Enlightened Tutor

Search your library for an artifact or enchantment card, reveal it, then shuffle and put that card on top.

Cloudsteel Kirin

Flying
Equipped creature has flying and "You can't lose the game and your opponents can't win the game."
Reconfigure {5} ({5}: Attach to target creature you control; or unattach from a creature. Reconfigure only as a sorcery. While attached, this isn't a creature.)

Ad Nauseam

Reveal the top card of your library and put that card into your hand. You lose life equal to its mana value. You may repeat this process any number of times.

Gideon of the Trials

+1: Until your next turn, prevent all damage target permanent would deal.
0: Until end of turn, Gideon of the Trials becomes a 4/4 Human Soldier creature with indestructible that's still a planeswalker. Prevent all damage that would be dealt to him this turn.
0: You get an emblem with "As long as you control a Gideon planeswalker, you can't lose the game and your opponents can't win the game."

Vault of Champions

Vault of Champions enters tapped unless you have two or more opponents.
{T}: Add {W} or {B}.

Plague Drone

Flying
Rot Fly — If an opponent would gain life, that player loses that much life instead.

Withering Boon

As an additional cost to cast this spell, pay 3 life.
Counter target creature spell.

Diabolic Intent

As an additional cost to cast this spell, sacrifice a creature.
Search your library for a card, put that card into your hand, then shuffle.

Idyllic Tutor

Search your library for an enchantment card, reveal it, put it into your hand, then shuffle.

Diabolic Tutor

Search your library for a card, put that card into your hand, then shuffle.

Blood Celebrant

{B}, Pay 1 life: Add one mana of any color.

Approach of the Second Sun

If this spell was cast from your hand and you've cast another spell named Approach of the Second Sun this game, you win the game. Otherwise, put Approach of the Second Sun into its owner's library seventh from the top and you gain 7 life.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Imp's Mischief

Change the target of target spell with a single target. You lose life equal to that spell's mana value.

Soul Echo

Soul Echo enters with X echo counters on it.
You don't lose the game for having 0 or less life.
At the beginning of your upkeep, sacrifice Soul Echo if there are no echo counters on it. Otherwise, target opponent may choose that for each 1 damage that would be dealt to you until your next upkeep, you remove an echo counter from Soul Echo instead.

Repay in Kind

Each player's life total becomes the lowest life total among all players.

Mana Confluence

{T}, Pay 1 life: Add one mana of any color.

Nine Lives

Hexproof
If a source would deal damage to you, prevent that damage and put an incarnation counter on Nine Lives.
When there are nine or more incarnation counters on Nine Lives, exile it.
When Nine Lives leaves the battlefield, you lose the game.

Tainted Sigil

{T}, Sacrifice Tainted Sigil: You gain life equal to the total life lost by all players this turn. (Damage causes loss of life.)

Caves of Koilos

{T}: Add {C}.
{T}: Add {W} or {B}. Caves of Koilos deals 1 damage to you.

Profane Tutor

Suspend 2—{1}{B} (Rather than cast this card from your hand, pay {1}{B} and exile it with two time counters on it. At the beginning of your upkeep, remove a time counter. When the last is removed, you may cast it without paying its mana cost.)
Search your library for a card, put that card into your hand, then shuffle.

Solemnity

Players can't get counters.
Counters can't be put on artifacts, creatures, enchantments, or lands.

Sickening Dreams

As an additional cost to cast this spell, discard X cards.
Sickening Dreams deals X damage to each creature and each player.

Mischievous Poltergeist

Flying
Pay 1 life: Regenerate Mischievous Poltergeist.

Marsh Flats

{T}, Pay 1 life, Sacrifice Marsh Flats: Search your library for a Plains or Swamp card, put it onto the battlefield, then shuffle.

Plunge into Darkness

Choose one —
• Sacrifice any number of creatures. You gain 3 life for each creature sacrificed this way.
• Pay any amount of life, then look at that many cards from the top of your library. Put one of those cards into your hand and exile the rest.
Entwine {B} (Choose both if you pay the entwine cost.)

Revenge

Double your life total. Target opponent loses half their life, rounded up.

Revival

Return target creature card with mana value 3 or less from your graveyard to the battlefield.

Revival // Revenge

Aetherflux Reservoir

Whenever you cast a spell, you gain 1 life for each spell you've cast this turn.
Pay 50 life: Aetherflux Reservoir deals 50 damage to any target.

Gideon of the Trials Emblem

As long as you control a Gideon planeswalker, you can't lose the game and your opponents can't win the game.

Magus of the Mirror

{T}, Sacrifice Magus of the Mirror: Exchange life totals with target opponent. Activate only during your upkeep.

Enduring Tenacity

Whenever you gain life, target opponent loses that much life.
When Enduring Tenacity dies, if it was a creature, return it to the battlefield under its owner's control. It's an enchantment. (It's not a creature.)

Sensei's Divining Top

{1}: Look at the top three cards of your library, then put them back in any order.
{T}: Draw a card, then put Sensei's Divining Top on top of its owner's library.

Doom Whisperer

Flying, trample
Pay 2 life: Surveil 2. (Look at the top two cards of your library, then put any number of them into your graveyard and the rest on top of your library in any order.)

Oketra's Last Mercy

Your life total becomes equal to your starting life total. Lands you control don't untap during your next untap step.

Dark Ritual

Grim Tutor

Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.

Plains

Angel's Grace

Split second (As long as this spell is on the stack, players can't cast spells or activate abilities that aren't mana abilities.)
You can't lose the game this turn and your opponents can't win the game this turn. Until end of turn, damage that would reduce your life total to less than 1 reduces it to 1 instead.

Axis of Mortality

At the beginning of your upkeep, you may have two target players exchange life totals.

Necropotence

Skip your draw step.
Whenever you discard a card, exile that card from your graveyard.
Pay 1 life: Exile the top card of your library face down. Put that card into your hand at the beginning of your next end step.

Children of Korlis

Sacrifice Children of Korlis: You gain life equal to the life you've lost this turn. (Damage causes loss of life.)

Shattered Sanctum

Shattered Sanctum enters tapped unless you control two or more other lands.
{T}: Add {W} or {B}.

Pestilence

At the beginning of the end step, if no creatures are on the battlefield, sacrifice Pestilence.
{B}: Pestilence deals 1 damage to each creature and each player.

Triskaidekaphobia

At the beginning of your upkeep, choose one —
• Each player with exactly 13 life loses the game, then each player gains 1 life.
• Each player with exactly 13 life loses the game, then each player loses 1 life.

Exquisite Blood

Whenever an opponent loses life, you gain that much life.

Rebuff the Wicked

Counter target spell that targets a permanent you control.

Delaying Shield

If damage would be dealt to you, put that many delay counters on Delaying Shield instead.
At the beginning of your upkeep, remove all delay counters from Delaying Shield. For each delay counter removed this way, you lose 1 life unless you pay {1}{W}.

Beacon of Immortality

Double target player's life total. Shuffle Beacon of Immortality into its owner's library.

Skirge Familiar

False Cure

Until end of turn, whenever a player gains life, that player loses 2 life for each 1 life they gained.

Selenia, Dark Angel

Flying
Pay 2 life: Return Selenia, Dark Angel to its owner's hand.

Platinum Angel

Flying
You can't lose the game and your opponents can't win the game.

Glacial Chasm

Cumulative upkeep—Pay 2 life. (At the beginning of your upkeep, put an age counter on this permanent, then sacrifice it unless you pay its upkeep cost for each age counter on it.)
When Glacial Chasm enters, sacrifice a land.
Creatures you control can't attack.
Prevent all damage that would be dealt to you.

Toxic Deluge

As an additional cost to cast this spell, pay X life.
All creatures get -X/-X until end of turn.

Black Market Connections

At the beginning of your first main phase, choose one or more —
• Sell Contraband — Create a Treasure token. You lose 1 life.
• Buy Information — Draw a card. You lose 2 life.
• Hire a Mercenary — Create a 3/2 colorless Shapeshifter creature token with changeling. You lose 3 life. (It has every creature type.)

Deadly Rollick

If you control a commander, you may cast this spell without paying its mana cost.
Exile target creature.

The Cruelty of Gix

Read ahead (Choose a chapter and start with that many lore counters. Add one after your draw step. Skipped chapters don't trigger. Sacrifice after III.)
I — Target opponent reveals their hand. You choose a creature or planeswalker card from it. That player discards that card.
II — Search your library for a card, put that card into your hand, then shuffle. You lose 3 life.
III — Put target creature card from a graveyard onto the battlefield under your control.

Near-Death Experience

At the beginning of your upkeep, if you have exactly 1 life, you win the game.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Soul Conduit

{6}, {T}: Two target players exchange life totals.

Wishclaw Talisman

Wishclaw Talisman enters with three wish counters on it.
{1}, {T}, Remove a wish counter from Wishclaw Talisman: Search your library for a card, put it into your hand, then shuffle. An opponent gains control of Wishclaw Talisman. Activate only during your turn.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Swords to Plowshares

Exile target creature. Its controller gains life equal to its power.

Hex Parasite

{X}{B/P}: Remove up to X counters from target permanent. For each counter removed this way, Hex Parasite gets +1/+0 until end of turn. ({B/P} can be paid with either {B} or 2 life.)

Godless Shrine

({T}: Add {W} or {B}.)
As Godless Shrine enters, you may pay 2 life. If you don't, it enters tapped.

Brainspoil

Destroy target creature that isn't enchanted. It can't be regenerated.
Transmute {1}{B}{B} ({1}{B}{B}, Discard this card: Search your library for a card with the same mana value as this card, reveal it, put it into your hand, then shuffle. Transmute only as a sorcery.)

Smothering Tithe

Whenever an opponent draws a card, that player may pay {2}. If the player doesn't, you create a Treasure token. (It's an artifact with "{T}, Sacrifice this artifact: Add one mana of any color.")

Phyrexian Unlife

You don't lose the game for having 0 or less life.
As long as you have 0 or less life, all damage is dealt to you as though its source had infect. (Damage is dealt to you in the form of poison counters.)

Dark Petition

Search your library for a card, put that card into your hand, then shuffle.
Spell mastery — If there are two or more instant and/or sorcery cards in your graveyard, add {B}{B}{B}.

Vizkopa Guildmage

{1}{W}{B}: Target creature gains lifelink until end of turn.
{1}{W}{B}: Whenever you gain life this turn, each opponent loses that much life.

Angelic Enforcer

Flying
You have hexproof.
Angelic Enforcer's power and toughness are each equal to your life total.
Whenever Angelic Enforcer attacks, double your life total.

Enduring Angel

Flying, double strike
You have hexproof.
If your life total would be reduced to 0 or less, instead transform Enduring Angel and your life total becomes 3. Then if Enduring Angel didn't transform this way, you lose the game.

Enduring Angel // Angelic Enforcer

Wall of Blood

Defender (This creature can't attack.)
Pay 1 life: Wall of Blood gets +1/+1 until end of turn.

Tree of Perdition

Defender
{T}: Exchange target opponent's life total with Tree of Perdition's toughness.

Isolated Chapel

Isolated Chapel enters tapped unless you control a Plains or a Swamp.
{T}: Add {W} or {B}.

Dawn Charm

Choose one —
• Prevent all combat damage that would be dealt this turn.
• Regenerate target creature.
• Counter target spell that targets you.

Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Reprieve

Return target spell to its owner's hand.
Draw a card.

Bolas's Citadel

You may look at the top card of your library any time.
You may play lands and cast spells from the top of your library. If you cast a spell this way, pay life equal to its mana value rather than pay its mana cost.
{T}, Sacrifice ten nonland permanents: Each opponent loses 10 life.

Swamp

City of Brass

Whenever City of Brass becomes tapped, it deals 1 damage to you.
{T}: Add one mana of any color.