Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Imskir Iron-Eater

Affinity for artifacts (This spell costs {1} less to cast for each artifact you control.)
When Imskir Iron-Eater enters, you draw X cards and you lose X life, where X is half the number of artifacts you control, rounded down.
{3}{R}, Sacrifice an artifact: Imskir deals damage equal to the sacrificed artifact's mana value to any target.

Sensei's Divining Top

{1}: Look at the top three cards of your library, then put them back in any order.
{T}: Draw a card, then put Sensei's Divining Top on top of its owner's library.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.