Vindicate

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Plains

Fumigate

Destroy all creatures. You gain 1 life for each creature destroyed this way.

Serra Ascendant

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
As long as you have 30 or more life, Serra Ascendant gets +5/+5 and has flying.

Cyclonic Rift

Return target nonland permanent you don't control to its owner's hand.
Overload {6}{U} (You may cast this spell for its overload cost. If you do, change "target" in its text to "each.")

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Absorb

Bloodthirsty Conqueror

Flying, deathtouch
Whenever an opponent loses life, you gain that much life. (Damage causes loss of life.)

Teferi's Protection

Until your next turn, your life total can't change and you gain protection from everything. All permanents you control phase out. (While they're phased out, they're treated as though they don't exist. They phase in before you untap during your untap step.)
Exile Teferi's Protection.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Island

Void Rend

This spell can't be countered.
Destroy target nonland permanent.

Witch of the Moors

Deathtouch
At the beginning of your end step, if you gained life this turn, each opponent sacrifices a creature of their choice and you return up to one target creature card from your graveyard to your hand.

Karlov of the Ghost Council

Whenever you gain life, put two +1/+1 counters on Karlov of the Ghost Council.
{W}{B}, Remove six +1/+1 counters from Karlov of the Ghost Council: Exile target creature.

Path to Exile

Exile target creature. Its controller may search their library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Soul Warden

Whenever another creature enters, you gain 1 life.

Counterspell

Strix Serenade

Counter target artifact, creature, or planeswalker spell. Its controller creates a 2/2 blue Bird creature token with flying.

Heliod's Intervention

Choose one —
• Destroy X target artifacts and/or enchantments.
• Target player gains twice X life.

Despark

Exile target permanent with mana value 4 or greater.

Oloro, Ageless Ascetic

At the beginning of your upkeep, you gain 2 life.
Whenever you gain life, you may pay {1}. If you do, draw a card and each opponent loses 1 life.
At the beginning of your upkeep, if Oloro, Ageless Ascetic is in the command zone, you gain 2 life.

Angel of Vitality

Flying
If you would gain life, you gain that much life plus 1 instead.
Angel of Vitality gets +2/+2 as long as you have 25 or more life.

Enduring Tenacity

Whenever you gain life, target opponent loses that much life.
When Enduring Tenacity dies, if it was a creature, return it to the battlefield under its owner's control. It's an enchantment. (It's not a creature.)

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Farewell

Choose one or more —
• Exile all artifacts.
• Exile all creatures.
• Exile all enchantments.
• Exile all graveyards.

Consecrated Sphinx

Flying
Whenever an opponent draws a card, you may draw two cards.

Voice of the Blessed

Whenever you gain life, put a +1/+1 counter on Voice of the Blessed.
As long as Voice of the Blessed has four or more +1/+1 counters on it, it has flying and vigilance.
As long as Voice of the Blessed has ten or more +1/+1 counters on it, it has indestructible.

Mana Drain

Counter target spell. At the beginning of your next main phase, add an amount of {C} equal to that spell's mana value.

Grand Abolisher

During your turn, your opponents can't cast spells or activate abilities of artifacts, creatures, or enchantments.

Sheoldred, the Apocalypse

Deathtouch
Whenever you draw a card, you gain 2 life.
Whenever an opponent draws a card, they lose 2 life.

Dark Ritual

Brainstorm

Draw three cards, then put two cards from your hand on top of your library in any order.

Permission Denied

Counter target noncreature spell. Your opponents can't cast noncreature spells this turn.

Ghostly Prison

Creatures can't attack you unless their controller pays {2} for each creature they control that's attacking you.

Rhystic Study

Whenever an opponent casts a spell, you may draw a card unless that player pays {1}.

An Offer You Can't Refuse

Counter target noncreature spell. Its controller creates two Treasure tokens. (They're artifacts with "{T}, Sacrifice this artifact: Add one mana of any color.")

Serra Avatar

Serra Avatar's power and toughness are each equal to your life total.
When Serra Avatar is put into a graveyard from anywhere, shuffle it into its owner's library.

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Fierce Guardianship

If you control a commander, you may cast this spell without paying its mana cost.
Counter target noncreature spell.

Damnation

Destroy all creatures. They can't be regenerated.

Disallow

Counter target spell, activated ability, or triggered ability. (Mana abilities can't be targeted.)

Divinity of Pride

Flying, lifelink
Divinity of Pride gets +4/+4 as long as you have 25 or more life.

Sol Ring

Demonic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Swamp

Archivist of Oghma

Flash
Whenever an opponent searches their library, you gain 1 life and draw a card.