Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Massacre Girl

Menace
When Massacre Girl enters, each other creature gets -1/-1 until end of turn. Whenever a creature dies this turn, each creature other than Massacre Girl gets -1/-1 until end of turn.

Smoke Bomb

Flash
All creatures have shroud. (They can't be the targets of spells or abilities.)
At the beginning of your upkeep, sacrifice Smoke Bomb. When you do, target creature you control can't be blocked this turn.

Vat Emergence

Put target creature card from a graveyard onto the battlefield under your control. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Flux Channeler

Whenever you cast a noncreature spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Distant Melody

Choose a creature type. Draw a card for each permanent you control of that type.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Escape Tunnel

{T}, Sacrifice Escape Tunnel: Search your library for a basic land card, put it onto the battlefield tapped, then shuffle.
{T}, Sacrifice Escape Tunnel: Target creature with power 2 or less can't be blocked this turn.

Drowned Catacomb

Drowned Catacomb enters tapped unless you control an Island or a Swamp.
{T}: Add {U} or {B}.

Voidwing Hybrid

Flying
Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When you proliferate, return Voidwing Hybrid from your graveyard to your hand.

Swamp

Inexorable Tide

Whenever you cast a spell, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Exotic Orchard

{T}: Add one mana of any color that a land an opponent controls could produce.

Serum Snare

Return target nonland permanent to its owner's hand. If that permanent had mana value 3 or less, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Drown in Ichor

Target creature gets -4/-4 until end of turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Choked Estuary

As Choked Estuary enters, you may reveal an Island or Swamp card from your hand. If you don't, Choked Estuary enters tapped.
{T}: Add {U} or {B}.

Notion Thief

Flash
If an opponent would draw a card except the first one they draw in each of their draw steps, instead that player skips that draw and you draw a card.

Evie Frye

Partner with Jacob Frye (When this creature enters, target player may put Jacob into their hand from their library, then shuffle.)
{1}, {T}: Draw a card, then discard a card. When you discard a creature card this way, target creature you control can't be blocked this turn.

Mirrex

{T}: Add {C}.
{T}: Add one mana of any color. Activate only if Mirrex entered this turn.
{3}, {T}: Create a 1/1 colorless Phyrexian Mite artifact creature token with toxic 1 and "This creature can't block." (Players dealt combat damage by it also get a poison counter.)

Imp's Mischief

Change the target of target spell with a single target. You lose life equal to that spell's mana value.

Path of Ancestry

Path of Ancestry enters tapped.
{T}: Add one mana of any color in your commander's color identity. When that mana is spent to cast a creature spell that shares a creature type with your commander, scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Brotherhood Headquarters

{T}: Add {C}.
{T}: Add one mana of any color. Spend this mana only to cast an Assassin spell or a spell that has freerunning, or to activate an ability of an Assassin source.

Vraska's Fall

Each opponent sacrifices a creature or planeswalker of their choice and gets a poison counter.

Temple of Deceit

This land enters tapped.
When this land enters, scry 1. (Look at the top card of your library. You may put that card on the bottom.)
{T}: Add {U} or {B}.

Island

Chart a Course

Draw two cards. Then discard a card unless you attacked this turn.

Radstorm

Storm (When you cast this spell, copy it for each spell cast before it this turn.)
Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Reject Imperfection

Counter target spell. If that spell's mana value was 3 or less, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Core Prowler

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
When Core Prowler dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Ramses, Assassin Lord

Deathtouch
Other Assassins you control get +1/+1.
Whenever a player loses the game, if they were attacked this turn by an Assassin you controlled, you win the game.

Prologue to Phyresis

Each opponent gets a poison counter.
Draw a card.

Ichor Rats

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
When Ichor Rats enters, each player gets a poison counter.

Vona's Hunger

Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
Each opponent sacrifices a creature of their choice. If you have the city's blessing, instead each opponent sacrifices half the creatures they control of their choice, rounded up.

Eagle Vision

Freerunning {1}{U} (You may cast this spell for its freerunning cost if you dealt combat damage to a player this turn with an Assassin or commander.)
Draw three cards.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Victimize

Choose two target creature cards in your graveyard. Sacrifice a creature. If you do, return the chosen cards to the battlefield tapped.

Assassin Gauntlet

When Assassin Gauntlet enters, attach it to up to one target creature you control. Tap all creatures target opponent controls.
Equipped creature gets +1/+1 and has "Whenever this creature deals combat damage to a player, draw a card, then discard a card."
Equip {2}

Flare of Malice

You may sacrifice a nontoken black creature rather than pay this spell's mana cost.
Each opponent sacrifices a creature or planeswalker with the greatest mana value among creatures and planeswalkers they control.

Hidden Blade

Flash
When Hidden Blade enters, attach it to target creature you control. If that creature is an Assassin, it gains deathtouch until end of turn.
Equipped creature gets +1/+0 and has first strike.
Equip {2}

Withering Torment

Destroy target creature or enchantment. You lose 2 life.

Tainted Strike

Target creature gets +1/+0 and gains infect until end of turn. (It deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Fellwar Stone

Crippling Fear

Choose a creature type. Creatures that aren't of the chosen type get -3/-3 until end of turn.

Plague Myr

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
{T}: Add {C}.

Dreamtide Whale

Vanishing 2 (This creature enters with two time counters on it. At the beginning of your upkeep, remove a time counter from it. When the last is removed, sacrifice it.)
Whenever a player casts their second spell each turn, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Glistening Sphere

Glistening Sphere enters tapped.
When Glistening Sphere enters, proliferate.
{T}: Add one mana of any color.
Corrupted — {T}: Add three mana of any one color. Activate only if an opponent has three or more poison counters.

Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Lively Dirge

Spree (Choose one or more additional costs.)
+ {1} — Search your library for a card, put it into your graveyard, then shuffle.
+ {2} — Return up to two creature cards with total mana value 4 or less from your graveyard to the battlefield.

Steady Progress

Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)
Draw a card.

Distorted Curiosity

Corrupted — This spell costs {2} less to cast if an opponent has three or more poison counters.
Draw two cards.

Aspirant's Ascent

Until end of turn, target creature gets +1/+3 and gains flying and toxic 1. (Players dealt combat damage by that creature also get a poison counter.)

Suq'Ata Assassin

Fear (This creature can't be blocked except by artifact creatures and/or black creatures.)
Whenever Suq'Ata Assassin attacks and isn't blocked, defending player gets a poison counter. (A player with ten or more poison counters loses the game.)

Doomed Necromancer

{B}, {T}, Sacrifice Doomed Necromancer: Return target creature card from your graveyard to the battlefield.

Dismal Backwater

This land enters tapped.
When this land enters, you gain 1 life.
{T}: Add {U} or {B}.

Mortuary Mire

Mortuary Mire enters tapped.
When Mortuary Mire enters, you may put target creature card from your graveyard on top of your library.
{T}: Add {B}.

Bident of Thassa

Whenever a creature you control deals combat damage to a player, you may draw a card.
{1}{U}, {T}: Creatures your opponents control attack this turn if able.

Slip Out the Back

Put a +1/+1 counter on target creature. It phases out. (Treat it and anything attached to it as though they don't exist until its controller's next turn.)

Black Market

Whenever a creature dies, put a charge counter on Black Market.
At the beginning of your first main phase, add {B} for each charge counter on Black Market.

Myriad Landscape

Myriad Landscape enters tapped.
{T}: Add {C}.
{2}, {T}, Sacrifice Myriad Landscape: Search your library for up to two basic land cards that share a land type, put them onto the battlefield tapped, then shuffle.

Shoot the Sheriff

Destroy target non-outlaw creature. (Assassins, Mercenaries, Pirates, Rogues, and Warlocks are outlaws. Everyone else is fair game.)

Restart Sequence

Freerunning {1}{B} (You may cast this spell for its freerunning cost if you dealt combat damage to a player this turn with an Assassin or commander.)
Return target creature card from your graveyard to the battlefield.

Infernal Grasp

Destroy target creature. You lose 2 life.

Unstoppable Slasher

Deathtouch
Whenever Unstoppable Slasher deals combat damage to a player, they lose half their life, rounded up.
When Unstoppable Slasher dies, if it had no counters on it, return it to the battlefield tapped under its owner's control with two stun counters on it.

Vorpal Sword

Equipped creature gets +2/+0 and has deathtouch.
{5}{B}{B}{B}: Until end of turn, Vorpal Sword gains "Whenever equipped creature deals combat damage to a player, that player loses the game."
Equip {B}{B}

Corrupted Resolve

Counter target spell if its controller is poisoned.

Changeling Outcast

Changeling (This card is every creature type.)
Changeling Outcast can't block and can't be blocked.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Sheoldred's Edict

Choose one —
• Each opponent sacrifices a nontoken creature of their choice.
• Each opponent sacrifices a creature token of their choice.
• Each opponent sacrifices a planeswalker of their choice.

Make an Example

Each opponent separates the creatures they control into two piles. For each opponent, you choose one of their piles. Each opponent sacrifices the creatures in their chosen pile. (Piles can be empty.)

Iridescent Vinelasher

Offspring {2} (You may pay an additional {2} as you cast this spell. If you do, when this creature enters, create a 1/1 token copy of it.)
Landfall — Whenever a land you control enters, this creature deals 1 damage to target opponent.

Royal Assassin

Malicious Affliction

Morbid — When you cast this spell, if a creature died this turn, you may copy Malicious Affliction and may choose a new target for the copy.
Destroy target nonblack creature.

Scarblade Elite

{T}, Exile an Assassin card from your graveyard: Destroy target creature.

Big Game Hunter

When Big Game Hunter enters, destroy target creature with power 4 or greater. It can't be regenerated.
Madness {B} (If you discard this card, discard it into exile. When you do, cast it for its madness cost or put it into your graveyard.)

Experimental Augury

Look at the top three cards of your library. Put one of them into your hand and the rest on the bottom of your library in any order. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Whisper of the Dross

Target creature gets -1/-1 until end of turn. Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Ravenloft Adventurer

When Ravenloft Adventurer enters, you take the initiative.
If a creature an opponent controls would die, instead exile it and put a hit counter on it.
Whenever Ravenloft Adventurer attacks, if you've completed a dungeon, defending player loses 1 life for each card they own in exile with a hit counter on it.

Contentious Plan

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Mari, the Killing Quill

Whenever a creature an opponent controls dies, exile it with a hit counter on it.
Assassins, Mercenaries, and Rogues you control have deathtouch and "Whenever this creature deals combat damage to a player, you may remove a hit counter from a card that player owns in exile. If you do, draw a card and create two Treasure tokens."

Etrata, the Silencer

Etrata, the Silencer can't be blocked.
Whenever Etrata deals combat damage to a player, exile target creature that player controls and put a hit counter on that card. That player loses the game if they own three or more exiled cards with hit counters on them. Etrata's owner shuffles Etrata into their library.

Tezzeret's Gambit

({U/P} can be paid with either {U} or 2 life.)
Draw two cards, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Sunken Hollow

({T}: Add {U} or {B}.)
Sunken Hollow enters tapped unless you control two or more basic lands.

Phyresis Outbreak

Each opponent gets a poison counter. Then each creature your opponents control gets -1/-1 until end of turn for each poison counter its controller has.

Tainted Isle

{T}: Add {C}.
{T}: Add {U} or {B}. Activate only if you control a Swamp.

Final Parting

Search your library for two cards. Put one into your hand and the other into your graveyard. Then shuffle.

Thrummingbird

Flying
Whenever Thrummingbird deals combat damage to a player, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Blighted Agent

Infect (This creature deals damage to creatures in the form of -1/-1 counters and to players in the form of poison counters.)
Blighted Agent can't be blocked.

Jacob Frye

Partner with Evie Frye (When this creature enters, target player may put Evie into their hand from their library, then shuffle.)
Whenever one or more Assassins you control deal combat damage to a player, exile up to one target Assassin card or card with freerunning from your graveyard. If you do, copy it. You may cast the copy.

Enter the Enigma

Target creature can't be blocked this turn.
Draw a card.

Blightbelly Rat

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
When Blightbelly Rat dies, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Pact of the Serpent

Choose a creature type. Target player draws X cards and loses X life, where X is the number of creatures they control of the chosen type.

The Revelations of Ezio

(As this Saga enters and after your draw step, add a lore counter. Sacrifice after III.)
I — Destroy target tapped creature an opponent controls.
II — Whenever an Assassin you control attacks this turn, put a +1/+1 counter on it.
III — Return target Assassin creature card from your graveyard to the battlefield with an additional +1/+1 counter on it.

Throne of Geth

{T}, Sacrifice an artifact: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Adéwalé, Breaker of Chains

When Adéwalé enters, reveal the top six cards of your library. Put an Assassin, Pirate, or Vehicle card from among them into your hand and the rest on the bottom of your library in a random order.
Whenever a Vehicle you control deals combat damage to a player, you may return Adéwalé from your graveyard to your hand.