Yawgmoth, Thran Physician

Protection from Humans
Pay 1 life, Sacrifice another creature: Put a -1/-1 counter on up to one target creature and draw a card.
{B}{B}, Discard a card: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Crumbling Ashes

At the beginning of your upkeep, destroy target creature with a -1/-1 counter on it.

Midnight Banshee

Wither (This deals damage to creatures in the form of -1/-1 counters.)
At the beginning of your upkeep, put a -1/-1 counter on each nonblack creature.

Banewhip Punisher

When Banewhip Punisher enters, you may put a -1/-1 counter on target creature.
{B}, Sacrifice Banewhip Punisher: Destroy target creature that has a -1/-1 counter on it.

Dusk Urchins

Whenever Dusk Urchins attacks or blocks, put a -1/-1 counter on it.
When Dusk Urchins dies, draw a card for each -1/-1 counter on it.

Contagion Clasp

When Contagion Clasp enters, put a -1/-1 counter on target creature.
{4}, {T}: Proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Stigma Lasher

Wither (This deals damage to creatures in the form of -1/-1 counters.)
Whenever Stigma Lasher deals damage to a player, that player can't gain life for the rest of the game.

Nest of Scarabs

Whenever you put one or more -1/-1 counters on a creature, create that many 1/1 black Insect creature tokens.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Necroskitter

Wither (This deals damage to creatures in the form of -1/-1 counters.)
Whenever a creature an opponent controls with a -1/-1 counter on it dies, you may return that card to the battlefield under your control.

Harbinger of Night

At the beginning of your upkeep, put a -1/-1 counter on each creature.

Blasphemous Edict

You may pay {B} rather than pay this spell's mana cost if there are thirteen or more creatures on the battlefield.
Each player sacrifices thirteen creatures of their choice.

Skinrender

When Skinrender enters, put three -1/-1 counters on target creature.

Blood for the Blood God!

This spell costs {1} less to cast for each creature that died this turn.
Discard your hand, then draw eight cards. Blood for the Blood God! deals 8 damage to each opponent. Exile Blood for the Blood God!

Persistent Constrictor

At the beginning of each opponent's upkeep, they lose 1 life and you put a -1/-1 counter on up to one target creature they control.
Persist (When this creature dies, if it had no -1/-1 counters on it, return it to the battlefield under its owner's control with a -1/-1 counter on it.)

Chainer, Nightmare Adept

Discard a card: You may cast a creature spell from your graveyard this turn. Activate only once each turn.
Whenever a nontoken creature you control enters, if you didn't cast it from your hand, it gains haste until your next turn.

Kulrath Knight

Flying
Wither (This deals damage to creatures in the form of -1/-1 counters.)
Creatures your opponents control with counters on them can't attack or block.

Everlasting Torment

Players can't gain life.
Damage can't be prevented.
All damage is dealt as though its source had wither. (A source with wither deals damage to creatures in the form of -1/-1 counters.)

Kaervek the Merciless

Whenever an opponent casts a spell, Kaervek the Merciless deals damage equal to that spell's mana value to any target.

Grim Affliction

Put a -1/-1 counter on target creature, then proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Archfiend of Ifnir

Flying
Whenever you cycle or discard another card, put a -1/-1 counter on each creature your opponents control.
Cycling {2} ({2}, Discard this card: Draw a card.)

The Scorpion God

Whenever a creature with a -1/-1 counter on it dies, draw a card.
{1}{B}{R}: Put a -1/-1 counter on another target creature.
When The Scorpion God dies, return it to its owner's hand at the beginning of the next end step.

Carnifex Demon

Flying
Carnifex Demon enters with two -1/-1 counters on it.
{B}, Remove a -1/-1 counter from Carnifex Demon: Put a -1/-1 counter on each other creature.

Iron Myr

Party Thrasher

Noncreature spells you cast from exile have convoke. (Each creature you tap while casting a noncreature spell from exile pays for {1} or one mana of that creature's color.)
At the beginning of your first main phase, you may discard a card. If you do, exile the top two cards of your library, then choose one of them. You may play that card this turn.

Grim Poppet

Grim Poppet enters with three -1/-1 counters on it.
Remove a -1/-1 counter from Grim Poppet: Put a -1/-1 counter on another target creature.

Spitting Dilophosaurus

Whenever Spitting Dilophosaurus enters or attacks, put a -1/-1 counter on up to one target creature.
Creatures your opponents control with -1/-1 counters on them can't block.

Xantcha, Sleeper Agent

Xantcha, Sleeper Agent enters under the control of an opponent of your choice.
Xantcha attacks each combat if able and can't attack its owner or planeswalkers its owner controls.
{3}: Xantcha's controller loses 2 life and you draw a card. Any player may activate this ability.

Maha, Its Feathers Night

Flying, trample
Ward—Discard a card.
Creatures your opponents control have base toughness 1.

Soul Snuffers

When Soul Snuffers enters, put a -1/-1 counter on each creature.

Fume Spitter

Sacrifice Fume Spitter: Put a -1/-1 counter on target creature.

Black Sun's Zenith

Put X -1/-1 counters on each creature. Shuffle Black Sun's Zenith into its owner's library.

Mogis, God of Slaughter

Indestructible
As long as your devotion to black and red is less than seven, Mogis isn't a creature.
At the beginning of each opponent's upkeep, Mogis deals 2 damage to that player unless they sacrifice a creature of their choice.

Blowfly Infestation

Whenever a creature dies, if it had a -1/-1 counter on it, put a -1/-1 counter on target creature.

Lagomos, Hand of Hatred

At the beginning of combat on your turn, create a 2/1 red Elemental creature token with trample and haste. Sacrifice it at the beginning of the next end step.
{T}: Search your library for a card, put it into your hand, then shuffle. Activate only if five or more creatures died this turn.

Corrosive Mentor

Black creatures you control have wither. (They deal damage to creatures in the form of -1/-1 counters.)

Cauldron of Souls

{T}: Choose any number of target creatures. Each of those creatures gains persist until end of turn. (When it dies, if it had no -1/-1 counters on it, return it to the battlefield under its owner's control with a -1/-1 counter on it.)

Leaden Myr

The Lord of Pain

Menace
Your opponents can't gain life.
Whenever a player casts their first spell each turn, choose another target player. The Lord of Pain deals damage equal to that spell's mana value to the chosen player.

Blazemire Verge

{T}: Add {B}.
{T}: Add {R}. Activate only if you control a Swamp or a Mountain.

Hazoret the Fervent

Indestructible, haste
Hazoret the Fervent can't attack or block unless you have one or fewer cards in hand.
{2}{R}, Discard a card: Hazoret deals 2 damage to each opponent.

Mahadi, Emporium Master

At the beginning of your end step, create a Treasure token for each creature that died this turn. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")