Mycosynth Wellspring

When Mycosynth Wellspring enters or is put into a graveyard from the battlefield, you may search your library for a basic land card, reveal it, put it into your hand, then shuffle.

Tattered Mummy

When Tattered Mummy dies, each opponent loses 2 life.

Solemn Simulacrum

When this creature enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When this creature dies, you may draw a card.

Blood Seeker

Whenever a creature an opponent controls enters, you may have that player lose 1 life.

Sinister Monolith

At the beginning of combat on your turn, each opponent loses 1 life and you gain 1 life.
{T}, Pay 2 life, Sacrifice Sinister Monolith: Draw two cards. Activate only as a sorcery.

Lampad of Death's Vigil

{1}, Sacrifice a creature: Each opponent loses 1 life and you gain 1 life.

Agent of the Iron Throne

Commander creatures you own have "Whenever an artifact or creature you control is put into a graveyard from the battlefield, each opponent loses 1 life."

Jinxed Idol

At the beginning of your upkeep, Jinxed Idol deals 2 damage to you.
Sacrifice a creature: Target opponent gains control of Jinxed Idol.

Epicure of Blood

Whenever you gain life, each opponent loses 1 life.

Serrated Scorpion

When Serrated Scorpion dies, it deals 2 damage to each opponent and you gain 2 life.

Prized Statue

When Prized Statue enters or is put into a graveyard from the battlefield, create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Cauldron Familiar

When Cauldron Familiar enters, each opponent loses 1 life and you gain 1 life.
Sacrifice a Food: Return Cauldron Familiar from your graveyard to the battlefield.

Vicious Conquistador

Whenever Vicious Conquistador attacks, each opponent loses 1 life.

Fear of Lost Teeth

When Fear of Lost Teeth dies, it deals 1 damage to any target and you gain 1 life.

Ayara, First of Locthwain

Whenever Ayara, First of Locthwain or another black creature you control enters, each opponent loses 1 life and you gain 1 life.
{T}, Sacrifice another black creature: Draw a card.

Patron of the Nezumi

Rat offering (You may cast this spell any time you could cast an instant by sacrificing a Rat and paying the difference in mana costs between this and the sacrificed Rat. Mana cost includes color.)
Whenever a permanent is put into an opponent's graveyard, that player loses 1 life.

Priest of Forgotten Gods

{T}, Sacrifice two other creatures: Any number of target players each lose 2 life and sacrifice a creature of their choice. You add {B}{B} and draw a card.

Thornbow Archer

Whenever Thornbow Archer attacks, each opponent who doesn't control an Elf loses 1 life.

Chupacabra Echo

Fathomless descent — When Chupacabra Echo enters, target creature an opponent controls gets -X/-X until end of turn, where X is the number of permanent cards in your graveyard.

Vampire Spawn

When this creature enters, each opponent loses 2 life and you gain 2 life.

Enduring Tenacity

Whenever you gain life, target opponent loses that much life.
When Enduring Tenacity dies, if it was a creature, return it to the battlefield under its owner's control. It's an enchantment. (It's not a creature.)

Sivriss, Nightmare Speaker

{T}, Sacrifice another creature or an artifact: For each opponent, you mill a card, then return that card from your graveyard to your hand unless that player pays 3 life. (To mill a card, put the top card of your library into your graveyard.)
Choose a Background (You can have a Background as a second commander.)

Vraan, Executioner Thane

Whenever one or more other creatures you control die, each opponent loses 2 life and you gain 2 life. This ability triggers only once each turn.

Sleeper Agent

When Sleeper Agent enters, target opponent gains control of it.
At the beginning of your upkeep, Sleeper Agent deals 2 damage to you.

Drossclaw

Living weapon (When this Equipment enters, create a 0/0 black Phyrexian Germ creature token, then attach this to it.)
Equipped creature gets +1/+1.
Whenever equipped creature attacks, each opponent loses 1 life.
Equip {2}

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Pulse Tracker

Whenever this creature attacks, each opponent loses 1 life.

Etched Familiar

When Etched Familiar dies, each opponent loses 2 life and you gain 2 life.

Tyrant's Choice

Will of the council — Starting with you, each player votes for death or torture. If death gets more votes, each opponent sacrifices a creature of their choice. If torture gets more votes or the vote is tied, each opponent loses 4 life.

Mardu Shadowspear

Whenever Mardu Shadowspear attacks, each opponent loses 1 life.
Dash {1}{B} (You may cast this spell for its dash cost. If you do, it gains haste, and it's returned from the battlefield to its owner's hand at the beginning of the next end step.)

Malakir Blood-Priest

When Malakir Blood-Priest enters, each opponent loses X life and you gain X life, where X is the number of creatures in your party. (Your party consists of up to one each of Cleric, Rogue, Warrior, and Wizard.)

Bastion of Remembrance

When Bastion of Remembrance enters, create a 1/1 white Human Soldier creature token.
Whenever a creature you control dies, each opponent loses 1 life and you gain 1 life.

Sanguine Syphoner

Whenever this creature attacks, each opponent loses 1 life and you gain 1 life.

Starscape Cleric

Offspring {2}{B} (You may pay an additional {2}{B} as you cast this spell. If you do, when this creature enters, create a 1/1 token copy of it.)
Flying
This creature can't block.
Whenever you gain life, each opponent loses 1 life.

Ichor Wellspring

When Ichor Wellspring enters or is put into a graveyard from the battlefield, draw a card.

Dreadhound

When Dreadhound enters, mill three cards. (Put the top three cards of your library into your graveyard.)
Whenever a creature dies or a creature card is put into a graveyard from a library, each opponent loses 1 life.

Maggot Carrier

When Maggot Carrier enters, each player loses 1 life.

Battlefield Butcher

{5}, {T}: Each opponent loses 2 life. This ability costs {1} less to activate for each creature card in your graveyard.

Vermin Gorger

{T}, Sacrifice another creature: Each opponent loses 2 life and you gain 2 life.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.