Agent of Masks

At the beginning of your upkeep, each opponent loses 1 life. You gain life equal to the life lost this way.

Myrkul, Lord of Bones

As long as your life total is less than or equal to half your starting life total, Myrkul, Lord of Bones has indestructible.
Whenever another nontoken creature you control dies, you may exile it. If you do, create a token that's a copy of that card, except it's an enchantment and loses all other card types.

Drana's Emissary

Flying
At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Hazel of the Rootbloom

{T}, Pay 2 life, Tap X untapped tokens you control: Add X mana in any combination of colors.
At the beginning of your end step, create a token that's a copy of target token you control. If that token is a Squirrel, instead create two tokens that are copies of it.

Chancellor of the Dross

You may reveal this card from your opening hand. If you do, at the beginning of the first upkeep, each opponent loses 3 life, then you gain life equal to the life lost this way.
Flying, lifelink

Sheoldred, Whispering One

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.
At the beginning of each opponent's upkeep, that player sacrifices a creature of their choice.

Ichor Rats

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
When Ichor Rats enters, each player gets a poison counter.

Scrawling Crawler

At the beginning of your upkeep, each player draws a card.
Whenever an opponent draws a card, that player loses 1 life.

Phyrexian Swarmlord

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
At the beginning of your upkeep, create a 1/1 green Phyrexian Insect creature token with infect for each poison counter your opponents have.

Felidar Sovereign

Vigilance (Attacking doesn't cause this creature to tap.)
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your upkeep, if you have 40 or more life, you win the game.