Fate Unraveler

Whenever an opponent draws a card, Fate Unraveler deals 1 damage to that player.

Seizan, Perverter of Truth

At the beginning of each player's upkeep, that player loses 2 life and draws two cards.

Crypt Ghast

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever you tap a Swamp for mana, add an additional {B}.

Wound Reflection

At the beginning of each end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Teferi's Puzzle Box

At the beginning of each player's draw step, that player puts the cards in their hand on the bottom of their library in any order, then draws that many cards.

Stinging Study

You draw X cards and you lose X life, where X is the mana value of a commander you own on the battlefield or in the command zone.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Defile

Target creature gets -1/-1 until end of turn for each Swamp you control.

Nykthos, Shrine to Nyx

{T}: Add {C}.
{2}, {T}: Choose a color. Add an amount of mana of that color equal to your devotion to that color. (Your devotion to a color is the number of mana symbols of that color in the mana costs of permanents you control.)

Ancient Craving

You draw three cards and you lose 3 life.

Grim Tutor

Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.

Master of the Feast

Flying
At the beginning of your upkeep, each opponent draws a card.

Necrodominance

Skip your draw step.
At the beginning of your end step, you may pay any amount of life. If you do, draw that many cards.
Your maximum hand size is five.
If a card or token would be put into your graveyard from anywhere, exile it instead.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Damnable Pact

Target player draws X cards and loses X life.

Infernal Grasp

Destroy target creature. You lose 2 life.

Scrawling Crawler

At the beginning of your upkeep, each player draws a card.
Whenever an opponent draws a card, that player loses 1 life.

Orcish Bowmasters

Flash
When Orcish Bowmasters enters and whenever an opponent draws a card except the first one they draw in each of their draw steps, Orcish Bowmasters deals 1 damage to any target. Then amass Orcs 1.

Imp's Mischief

Change the target of target spell with a single target. You lose life equal to that spell's mana value.

Blood Pact

Target player draws two cards and loses 2 life.

Bloodgift Demon

Flying
At the beginning of your upkeep, target player draws a card and loses 1 life.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Dauthi Voidwalker

Shadow (This creature can block or be blocked by only creatures with shadow.)
If a card would be put into an opponent's graveyard from anywhere, instead exile it with a void counter on it.
{T}, Sacrifice Dauthi Voidwalker: Choose an exiled card an opponent owns with a void counter on it. You may play it this turn without paying its mana cost.

Baleful Mastery

You may pay {1}{B} rather than pay this spell's mana cost.
If the {1}{B} cost was paid, an opponent draws a card.
Exile target creature or planeswalker.

Vampiric Tutor

Search your library for a card, then shuffle and put that card on top. You lose 2 life.

Mindcrank

Whenever an opponent loses life, that player mills that many cards. (Damage causes loss of life.)

Psychosis Crawler

Psychosis Crawler's power and toughness are each equal to the number of cards in your hand.
Whenever you draw a card, each opponent loses 1 life.

Lightning Greaves

Equipped creature has haste and shroud. (It can't be the target of spells or abilities.)
Equip {0}

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Dark Ritual

Sol Ring

Damnation

Destroy all creatures. They can't be regenerated.

Thought Vessel

You have no maximum hand size.
{T}: Add {C}.

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik, Son of Yawgmoth.

Cabal Stronghold

{T}: Add {C}.
{3}, {T}: Add {B} for each basic Swamp you control.

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Insatiable Avarice

Spree (Choose one or more additional costs.)
+ {2} — Search your library for a card, then shuffle and put that card on top.
+ {B}{B} — Target player draws three cards and loses 3 life.

Go for the Throat

Erebos, God of the Dead

Indestructible
As long as your devotion to black is less than five, Erebos isn't a creature. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)
Your opponents can't gain life.
{1}{B}, Pay 2 life: Draw a card.

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Sign in Blood

Reliquary Tower

Underworld Dreams

Whenever an opponent draws a card, Underworld Dreams deals 1 damage to that player.

Font of Mythos

At the beginning of each player's draw step, that player draws two additional cards.

Epicure of Blood

Whenever you gain life, each opponent loses 1 life.

Bloodletter of Aclazotz

Flying
If an opponent would lose life during your turn, they lose twice that much life instead. (Damage causes loss of life.)

Urborg, Tomb of Yawgmoth

Each land is a Swamp in addition to its other land types.

Feed the Swarm

Destroy target creature or enchantment an opponent controls. You lose life equal to that permanent's mana value.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Deadly Rollick

If you control a commander, you may cast this spell without paying its mana cost.
Exile target creature.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Peer into the Abyss

Target player draws cards equal to half the number of cards in their library and loses half their life. Round up each time.

Arcane Signet

The One Ring

Indestructible
When The One Ring enters, if you cast it, you gain protection from everything until your next turn.
At the beginning of your upkeep, you lose 1 life for each burden counter on The One Ring.
{T}: Put a burden counter on The One Ring, then draw a card for each burden counter on The One Ring.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Swamp

Cabal Coffers

{2}, {T}: Add {B} for each Swamp you control.

Night's Whisper

Reanimate

Put target creature card from a graveyard onto the battlefield under your control. You lose life equal to its mana value.

Howling Mine

At the beginning of each player's draw step, if Howling Mine is untapped, that player draws an additional card.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Decanter of Endless Water

You have no maximum hand size.
{T}: Add one mana of any color.

Ob Nixilis, the Hate-Twisted

Whenever an opponent draws a card, Ob Nixilis, the Hate-Twisted deals 1 damage to that player.
−2: Destroy target creature. Its controller draws two cards.

Dark Deal

Each player discards all the cards in their hand, then draws that many cards minus one.

Bojuka Bog

Bojuka Bog enters tapped.
When Bojuka Bog enters, exile target player's graveyard.
{T}: Add {B}.

Jet Medallion

Black spells you cast cost {1} less to cast.

Marauding Blight-Priest

Dread Presence

Whenever a Swamp you control enters, choose one —
• You draw a card and you lose 1 life.
• Dread Presence deals 2 damage to any target and you gain 2 life.

Black Market Connections

At the beginning of your first main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It has every creature type.)

Sensei's Divining Top

{1}: Look at the top three cards of your library, then put them back in any order.
{T}: Draw a card, then put Sensei's Divining Top on top of its owner's library.

Read the Bones

Scry 2, then draw two cards. You lose 2 life. (To scry 2, look at the top two cards of your library, then put any number of them on the bottom and the rest on top in any order.)