Astarion, the Decadent

Deathtouch, lifelink
At the beginning of your end step, choose one —
• Feed — Target opponent loses life equal to the amount of life they lost this turn.
• Friends — You gain life equal to the amount of life you gained this turn.

Calculating Lich

Menace
Whenever a creature attacks one of your opponents, that player loses 1 life.

Mortify

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Shroudstomper

Deathtouch
Whenever Shroudstomper enters or attacks, each opponent loses 2 life. You gain 2 life and draw a card.

Lifecreed Duo

Flying
Whenever another creature you control enters, you gain 1 life.

Elenda, Saint of Dusk

Lifelink, hexproof from instants
As long as your life total is greater than your starting life total, Elenda gets +1/+1 and has menace. Elenda gets an additional +5/+5 as long as your life total is at least 10 greater than your starting life total.

Sister Hospitaller

Medicus Ministorum — When Sister Hospitaller enters, return target creature card from your graveyard to the battlefield. You gain life equal to its mana value.

Deadly Tempest

Destroy all creatures. Each player loses life equal to the number of creatures they controlled that were destroyed this way.

Dawn of Hope

Whenever you gain life, you may pay {2}. If you do, draw a card.
{3}{W}: Create a 1/1 white Soldier creature token with lifelink.

Nighthawk Scavenger

Flying, deathtouch, lifelink
Nighthawk Scavenger's power is equal to 1 plus the number of card types among cards in your opponents' graveyards.

Well of Lost Dreams

Whenever you gain life, you may pay {X}, where X is less than or equal to the amount of life you gained. If you do, draw X cards.

Ancient Craving

You draw three cards and you lose 3 life.

Star Compass

Star Compass enters tapped.
{T}: Add one mana of any color that a basic land you control could produce.

Scouting Hawk

Flying
Keen Sight — When Scouting Hawk enters, if an opponent controls more lands than you, search your library for a basic Plains card, put it onto the battlefield tapped, then shuffle.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Dazzling Angel

Lunar Convocation

At the beginning of your end step, if you gained life this turn, each opponent loses 1 life.
At the beginning of your end step, if you gained and lost life this turn, create a 1/1 black Bat creature token with flying.
{1}{B}, Pay 2 life: Draw a card.

Disenchant

Isolated Chapel

Isolated Chapel enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Fraying Omnipotence

Each player loses half their life, then discards half the cards in their hand, then sacrifices half the creatures they control of their choice. Round up each time.

Life Insurance

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Whenever a nontoken creature dies, you lose 1 life and create a Treasure token.

Pontiff of Blight

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
Other creatures you control have extort. (If a creature has multiple instances of extort, each triggers separately.)

Scytheclaw

Living weapon (When this Equipment enters, create a 0/0 black Phyrexian Germ creature token, then attach this to it.)
Equipped creature gets +1/+1.
Whenever equipped creature deals combat damage to a player, that player loses half their life, rounded up.
Equip {3}

Fell

Essence Channeler

As long as you've lost life this turn, Essence Channeler has flying and vigilance.
Whenever you gain life, put a +1/+1 counter on Essence Channeler.
When Essence Channeler dies, put its counters on target creature you control.

Plains

Warlock Class

(Gain the next level as a sorcery to add its ability.)
At the beginning of your end step, if a creature died this turn, each opponent loses 1 life.
{1}{B}: Level 2
When this Class becomes level 2, look at the top three cards of your library. Put one of them into your hand and the rest into your graveyard.
{6}{B}: Level 3
At the beginning of your end step, each opponent loses life equal to the life they lost this turn. (Damage causes loss of life.)

Wayfarer's Bauble

{2}, {T}, Sacrifice Wayfarer's Bauble: Search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Starscape Cleric

Offspring {2}{B} (You may pay an additional {2}{B} as you cast this spell. If you do, when this creature enters, create a 1/1 token copy of it.)
Flying
This creature can't block.
Whenever you gain life, each opponent loses 1 life.

Intrepid Adversary

Lifelink
When Intrepid Adversary enters, you may pay {1}{W} any number of times. When you pay this cost one or more times, put that many valor counters on Intrepid Adversary.
Creatures you control get +1/+1 for each valor counter on Intrepid Adversary.

Sorin, Vengeful Bloodlord

During your turn, creatures and planeswalkers you control have lifelink.
+2: Sorin, Vengeful Bloodlord deals 1 damage to target player or planeswalker.
−X: Return target creature card with mana value X from your graveyard to the battlefield. That creature is a Vampire in addition to its other types.

Return to Dust

Exile target artifact or enchantment. If you cast this spell during your main phase, you may exile up to one other target artifact or enchantment.

Solemn Simulacrum

When this creature enters, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.
When this creature dies, you may draw a card.

Swamp

Voracious Hatchling

Lifelink
Voracious Hatchling enters with four -1/-1 counters on it.
Whenever you cast a white spell, remove a -1/-1 counter from Voracious Hatchling.
Whenever you cast a black spell, remove a -1/-1 counter from Voracious Hatchling.

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Marauding Blight-Priest

Whenever you gain life, each opponent loses 1 life.

Shineshadow Snarl

As Shineshadow Snarl enters, you may reveal a Plains or Swamp card from your hand. If you don't, Shineshadow Snarl enters tapped.
{T}: Add {W} or {B}.

Fiendish Panda

Whenever you gain life, put a +1/+1 counter on this creature.
When this creature dies, return another target non-Bear creature card with mana value less than or equal to this creature's power from your graveyard to the battlefield.

Elas il-Kor, Sadistic Pilgrim

Deathtouch
Whenever another creature you control enters, you gain 1 life.
Whenever another creature you control dies, each opponent loses 1 life.

Indulging Patrician

Flying
Lifelink (Damage dealt by this creature also causes you to gain that much life.)
At the beginning of your end step, if you gained 3 or more life this turn, each opponent loses 3 life.

Astarion's Thirst

Exile target creature. Put X +1/+1 counters on a commander creature you control, where X is the power of the creature exiled this way.

Sunbond

Enchant creature
Enchanted creature has "Whenever you gain life, put that many +1/+1 counters on this creature."

Tithe Drinker

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)

Vampire Scrivener

Flying
Whenever you gain life during your turn, put a +1/+1 counter on Vampire Scrivener.
Whenever you lose life during your turn, put a +1/+1 counter on Vampire Scrivener.

Exemplar of Light

Flying
Whenever you gain life, put a +1/+1 counter on this creature.
Whenever you put one or more +1/+1 counters on this creature, draw a card. This ability triggers only once each turn.

Arcane Signet

{T}: Add one mana of any color in your commander's color identity.

Rush of Dread

Spree (Choose one or more additional costs.)
+ {1} — Target opponent sacrifices half the creatures they control of their choice, rounded up.
+ {2} — Target opponent discards half the cards in their hand, rounded up.
+ {2} — Target opponent loses half their life, rounded up.

Grievous Wound

Enchant player
Enchanted player can't gain life.
Whenever enchanted player is dealt damage, they lose half their life, rounded up.

Treacherous Greed

As an additional cost to cast this spell, sacrifice a creature that dealt damage this turn.
Draw three cards. Each opponent loses 3 life and you gain 3 life.

Temple of Silence

This land enters tapped.
When this land enters, scry 1. (Look at the top card of your library. You may put that card on the bottom.)
{T}: Add {W} or {B}.

Knight of Dawn's Light

First strike
If you would gain life, you gain that much life plus 1 instead.
{1}{W}: Knight of Dawn's Light gets +1/+1 until end of turn.

Knight of Dusk's Shadow

Menace (This creature can't be blocked except by two or more creatures.)
Your opponents can't gain life.
{1}{B}: Knight of Dusk's Shadow gets +1/+1 until end of turn.

Syndicate Heavy

Extort (Whenever you cast a spell, you may pay {W/B}. If you do, each opponent loses 1 life and you gain that much life.)
At the beginning of each end step, if you gained 4 or more life this turn, investigate. (Create a Clue token. It's an artifact with "{2}, Sacrifice this artifact: Draw a card.")

Revenge

Double your life total. Target opponent loses half their life, rounded up.

Revival

Return target creature card with mana value 3 or less from your graveyard to the battlefield.

Revival // Revenge

Revenge of Ravens

Whenever a creature attacks you or a planeswalker you control, that creature's controller loses 1 life and you gain 1 life.

Leyline of Hope

If Leyline of Hope is in your opening hand, you may begin the game with it on the battlefield.
If you would gain life, you gain that much life plus 1 instead.
As long as you have at least 7 life more than your starting life total, creatures you control get +2/+2.

Cartographer's Hawk

Flying
When Cartographer's Hawk deals combat damage to a player who controls more lands than you, return it to its owner's hand. If you do, you may search your library for a Plains card, put it onto the battlefield tapped, then shuffle.

Scoured Barrens

This land enters tapped.
When this land enters, you gain 1 life.
{T}: Add {W} or {B}.

Marble Diamond

Marble Diamond enters tapped.
{T}: Add {W}.

Quietus Spike

Equipped creature has deathtouch.
Whenever equipped creature deals combat damage to a player, that player loses half their life, rounded up.
Equip {3}

Elspeth Tirel

+2: You gain 1 life for each creature you control.
−2: Create three 1/1 white Soldier creature tokens.
−5: Destroy all other permanents except for lands and tokens.

Tainted Field

{T}: Add {C}.
{T}: Add {W} or {B}. Activate only if you control a Swamp.

Restless Fortress

Restless Fortress enters tapped.
{T}: Add {W} or {B}.
{2}{W}{B}: Restless Fortress becomes a 1/4 white and black Nightmare creature until end of turn. It's still a land.
Whenever Restless Fortress attacks, defending player loses 2 life and you gain 2 life.

Gwaihir, Greatest of the Eagles

Flying
Whenever Gwaihir attacks, target attacking creature gains flying until end of turn.
At the beginning of each end step, if you gained 3 or more life this turn, create a 3/3 white Bird creature token with flying and "Whenever this creature attacks, target attacking creature gains flying until end of turn."

Command Tower

Twinblade Paladin

Whenever you gain life, put a +1/+1 counter on this creature.
As long as you have 25 or more life, this creature has double strike. (It deals both first-strike and regular combat damage.)

Bloodthirsty Aerialist

Flying
Whenever you gain life, put a +1/+1 counter on Bloodthirsty Aerialist.

Phyrexian Arena

At the beginning of your upkeep, you draw a card and you lose 1 life.

Exsanguinate

Each opponent loses X life. You gain life equal to the life lost this way.

Markov Purifier

Lifelink
At the beginning of your end step, if you gained life this turn, you may pay {2}. If you do, draw a card.

Pristine Talisman

Gray Merchant of Asphodel

When Gray Merchant of Asphodel enters, each opponent loses X life, where X is your devotion to black. You gain life equal to the life lost this way. (Each {B} in the mana costs of permanents you control counts toward your devotion to black.)