End Hostilities

Destroy all creatures and all permanents attached to creatures.

Blightsteel Colossus

Trample, infect, indestructible
If Blightsteel Colossus would be put into a graveyard from anywhere, reveal Blightsteel Colossus and shuffle it into its owner's library instead.

Wrath of God

Destroy all creatures. They can't be regenerated.

Colossus of Akros

Defender, indestructible
{10}: Monstrosity 10. (If this creature isn't monstrous, put ten +1/+1 counters on it and it becomes monstrous.)
As long as Colossus of Akros is monstrous, it has trample and can attack as though it didn't have defender.

Rout

You may cast Rout as though it had flash if you pay {2} more to cast it. (You may cast it any time you could cast an instant.)
Destroy all creatures. They can't be regenerated.

Kefnet the Mindful

Flying, indestructible
Kefnet the Mindful can't attack or block unless you have seven or more cards in hand.
{3}{U}: Draw a card, then you may return a land you control to its owner's hand.

Phylactery Lich

Indestructible
As Phylactery Lich enters, put a phylactery counter on an artifact you control.
When you control no permanents with phylactery counters on them, sacrifice Phylactery Lich.

Scourglass

{T}, Sacrifice Scourglass: Destroy all permanents except for artifacts and lands. Activate only during your upkeep.

Selfless Spirit

Flying
Sacrifice Selfless Spirit: Creatures you control gain indestructible until end of turn.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Fell the Mighty

Destroy all creatures with power greater than target creature's power.

Catastrophe

Destroy all lands or all creatures. Creatures destroyed this way can't be regenerated.

Sen Triplets

At the beginning of your upkeep, choose target opponent. This turn, that player can't cast spells or activate abilities and plays with their hand revealed. You may play lands and cast spells from that player's hand this turn.

Darksteel Juggernaut

Indestructible
Darksteel Juggernaut's power and toughness are each equal to the number of artifacts you control.
Darksteel Juggernaut attacks each combat if able.

Day of Judgment

Shatter the Sky

Each player who controls a creature with power 4 or greater draws a card. Then destroy all creatures.

Nevinyrral's Disk

Nevinyrral's Disk enters tapped.
{1}, {T}: Destroy all artifacts, creatures, and enchantments.

Phyrexian Rebirth

Destroy all creatures, then create an X/X colorless Phyrexian Horror artifact creature token, where X is the number of creatures destroyed this way.

Sphinx of the Steel Wind

Flying, first strike, vigilance, lifelink, protection from red and from green

Planar Cleansing

Doomskar

Destroy all creatures.
Foretell {1}{W}{W} (During your turn, you may pay {2} and exile this card from your hand face down. Cast it on a later turn for its foretell cost.)

Akroma's Vengeance

Destroy all artifacts, creatures, and enchantments.
Cycling {3} ({3}, Discard this card: Draw a card.)

Darksteel Sentinel

Flash (You may cast this spell any time you could cast an instant.)
Vigilance
Indestructible (Damage and effects that say "destroy" don't destroy this creature. If its toughness is 0 or less, it's still put into its owner's graveyard.)

Darksteel Ingot

Indestructible (Effects that say "destroy" don't destroy this artifact.)
{T}: Add one mana of any color.

Darksteel Relic

Indestructible (Effects that say "destroy" don't destroy this artifact.)

Damnation

Darksteel Forge

Artifacts you control have indestructible. (Effects that say "destroy" don't destroy them. Artifact creatures with indestructible can't be destroyed by damage.)

Ondu Skyruins

Ondu Skyruins enters tapped.
{T}: Add {W}.

Ondu Inversion

Ondu Inversion // Ondu Skyruins

Soul of New Phyrexia

Trample
{5}: Permanents you control gain indestructible until end of turn.
{5}, Exile Soul of New Phyrexia from your graveyard: Permanents you control gain indestructible until end of turn.

Hour of Reckoning

Convoke (Your creatures can help cast this spell. Each creature you tap while casting this spell pays for {1} or one mana of that creature's color.)
Destroy all nontoken creatures.

Darksteel Gargoyle

Flying
Indestructible (Damage and effects that say "destroy" don't destroy this creature.)

Phenax, God of Deception

Indestructible
As long as your devotion to blue and black is less than seven, Phenax isn't a creature.
Creatures you control have "{T}: Target player mills X cards, where X is this creature's toughness."

Supreme Verdict

This spell can't be countered.
Destroy all creatures.

Crux of Fate

Choose one —
• Destroy all Dragon creatures.
• Destroy all non-Dragon creatures.

Sparkhunter Masticore

As an additional cost to cast this spell, discard a card.
Protection from planeswalkers
{1}: Sparkhunter Masticore deals 1 damage to target planeswalker.
{3}: Sparkhunter Masticore gains indestructible until end of turn.

Enigma Sphinx

Flying
When Enigma Sphinx is put into your graveyard from the battlefield, put it into your library third from the top.
Cascade (When you cast this spell, exile cards from the top of your library until you exile a nonland card that costs less. You may cast it without paying its mana cost. Put the exiled cards on the bottom in a random order.)

Darksteel Colossus

Trample, indestructible
If Darksteel Colossus would be put into a graveyard from anywhere, reveal Darksteel Colossus and shuffle it into its owner's library instead.

Boompile

{T}: Flip a coin. If you win the flip, destroy all nonland permanents.

Merieke Ri Berit

Merieke Ri Berit doesn't untap during your untap step.
{T}: Gain control of target creature for as long as you control Merieke Ri Berit. When Merieke Ri Berit leaves the battlefield or becomes untapped, destroy that creature. It can't be regenerated.

Sydri, Galvanic Genius

{U}: Target noncreature artifact becomes an artifact creature with power and toughness each equal to its mana value until end of turn.
{W}{B}: Target artifact creature gains deathtouch and lifelink until end of turn.

Dauntless Escort

Sacrifice Dauntless Escort: Creatures you control gain indestructible until end of turn.

Myojin of Cleansing Fire

Myojin of Cleansing Fire enters with a divinity counter on it if you cast it from your hand.
Myojin of Cleansing Fire has indestructible as long as it has a divinity counter on it.
Remove a divinity counter from Myojin of Cleansing Fire: Destroy all other creatures.

Cleansing Nova

Choose one —
• Destroy all creatures.
• Destroy all artifacts and enchantments.

Hour of Revelation

This spell costs {3} less to cast if there are ten or more nonland permanents on the battlefield.
Destroy all nonland permanents.

Child of Alara

Trample
When Child of Alara dies, destroy all nonland permanents. They can't be regenerated.

Fated Retribution

Destroy all creatures and planeswalkers. If it's your turn, scry 2.

Time Wipe

Return a creature you control to its owner's hand, then destroy all creatures.

Bontu's Last Reckoning

Destroy all creatures. Lands you control don't untap during your next untap step.

Kaya's Wrath

Destroy all creatures. You gain life equal to the number of creatures you controlled that were destroyed this way.