Sierra, Nuka's Biggest Fan

The Nuka-Cola Challenge — Whenever one or more creatures you control deal combat damage to a player, put a quest counter on Sierra, Nuka's Biggest Fan and create a Food token.
Whenever you sacrifice a Food, target creature you control gets +X/+X until end of turn, where X is the number of quest counters on Sierra.

Leyline of Hope

If Leyline of Hope is in your opening hand, you may begin the game with it on the battlefield.
If you would gain life, you gain that much life plus 1 instead.
As long as you have at least 7 life more than your starting life total, creatures you control get +2/+2.

Felidar Sovereign

Vigilance, lifelink
At the beginning of your upkeep, if you have 40 or more life, you win the game.

Doubling Season

If an effect would create one or more tokens under your control, it creates twice that many of those tokens instead.
If an effect would put one or more counters on a permanent you control, it puts twice that many of those counters on that permanent instead.

The Gaffer

At the beginning of each end step, if you gained 3 or more life this turn, draw a card.

Alhammarret's Archive

If you would gain life, you gain twice that much life instead.
If you would draw a card except the first one you draw in each of your draw steps, draw two cards instead.

Trelasarra, Moon Dancer

Whenever you gain life, put a +1/+1 counter on Trelasarra, Moon Dancer and scry 1. (Look at the top card of your library. You may put that card on the bottom.)

Lathiel, the Bounteous Dawn

Lifelink
At the beginning of each end step, if you gained life this turn, distribute up to that many +1/+1 counters among any number of other target creatures.

Guide of Souls

Whenever another creature you control enters, you gain 1 life and get {E} (an energy counter).
Whenever you attack, you may pay {E}{E}{E}. When you do, put two +1/+1 counters and a flying counter on target attacking creature. It becomes an Angel in addition to its other types.

Tireless Provisioner

Landfall — Whenever a land you control enters, create a Food token or a Treasure token. (Food is an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life." Treasure is an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Idol of Oblivion

{T}: Draw a card. Activate only if you created a token this turn.
{8}, {T}, Sacrifice Idol of Oblivion: Create a 10/10 colorless Eldrazi creature token.

Samwise Gamgee

Whenever another nontoken creature you control enters, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")
Sacrifice three Foods: Return target historic card from your graveyard to your hand. (Artifacts, legendaries, and Sagas are historic.)

Angel of Vitality

Flying
If you would gain life, you gain that much life plus 1 instead.
Angel of Vitality gets +2/+2 as long as you have 25 or more life.

Prosperous Innkeeper

When Prosperous Innkeeper enters, create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")
Whenever another creature you control enters, you gain 1 life.

Cat Collector

When this creature enters, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this token: You gain 3 life.")
Whenever you gain life for the first time during each of your turns, create a 1/1 white Cat creature token.

Night of the Sweets' Revenge

When Night of the Sweets' Revenge enters, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")
Foods you control have "{T}: Add {G}."
{5}{G}{G}, Sacrifice Night of the Sweets' Revenge: Creatures you control get +X/+X until end of turn, where X is the number of Foods you control. Activate only as a sorcery.

Field-Tested Frying Pan

When Field-Tested Frying Pan enters, create a Food token, then create a 1/1 white Halfling creature token and attach Field-Tested Frying Pan to it.
Equipped creature has "Whenever you gain life, this creature gets +X/+X until end of turn, where X is the amount of life you gained."
Equip {2}

War Report

You gain life equal to the number of creatures on the battlefield plus the number of artifacts on the battlefield.

Academy Manufactor

If you would create a Clue, Food, or Treasure token, instead create one of each.

Hinterland Sanctifier

Whenever another creature you control enters, you gain 1 life.

Cleric Class

(Gain the next level as a sorcery to add its ability.)
If you would gain life, you gain that much life plus 1 instead.
{3}{W}: Level 2
Whenever you gain life, put a +1/+1 counter on target creature you control.
{4}{W}: Level 3
When this Class becomes level 3, return target creature card from your graveyard to the battlefield. You gain life equal to that creature's toughness.

Riot Control

You gain 1 life for each creature your opponents control. Prevent all damage that would be dealt to you this turn.

Trail of Crumbs

When Trail of Crumbs enters, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")
Whenever you sacrifice a Food, you may pay {1}. If you do, look at the top two cards of your library. You may reveal a permanent card from among them and put it into your hand. Put the rest on the bottom of your library in any order.

Exemplar of Light

Flying
Whenever you gain life, put a +1/+1 counter on this creature.
Whenever you put one or more +1/+1 counters on this creature, draw a card. This ability triggers only once each turn.

Peregrin Took

If one or more tokens would be created under your control, those tokens plus an additional Food token are created instead. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")
Sacrifice three Foods: Draw a card.

Trostani, Selesnya's Voice

Whenever another creature you control enters, you gain life equal to that creature's toughness.
{1}{G}{W}, {T}: Populate. (Create a token that's a copy of a creature token you control.)

Sovereign Okinec Ahau

Ward {2}
Whenever Sovereign Okinec Ahau attacks, for each creature you control with power greater than that creature's base power, put a number of +1/+1 counters on that creature equal to the difference.

Honor Troll

Vigilance
If you would gain life, you gain that much life plus 1 instead.
Honor Troll gets +2/+1 as long as you have 25 or more life.

Jaheira, Friend of the Forest

Tokens you control have "{T}: Add {G}."
Choose a Background (You can have a Background as a second commander.)

Hurska Sweet-Tooth

Whenever Hurska Sweet-Tooth attacks, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain life.")
Whenever you gain life, you may pay {G/W}. When you do, target creature gets +X/+X until end of turn, where X is the amount of life you gained.

Rosie Cotton of South Lane

When Rosie Cotton of South Lane enters, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")
Whenever you create a token, put a +1/+1 counter on target creature you control other than Rosie.

Sam, Loyal Attendant

Partner with Frodo, Adventurous Hobbit (When this creature enters, target player may put Frodo into their hand from their library, then shuffle.)
At the beginning of combat on your turn, create a Food token. (It's an artifact with "{2}, {T}, Sacrifice this artifact: You gain 3 life.")
Activated abilities of Foods you control cost {1} less to activate.

Prize Pig

Whenever you gain life, put that many ribbon counters on Prize Pig. Then if there are three or more ribbon counters on Prize Pig, remove those counters and untap it.
{T}: Add one mana of any color.

Nykthos Paragon

Whenever you gain life, you may put that many +1/+1 counters on each creature you control. Do this only once each turn.

Test of Endurance

At the beginning of your upkeep, if you have 50 or more life, you win the game.

Heliod, Sun-Crowned

Indestructible
As long as your devotion to white is less than five, Heliod isn't a creature.
Whenever you gain life, put a +1/+1 counter on target creature or enchantment you control.
{1}{W}: Another target creature gains lifelink until end of turn.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Soul Warden

Whenever another creature enters, you gain 1 life.

Fracturing Gust

Destroy all artifacts and enchantments. You gain 2 life for each permanent destroyed this way.

Heaped Harvest

When Heaped Harvest enters and when you sacrifice it, you may search your library for a basic land card, put it onto the battlefield tapped, then shuffle.
{2}, {T}, Sacrifice Heaped Harvest: You gain 3 life.

Gourmand's Talent

(Gain the next level as a sorcery to add its ability.)
During your turn, artifacts you control are Foods in addition to their other types and have "{2}, {T}, Sacrifice this artifact: You gain 3 life."
{2}{G}: Level 2
Whenever you gain life for the first time each turn, create a 3/3 green Raccoon creature token.
{3}{G}: Level 3
Whenever you gain life for the first time each turn, put a +1/+1 counter on each creature you control.

Kutzil, Malamet Exemplar

Your opponents can't cast spells during your turn.
Whenever one or more creatures you control each with power greater than its base power deals combat damage to a player, draw a card.

Rhox Faithmender

Lifelink (Damage dealt by this creature also causes you to gain that much life.)
If you would gain life, you gain twice that much life instead.

Elanor Gardner

When Elanor Gardner enters, create a Food token.
At the beginning of your end step, if you sacrificed a Food this turn, you may search your library for a basic land card, put that card onto the battlefield tapped, then shuffle.

Authority of the Consuls

Creatures your opponents control enter tapped.
Whenever a creature an opponent controls enters, you gain 1 life.

Essence Warden

Blossoming Bogbeast

Whenever Blossoming Bogbeast attacks, you gain 2 life. Then creatures you control gain trample and get +X/+X until end of turn, where X is the amount of life you gained this turn.

Selvala, Explorer Returned

Parley — {T}: Each player reveals the top card of their library. For each nonland card revealed this way, add {G} and you gain 1 life. Then each player draws a card.