Jon Irenicus, Shattered One

At the beginning of your end step, target opponent gains control of up to one target creature you control. Put two +1/+1 counters on it and tap it. It's goaded for the rest of the game and it gains "This creature can't be sacrificed." (It attacks each combat if able and attacks a player other than you if able.)
Whenever a creature you own but don't control attacks, you draw a card.

Cyclonic Rift

Return target nonland permanent you don't control to its owner's hand.
Overload {6}{U} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Sunken Ruins

{T}: Add {C}.
{U/B}, {T}: Add {U}{U}, {U}{B}, or {B}{B}.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Annul

Counter target artifact or enchantment spell.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Updraft Elemental

Breathe Your Last

Destroy target creature or planeswalker. You gain 1 life for each of its colors.

Visions of Brutality

Devoid (This card has no color.)
Enchant creature
Enchanted creature can't block.
Whenever enchanted creature deals damage, its controller loses that much life.

Jace's Erasure

Whenever you draw a card, you may have target player mill a card.

Fate Unraveler

Whenever an opponent draws a card, Fate Unraveler deals 1 damage to that player.

Negate

Sunken Hollow

({T}: Add {U} or {B}.)
Sunken Hollow enters tapped unless you control two or more basic lands.

Propaganda

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Dimir Doppelganger

{1}{U}{B}: Exile target creature card from a graveyard. Dimir Doppelganger becomes a copy of that card, except it has this ability.

Damnation

Destroy all creatures. They can't be regenerated.

Consuming Sepulcher

At the beginning of your upkeep, each opponent loses 1 life and you gain 1 life.

Tithing Blade

When Tithing Blade enters, each opponent sacrifices a creature of their choice.
Craft with creature {4}{B} ({4}{B}, Exile this artifact, Exile a creature you control or a creature card from your graveyard: Return this card transformed under its owner's control. Craft only as a sorcery.)

Tithing Blade // Consuming Sepulcher

Triton Shorestalker

Basilisk Collar

Equipped creature has deathtouch and lifelink. (Any amount of damage it deals to a creature is enough to destroy it. Damage dealt by this creature also causes you to gain that much life.)
Equip {2} ({2}: Attach to target creature you control. Equip only as a sorcery.)

Swamp

Sun Droplet

Whenever you're dealt damage, put that many charge counters on Sun Droplet.
At the beginning of each upkeep, you may remove a charge counter from Sun Droplet. If you do, you gain 1 life.

Paradise Plume

As Paradise Plume enters, choose a color.
Whenever a player casts a spell of the chosen color, you may gain 1 life.
{T}: Add one mana of the chosen color.

Vampire Envoy

Flying
Whenever Vampire Envoy becomes tapped, you gain 1 life.

Ebony Owl Netsuke

At the beginning of each opponent's upkeep, if that player has seven or more cards in hand, Ebony Owl Netsuke deals 4 damage to that player.

Island

Blood Artist

Whenever Blood Artist or another creature dies, target player loses 1 life and you gain 1 life.

Contaminated Bond

Enchant creature (Target a creature as you cast this. This card enters attached to that creature.)
Whenever enchanted creature attacks or blocks, its controller loses 3 life.

Demonic Taskmaster

Flying
At the beginning of your upkeep, sacrifice a creature other than Demonic Taskmaster.

Horn of Greed

Whenever a player plays a land, that player draws a card.

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Champion's Helm

Equipped creature gets +2/+2.
As long as equipped creature is legendary, it has hexproof. (It can't be the target of spells or abilities your opponents control.)
Equip {1}

Invisible Stalker

Hexproof (This creature can't be the target of spells or abilities your opponents control.)
Invisible Stalker can't be blocked.

Bloodgift Demon

Flying
At the beginning of your upkeep, target player draws a card and loses 1 life.

Fog Bank

Defender (This creature can't attack.)
Flying
Prevent all combat damage that would be dealt to and dealt by this creature.

Wretched Anurid

Whenever another creature enters, you lose 1 life.

Flesh Reaver

Whenever Flesh Reaver deals damage to a creature or opponent, Flesh Reaver deals that much damage to you.

Master of the Feast

Flying
At the beginning of your upkeep, each opponent draws a card.

Bloodthirsty Conqueror

Flying, deathtouch
Whenever an opponent loses life, you gain that much life. (Damage causes loss of life.)

Sol Ring

Deathgreeter

Whenever another creature dies, you may gain 1 life.

Changeling Outcast

Changeling (This card is every creature type.)
Changeling Outcast can't block and can't be blocked.

Sinister Possession

Enchant creature
Whenever enchanted creature attacks or blocks, its controller loses 2 life.

Warlock Class

(Gain the next level as a sorcery to add its ability.)
At the beginning of your end step, if a creature died this turn, each opponent loses 1 life.
{1}{B}: Level 2
When this Class becomes level 2, look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.
{6}{B}: Level 3
At the beginning of your end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Leadership Vacuum

Target player returns each commander they control from the battlefield to the command zone.
Draw a card.

Amphibian Downpour

Flash
Storm (When you cast this spell, copy it for each spell cast before it this turn. You may choose new targets for the copies. Copies become tokens.)
Enchant creature
Enchanted creature loses all abilities and is a blue Frog creature with base power and toughness 1/1.

Wall of Frost

Defender
Whenever Wall of Frost blocks a creature, that creature doesn't untap during its controller's next untap step.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Dissipation Field

Whenever a permanent deals damage to you, return it to its owner's hand.

Dark Confidant

At the beginning of your upkeep, reveal the top card of your library and put that card into your hand. You lose life equal to its mana value.

Xathrid Gorgon

Deathtouch (Any amount of damage this deals to a creature is enough to destroy it.)
{2}{B}, {T}: Put a petrification counter on target creature. It gains defender and becomes a colorless artifact in addition to its other types. Its activated abilities can't be activated. (A creature with defender can't attack.)

Dimir Aqueduct

Dimir Aqueduct enters tapped.
When Dimir Aqueduct enters, return a land you control to its owner's hand.
{T}: Add {U}{B}.

Coastal Breach

Undaunted (This spell costs {1} less to cast for each opponent.)
Return all nonland permanents to their owners' hands.

Shipwreck Marsh

Shipwreck Marsh enters tapped unless you control two or more other lands.
{T}: Add {U} or {B}.

Dimir Locket

{T}: Add {U} or {B}.
{U/B}{U/B}{U/B}{U/B}, {T}, Sacrifice Dimir Locket: Draw two cards.

Stronghold Discipline

Each player loses 1 life for each creature they control.

Reliquary Tower

You have no maximum hand size.
{T}: Add {C}.

Venomous Changeling

Changeling (This card is every creature type.)
Deathtouch

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Drowned Catacomb

Drowned Catacomb enters tapped unless you control an Island or a Swamp.
{T}: Add {U} or {B}.

Vampire Lacerator

At the beginning of your upkeep, you lose 1 life unless an opponent has 10 or less life.

Charity Extractor

Pitiless Horde

At the beginning of your upkeep, you lose 2 life.
Dash {2}{B}{B} (You may cast this spell for its dash cost. If you do, it gains haste, and it's returned from the battlefield to its owner's hand at the beginning of the next end step.)

Deep Freeze

Enchant creature
Enchanted creature has base power and toughness 0/4, has defender, loses all other abilities, and is a blue Wall in addition to its other colors and types.

Eaten by Piranhas

Flash (You may cast this spell any time you could cast an instant.)
Enchant creature
Enchanted creature loses all abilities and is a black Skeleton creature with base power and toughness 1/1. (It loses all other colors, card types, and creature types.)

Ormendahl, Profane Prince

Westvale Abbey

{T}: Add {C}.
{5}, {T}, Pay 1 life: Create a 1/1 white and black Human Cleric creature token.
{5}, {T}, Sacrifice five creatures: Transform Westvale Abbey, then untap it.

Westvale Abbey // Ormendahl, Profane Prince

Countersquall

Counter target noncreature spell. Its controller loses 2 life.

Callous Dismissal

Return target nonland permanent to its owner's hand.
Amass Zombies 1. (Put a +1/+1 counter on an Army you control. It's also a Zombie. If you don't control an Army, create a 0/0 black Zombie Army creature token first.)

Sygg, River Cutthroat

At the beginning of each end step, if an opponent lost 3 or more life this turn, you may draw a card. (Damage causes loss of life.)

Scrawling Crawler

At the beginning of your upkeep, each player draws a card.
Whenever an opponent draws a card, that player loses 1 life.

Creeping Bloodsucker

At the beginning of your upkeep, Creeping Bloodsucker deals 1 damage to each opponent. You gain life equal to the damage dealt this way.

Castaway's Despair

Enchant creature
When Castaway's Despair enters, tap enchanted creature.
Enchanted creature doesn't untap during its controller's untap step.

Vraan, Executioner Thane

Whenever one or more other creatures you control die, each opponent loses 2 life and you gain 2 life. This ability triggers only once each turn.

Endless Evil

Enchant creature you control
At the beginning of your upkeep, create a token that's a copy of enchanted creature, except the token is 1/1.
When enchanted creature dies, if that creature was a Horror, return Endless Evil to its owner's hand.

Evil Eye of Orms-by-Gore

Non-Eye creatures you control can't attack.
Evil Eye of Orms-by-Gore can't be blocked except by Walls.

Tormented Soul

Tormented Soul can't block and can't be blocked.

Call the Bloodline

{1}, Discard a card: Create a 1/1 black Vampire Knight creature token with lifelink. Activate only once each turn.