Defiant Bloodlord

Flying
Whenever you gain life, target opponent loses that much life.

Staff of Domination

{1}: Untap Staff of Domination.
{2}, {T}: You gain 1 life.
{3}, {T}: Untap target creature.
{4}, {T}: Tap target creature.
{5}, {T}: Draw a card.

Serpent Generator

{4}, {T}: Create a 1/1 colorless Snake artifact creature token. It has "Whenever this creature deals damage to a player, that player gets a poison counter." (A player with ten or more poison counters loses the game.)

Shard of the Nightbringer

Flying
Drain Life — When Shard of the Nightbringer enters, if you cast it, target opponent loses half their life, rounded up. You gain life equal to the life lost this way.

Command Tower

{T}: Add one mana of any color in your commander's color identity.

Vraska's Fall

Each opponent sacrifices a creature or planeswalker of their choice and gets a poison counter.

Trazyn the Infinite

Deathtouch
Prismatic Gallery — As long as Trazyn the Infinite is on the battlefield, it has all activated abilities of all artifact cards in your graveyard.

Shard of the Void Dragon

Flying
Spear of the Void Dragon — Whenever Shard of the Void Dragon attacks, each opponent sacrifices a nonland permanent of their choice.
Matter Absorption — Whenever an artifact is put into a graveyard from the battlefield or is put into exile from the battlefield, put two +1/+1 counters on Shard of the Void Dragon.

Infectious Inquiry

You draw two cards and you lose 2 life. Each opponent gets a poison counter.

Sheoldred, Whispering One

Swampwalk (This creature can't be blocked as long as defending player controls a Swamp.)
At the beginning of your upkeep, return target creature card from your graveyard to the battlefield.
At the beginning of each opponent's upkeep, that player sacrifices a creature of their choice.

Necrogen Rotpriest

Toxic 2 (Players dealt combat damage by this creature also get two poison counters.)
Whenever a creature you control with toxic deals combat damage to a player, that player gets an additional poison counter.
{1}{B}{G}: Target creature you control with toxic gains deathtouch until end of turn.

Decimator Web

{4}, {T}: Target opponent loses 2 life, gets a poison counter, then mills six cards.

Atraxa, Praetors' Voice

Flying, vigilance, deathtouch, lifelink
At the beginning of your end step, proliferate. (Choose any number of permanents and/or players, then give each another counter of each kind already there.)

Contaminant Grafter

Trample, toxic 1
Whenever one or more creatures you control deal combat damage to one or more players, proliferate.
Corrupted — At the beginning of your end step, if an opponent has three or more poison counters, draw a card, then you may put a land card from your hand onto the battlefield.

Sanguine Bond

Whenever you gain life, target opponent loses that much life.

Pili-Pala

Flying
{2}, {Q}: Add one mana of any color. ({Q} is the untap symbol.)

Infectious Bite

Target creature you control deals damage equal to its power to target creature you don't control. Each opponent gets a poison counter.

Glistening Sphere

Glistening Sphere enters tapped.
When Glistening Sphere enters, proliferate.
{T}: Add one mana of any color.
Corrupted — {T}: Add three mana of any one color. Activate only if an opponent has three or more poison counters.

Caress of Phyrexia

Target player draws three cards, loses 3 life, and gets three poison counters.

Phyrexian Obliterator

Trample
Whenever a source deals damage to Phyrexian Obliterator, that source's controller sacrifices that many permanents of their choice.

Phyresis Outbreak

Each opponent gets a poison counter. Then each creature your opponents control gets -1/-1 until end of turn for each poison counter its controller has.

Sol Ring

Commander's Sphere

{T}: Add one mana of any color in your commander's color identity.
Sacrifice Commander's Sphere: Draw a card.

Pistus Strike

Destroy target creature with flying. Its controller gets a poison counter.

Prologue to Phyresis

Each opponent gets a poison counter.
Draw a card.

Venerated Rotpriest

Toxic 1 (Players dealt combat damage by this creature also get a poison counter.)
Whenever a creature you control becomes the target of a spell, target opponent gets a poison counter.

Vito, Thorn of the Dusk Rose

Whenever you gain life, target opponent loses that much life.
{3}{B}{B}: Creatures you control gain lifelink until end of turn.

Noxious Assault

Creatures you control get +2/+2 until end of turn. Whenever a creature blocks this turn, its controller gets a poison counter.