstorm deals 3 damage to each creature.
• Slagstorm deals 3 damage to each player.

Baneful Omen

At the beginning of your end step, you may reveal the top card of your library. If you do, each opponent loses life equal to that card's mana value.

Earthquake

Earthquake deals X damage to each creature without flying and each player.

Leyline of Abundance

If Leyline of Abundance is in your opening hand, you may begin the game with it on the battlefield.
Whenever you tap a creature for mana, add an additional {G}.
{6}{G}{G}: Put a +1/+1 counter on each creature you control.

Ankh of Mishra

Whenever a land enters, Ankh of Mishra deals 2 damage to that land's controller.

Animate Dead

Enchant creature card in a graveyard
When Animate Dead enters, if it's on the battlefield, it loses "enchant creature card in a graveyard" and gains "enchant creature put onto the battlefield with Animate Dead." Return enchanted creature card to the battlefield under your control and attach Animate Dead to it. When Animate Dead leaves the battlefield, that creature's controller sacrifices it.
Enchanted creature gets -1/-0.

Fate Unraveler

Whenever an opponent draws a card, Fate Unraveler deals 1 damage to that player.

Savage Lands

Savage Lands enters tapped.
{T}: Add {B}, {R}, or {G}.

Rain of Gore

If a spell or ability would cause its controller to gain life, that player loses that much life instead.

Barbed Wire

At the beginning of each player's upkeep, Barbed Wire deals 1 damage to that player.
{2}: Prevent the next 1 damage that would be dealt by Barbed Wire this turn.

Loyal Subordinate

Menace (This creature can't be blocked except by two or more creatures.)
Lieutenant — At the beginning of combat on your turn, if you control your commander, each opponent loses 3 life.

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Spear Spewer

Defender
{T}: Spear Spewer deals 1 damage to each player.

Citadel of Pain

At the beginning of each player's end step, Citadel of Pain deals X damage to that player, where X is the number of untapped lands they control.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

God-Pharaoh's Statue

Spells your opponents cast cost {2} more to cast.
At the beginning of your end step, each opponent loses 1 life.

Dire Fleet Ravager

Menace, deathtouch
When Dire Fleet Ravager enters, each player loses a third of their life, rounded up.

Sulfuric Vortex

At the beginning of each player's upkeep, Sulfuric Vortex deals 2 damage to that player.
If a player would gain life, that player gains no life instead.

Worldgorger Dragon

Flying, trample
When Worldgorger Dragon enters, exile all other permanents you control.
When Worldgorger Dragon leaves the battlefield, return the exiled cards to the battlefield under their owners' control.

Torment of Hailfire

Repeat the following process X times. Each opponent loses 3 life unless that player sacrifices a nonland permanent of their choice or discards a card.

Ill-Gotten Inheritance

At the beginning of your upkeep, Ill-Gotten Inheritance deals 1 damage to each opponent and you gain 1 life.
{5}{B}, Sacrifice Ill-Gotten Inheritance: It deals 4 damage to target opponent and you gain 4 life.

Spawn of Mayhem

Spectacle {1}{B}{B} (You may cast this spell for its spectacle cost rather than its mana cost if an opponent lost life this turn.)
Flying, trample
At the beginning of your upkeep, Spawn of Mayhem deals 1 damage to each player. Then if you have 10 or less life, put a +1/+1 counter on Spawn of Mayhem.