Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Profane Transfusion

Two target players exchange life totals. You create an X/X colorless Horror artifact creature token, where X is the difference between those players' life totals.

Ayli, Eternal Pilgrim

Deathtouch
{1}, Sacrifice another creature: You gain life equal to the sacrificed creature's toughness.
{1}{W}{B}, Sacrifice another creature: Exile target nonland permanent. Activate only if you have at least 10 life more than your starting life total.

Twilight Prophet

Flying
Ascend (If you control ten or more permanents, you get the city's blessing for the rest of the game.)
At the beginning of your upkeep, if you have the city's blessing, reveal the top card of your library and put it into your hand. Each opponent loses X life and you gain X life, where X is that card's mana value.

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: Wall of Blood gets +1/+1 until end of turn.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with Tree of Perdition's toughness.

Mythos of Nethroi

Destroy target nonland permanent if it's a creature or if {G}{W} was spent to cast this spell.

Speaker of the Heavens

Vigilance, lifelink
{T}: Create a 4/4 white Angel creature token with flying. Activate only if you have at least 7 life more than your starting life total and only as a sorcery.

Heliod, Sun-Crowned

Indestructible
As long as your devotion to white is less than five, Heliod isn't a creature.
Whenever you gain life, put a +1/+1 counter on target creature or enchantment you control.
{1}{W}: Another target creature gains lifelink until end of turn.

Ajani's Pridemate

Whenever you gain life, put a +1/+1 counter on Ajani's Pridemate.

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters the battlefield, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)

Tree of Redemption

Defender
{T}: Exchange your life total with Tree of Redemption's toughness.

Evra, Halcyon Witness

Lifelink
{4}: Exchange your life total with Evra, Halcyon Witness's power.

Debt to the Deathless

Each opponent loses two times X life. You gain life equal to the life lost this way.

Vilis, Broker of Blood

Flying
{B}, Pay 2 life: Target creature gets -1/-1 until end of turn.
Whenever you lose life, draw that many cards. (Damage causes loss of life.)

Eternity Vessel

Eternity Vessel enters the battlefield with X charge counters on it, where X is your life total.
Landfall — Whenever a land enters the battlefield under your control, you may have your life total become the number of charge counters on Eternity Vessel.

Serra Avatar

Serra Avatar's power and toughness are each equal to your life total.
When Serra Avatar is put into a graveyard from anywhere, shuffle it into its owner's library.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Karlov of the Ghost Council

Whenever you gain life, put two +1/+1 counters on Karlov of the Ghost Council.
{W}{B}, Remove six +1/+1 counters from Karlov of the Ghost Council: Exile target creature.

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature and you return up to one target creature card from your graveyard to your hand.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Wall of Reverence

Defender, flying
At the beginning of your end step, you may gain life equal to the power of target creature you control.

Trostani, Selesnya's Voice

Whenever another creature enters the battlefield under your control, you gain life equal to that creature's toughness.
{1}{G}{W}, {T}: Populate. (Create a token that's a copy of a creature token you control.)

Heliod's Intervention

Choose one —
• Destroy X target artifacts and/or enchantments.
• Target player gains twice X life.

Resolute Archangel

Flying
When Resolute Archangel enters the battlefield, if your life total is less than your starting life total, it becomes equal to your starting life total.

Boon Reflection

If you would gain life, you gain twice that much life instead.

Magus of the Mirror

{T}, Sacrifice Magus of the Mirror: Exchange life totals with target opponent. Activate only during your upkeep.

K'rrik, Son of Yawgmoth

({B/P} can be paid with either {B} or 2 life.)
Lifelink
For each {B} in a cost, you may pay 2 life rather than pay that mana.
Whenever you cast a black spell, put a +1/+1 counter on K'rrik, Son of Yawgmoth.

Vona, Butcher of Magan

Vigilance, lifelink
{T}, Pay 7 life: Destroy target nonland permanent. Activate only during your turn.

Resplendent Angel

Flying
At the beginning of each end step, if you gained 5 or more life this turn, create a 4/4 white Angel creature token with flying and vigilance.
{3}{W}{W}{W}: Until end of turn, Resplendent Angel gets +2/+2 and gains lifelink.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Oketra's Last Mercy

Your life total becomes equal to your starting life total. Lands you control don't untap during your next untap step.

Exquisite Archangel

Flying
If you would lose the game, instead exile Exquisite Archangel and your life total becomes equal to your starting life total.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.