Negate

Thermo-Alchemist

Defender
{T}: This creature deals 1 damage to each opponent.
Whenever you cast an instant or sorcery spell, untap this creature.

The Lord of Pain

Menace
Your opponents can't gain life.
Whenever a player casts their first spell each turn, choose another target player. The Lord of Pain deals damage equal to that spell's mana value to the chosen player.

Tzaangor Shaman

Flying
Sorcerous Elixir — Whenever this creature deals combat damage to a player, copy the next instant or sorcery spell you cast this turn when you cast it. You may choose new targets for the copy.

Bojuka Bog

This land enters tapped.
When this land enters, exile target player's graveyard.
{T}: Add {B}.

Cyclonic Rift

Return target nonland permanent you don't control to its owner's hand.
Overload {6}{U} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Haunted Ridge

This land enters tapped unless you control two or more other lands.
{T}: Add {B} or {R}.

Shipwreck Marsh

This land enters tapped unless you control two or more other lands.
{T}: Add {U} or {B}.

Heartless Hidetsugu

{T}: Heartless Hidetsugu deals damage to each player equal to half that player's life total, rounded down.

Rakdos Signet

Talisman of Creativity

{T}: Add {C}.
{T}: Add {U} or {R}. This artifact deals 1 damage to you.

Lavaglide Pathway

Riverglide Pathway

Riverglide Pathway // Lavaglide Pathway

Chandra, Torch of Defiance

+1: Exile the top card of your library. You may cast that card. If you don't, Chandra deals 2 damage to each opponent.
+1: Add {R}{R}.
−3: Chandra deals 4 damage to target creature.
−7: You get an emblem with "Whenever you cast a spell, this emblem deals 5 damage to any target."

Dauthi Voidwalker

Shadow (This creature can block or be blocked by only creatures with shadow.)
If a card would be put into an opponent's graveyard from anywhere, instead exile it with a void counter on it.
{T}, Sacrifice this creature: Choose an exiled card an opponent owns with a void counter on it. You may play it this turn without paying its mana cost.

Past in Flames

Each instant and sorcery card in your graveyard gains flashback until end of turn. The flashback cost is equal to its mana cost.
Flashback {4}{R} (You may cast this card from your graveyard for its flashback cost. Then exile it.)

Spear Spewer

Defender
{T}: This creature deals 1 damage to each player.

Mutalith Vortex Beast

Trample
Warp Vortex — When this creature enters, flip a coin for each opponent you have. For each flip you win, draw a card. For each flip you lose, this creature deals 3 damage to that player.

The Lost and the Damned

Whenever a land you control enters from anywhere other than your hand or you cast a spell from anywhere other than your hand, create a 3/3 red Spawn creature token.

Lord of Change

Flying, ward {3}
Architect of Deception — When this creature enters, draw three cards.

Island

Shepherd of Rot

{T}: Each player loses 1 life for each Zombie on the battlefield.

Nalfeshnee

Flying
Whenever you cast a spell from exile, copy it. You may choose new targets for the copy. If it's a permanent spell, the copy gains haste and "At the beginning of the end step, sacrifice this permanent." (A copy of a permanent spell becomes a token.)

Jori En, Ruin Diver

Whenever you cast your second spell each turn, draw a card.

Talisman of Dominance

{T}: Add {C}.
{T}: Add {U} or {B}. This artifact deals 1 damage to you.

Morphic Pool

This land enters tapped unless you have two or more opponents.
{T}: Add {U} or {B}.

Poxwalkers

Deathtouch
Curse of the Walking Pox — Whenever you cast a spell from anywhere other than your hand, return this card from your graveyard to the battlefield tapped.

Keeper of Secrets

First strike, haste
Symphony of Pain — Whenever you cast a spell from anywhere other than your hand, this creature deals damage equal to that spell's mana value to target opponent.

Stormcarved Coast

This land enters tapped unless you control two or more other lands.
{T}: Add {U} or {R}.

Sol Ring

Painful Quandary

Whenever an opponent casts a spell, that player loses 5 life unless they discard a card.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Noise Marine

Cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)
Sonic Blaster — When this creature enters, it deals damage equal to the number of spells you've cast this turn to any target.

Nightscape Familiar

Blue spells and red spells you cast cost {1} less to cast.
{1}{B}: Regenerate this creature.

Heralds of Tzeentch

Flying
Cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)

Sulfurous Springs

{T}: Add {C}.
{T}: Add {B} or {R}. This land deals 1 damage to you.

Blasphemous Act

This spell costs {1} less to cast for each creature on the battlefield.
Blasphemous Act deals 13 damage to each creature.

Swamp

Chaos Terminator Lord

Lord of Chaos — At the beginning of combat on your turn, another target creature you control gains double strike until end of turn.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Wild-Magic Sorcerer

The first spell you cast from exile each turn has cascade. (When you cast your first spell from exile, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)

Vedalken Orrery

You may cast spells as though they had flash.

Delayed Blast Fireball

Delayed Blast Fireball deals 2 damage to each opponent and each creature they control. If this spell was cast from exile, it deals 5 damage to each opponent and each creature they control instead.
Foretell {4}{R}{R} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Chaos Warp

The owner of target permanent shuffles it into their library, then reveals the top card of their library. If it's a permanent card, they put it onto the battlefield.

Rhystic Study

Whenever an opponent casts a spell, you may draw a card unless that player pays {1}.

Stormfist Crusader

Menace
At the beginning of your upkeep, each player draws a card and loses 1 life.

Drowned Catacomb

This land enters tapped unless you control an Island or a Swamp.
{T}: Add {U} or {B}.

The Ruinous Powers

At the beginning of your upkeep, choose an opponent at random. Exile the top card of that player's library. Until end of turn, you may play that card and you may spend mana as though it were mana of any color to cast it. When you cast a spell this way, its owner loses life equal to its mana value.

Neheb, the Eternal

Afflict 3 (Whenever this creature becomes blocked, defending player loses 3 life.)
At the beginning of each of your postcombat main phases, add {R} for each 1 life your opponents have lost this turn.

Searstep Pathway

Blightstep Pathway

Blightstep Pathway // Searstep Pathway

Luxury Suite

This land enters tapped unless you have two or more opponents.
{T}: Add {B} or {R}.

An Offer You Can't Refuse

Counter target noncreature spell. Its controller creates two Treasure tokens. (They're artifacts with "{T}, Sacrifice this token: Add one mana of any color.")

Mountain

Murkwater Pathway

Clearwater Pathway

Clearwater Pathway // Murkwater Pathway

Xander's Lounge

({T}: Add {U}, {B}, or {R}.)
This land enters tapped.
Cycling {3} ({3}, Discard this card: Draw a card.)

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Dimir Signet

Dragonskull Summit

This land enters tapped unless you control a Swamp or a Mountain.
{T}: Add {B} or {R}.

Vial Smasher the Fierce

Whenever you cast your first spell each turn, choose an opponent at random. Vial Smasher deals damage equal to that spell's mana value to that player or a planeswalker that player controls.
Partner (You can have two commanders if both have partner.)

Swiftwater Cliffs

This land enters tapped.
When this land enters, you gain 1 life.
{T}: Add {U} or {R}.

Sloppity Bilepiper

Jolly Gutpipes — {2}, {T}, Sacrifice a creature: The next creature spell you cast this turn has cascade. (When you next cast a creature spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)

Profane Tutor

Suspend 2—{1}{B} (Rather than cast this card from your hand, pay {1}{B} and exile it with two time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Search your library for a card, put that card into your hand, then shuffle.

Underground River

{T}: Add {C}.
{T}: Add {U} or {B}. This land deals 1 damage to you.

Florian, Voldaren Scion

First strike
At the beginning of each of your postcombat main phases, look at the top X cards of your library, where X is the total amount of life your opponents lost this turn. Exile one of those cards and put the rest on the bottom of your library in a random order. You may play the exiled card this turn.

Plague Drone

Flying
Rot Fly — If an opponent would gain life, that player loses that much life instead.

Warstorm Surge

Whenever a creature you control enters, it deals damage equal to its power to any target.

Rakdos Charm

Choose one —
• Exile target player's graveyard.
• Destroy target artifact.
• Each creature deals 1 damage to its controller.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice this artifact: Draw a card.

Loyal Subordinate

Menace (This creature can't be blocked except by two or more creatures.)
Lieutenant — At the beginning of combat on your turn, if you control your commander, each opponent loses 3 life.

Ancestral Vision

Suspend 4—{U} (Rather than cast this card from your hand, pay {U} and exile it with four time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Target player draws three cards.

Crumbling Necropolis

This land enters tapped.
{T}: Add {U}, {B}, or {R}.

Training Center

This land enters tapped unless you have two or more opponents.
{T}: Add {U} or {R}.

Jeska's Will

Choose one. If you control a commander as you cast this spell, you may choose both instead.
• Add {R} for each card in target opponent's hand.
• Exile the top three cards of your library. You may play them this turn.

Command Tower

Dark Apostle

Gift of Chaos — {3}, {T}: The next noncreature spell you cast this turn has cascade. (When you cast that spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)

Inevitable Betrayal

Suspend 3—{1}{U}{U} (Rather than cast this card from your hand, pay {1}{U}{U} and exile it with three time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Search target opponent's library for a creature card and put that card onto the battlefield under your control. Then that player shuffles.

Mana Confluence

{T}, Pay 1 life: Add one mana of any color.

Mandate of Abaddon

Choose target creature you control. Destroy all creatures with power less than that creature's power.

Talisman of Indulgence

{T}: Add {C}.
{T}: Add {B} or {R}. This artifact deals 1 damage to you.

Fellwar Stone

Chaos Defiler

Trample
Battle Cannon — When this creature enters or dies, for each opponent, choose a nonland permanent that player controls. Destroy one of them chosen at random.

Terminate

Destroy target creature. It can't be regenerated.

Abaddon the Despoiler

Trample
Mark of Chaos Ascendant — During your turn, spells you cast from your hand with mana value X or less have cascade, where X is the total amount of life your opponents have lost this turn.

Prosper, Tome-Bound

Deathtouch
Mystic Arcanum — At the beginning of your end step, exile the top card of your library. Until the end of your next turn, you may play that card.
Pact Boon — Whenever you play a card from exile, create a Treasure token.

Court of Ambition

When this enchantment enters, you become the monarch.
At the beginning of your upkeep, each opponent loses 3 life unless they discard a card. If you're the monarch, instead each opponent loses 6 life unless they discard two cards.